{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:52:58Z","timestamp":1791355978876,"version":"4.3.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2026,10,6]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">The periaortic microenvironment visible on routine computed tomography angiography remains incompletely characterized in type B aortic dissection (TBAD). We evaluated computed tomography angiography\u2013based periaortic adipose tissue (PAAT) phenotypes associated with prevalent TBAD and explored a prespecified Tear Risk Index for post\u2013thoracic endovascular aortic repair aortic dilation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">This retrospective case\u2013control study included 100 patients with TBAD undergoing primary thoracic endovascular aortic repair and 50 normal controls frequency matched by age and sex. Deep learning\u2013assisted, radiologist\u2010reviewed segmentation quantified multilayer PAAT and aortic morphology. Interreader reproducibility was assessed using intraclass correlation coefficients and Bland\u2013Altman analyses. Group comparisons, receiver operating characteristic analyses, and adjusted logistic regression were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">Compared with controls, patients with TBAD had larger aortic volume and higher 3\u2010mm PAAT volume, fat attenuation index, and fragmentation index. Aortic volume showed an area under the curve of 0.966 (95% CI, 0.941\u20130.991); corresponding values for 3\u2010mm PAAT volume, fat attenuation index, and fragmentation index were 0.614, 0.819, and 0.716, respectively. Interreader intraclass correlation coefficients for selected 3\u2010mm PAAT measures ranged from 0.822 to 0.907. Principal TBAD\u2010control PAAT findings remained supported after false discovery rate correction, whereas post\u2013thoracic endovascular aortic repair PAAT differences were not robust. Tear Risk Index showed limited exploratory discrimination for dilation status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Selected 3\u2010mm PAAT measures characterize a reproducible computed tomography angiography\u2013based imaging phenotype associated with prevalent TBAD and may complement conventional aortic morphology. These findings are hypothesis generating, and Tear Risk Index should not be used as a standalone clinical predictor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.126.051823","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:15:36Z","timestamp":1790680536000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Computed Tomography\u2013Based Periaortic Adipose Tissue Imaging Phenotypes in Type B Aortic Dissection: A Retrospective Case\u2013Control Study"],"prefix":"10.1161","volume":"15","author":[{"given":"Hao\u2010jie","family":"Lei","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Guangxi Medical University","place":["Nanning, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang\u2010ren","family":"Huang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Guangxi Medical 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