{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:31:09Z","timestamp":1792305069243,"version":"4.4.0"},"reference-count":736,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Purpose\u2014<\/jats:title>\n                    <jats:p>This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\u2014<\/jats:title>\n                    <jats:p>\n                      Writing group members were nominated by the committee chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association (AHA) Stroke Council Scientific Statement Oversight Committee and the AHA Manuscript Oversight Committee. The writing group used systematic literature reviews (covering the time since the last review was published in 2006 up to April 2009), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations using standard AHA criteria (\n                      <jats:xref ref-type=\"table\">Tables 1<\/jats:xref>\n                      and\n                      <jats:xref ref-type=\"table\">2<\/jats:xref>\n                      ). All members of the writing group had the opportunity to comment on the recommendations and approved the final version of this document. The guideline underwent extensive peer review by the Stroke Council leadership and the AHA scientific statements oversight committees before consideration and approval by the AHA Science Advisory and Coordinating Committee.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results\u2014<\/jats:title>\n                    <jats:p>Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race\/ethnicity, and genetic predisposition. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat distribution. Less well-documented or potentially modifiable risk factors include the metabolic syndrome, excessive alcohol consumption, drug abuse, use of oral contraceptives, sleep-disordered breathing, migraine, hyperhomocysteinemia, elevated lipoprotein(a), hypercoagulability, inflammation, and infection. Data on the use of aspirin for primary stroke prevention are reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion\u2014<\/jats:title>\n                    <jats:p>Extensive evidence identifies a variety of specific factors that increase the risk of a first stroke and that provide strategies for reducing that risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/str.0b013e3181fcb238","type":"journal-article","created":{"date-parts":[[2010,12,2]],"date-time":"2010-12-02T23:00:02Z","timestamp":1291330802000},"page":"517-584","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1252,"title":["Guidelines for the Primary Prevention of Stroke"],"prefix":"10.1161","volume":"42","author":[{"given":"Larry B.","family":"Goldstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl D.","family":"Bushnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Appel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne T.","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seemant","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Creager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Culebras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H.","family":"Eckel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Hart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith A.","family":"Hinchey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia J.","family":"Howard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.","family":"Jauch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Meschia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesley S.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.V. (Ian)","family":"Nixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192667"},{"key":"e_1_3_2_3_2","first-page":"373","article-title":"Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989","volume":"27","author":"Brown RD","year":"1996","unstructured":"Brown RD, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO . Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989. Stroke. 1996;27:373\u2013380.","journal-title":"Stroke"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/hs1001.096193"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(98)70019-5"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.181486"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540280029015"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.7.1507"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.781062"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000223048.70103.f1"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000054482.38437.13"},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/j.0022-0337.2001.65.10.tb03442.x","article-title":"Definitions of risk","volume":"65","author":"Burt BA","year":"2001","unstructured":"Burt BA . Definitions of risk. J Dent Educ. 2001;65:1007\u20131008.","journal-title":"J Dent Educ"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.9.1840"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/08830738060210050301"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2005.10.016"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-005-3201-9"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000080678.09344.8D"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.24.2939"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.9.1479"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.487090"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.23.11.1551"},{"key":"e_1_3_2_22_2","first-page":"1","article-title":"Summary health statistics for U.S. adults: National Health Interview Survey, 2006","author":"Pleis JR","year":"2007","unstructured":"Pleis JR, Lethbridge-Cejku M Summary health statistics for U.S. adults: National Health Interview Survey, 2006. Vital Health Stat. 10. 2007:1\u2013153.","journal-title":"Vital Health Stat. 10"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.4.736"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009445"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000110982.74967.39"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1958"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000172428.78411.b0"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199609123351102"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.191259"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.4.463"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000077257.27430.7e"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2003.01353.x"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.34.1.57"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000242766.65550.92"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.11.2120"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh225"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000191402.41914.d2"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1995.00430120109013"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009957"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450100057025"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.561688"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.772285"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000107187.84390.AA"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000121646.23955.0f"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.484618"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-200111002-00017"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.2.487"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1517\/phgs.4.1.53.22587"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh023"},{"key":"e_1_3_2_50_2","first-page":"129","volume-title":"Genetics of Cerebrovascular Disease","author":"Ortel T","year":"1999","unstructured":"Ortel T . Genetics of coagulation disorders. In: , Alberts M , ed. Genetics of Cerebrovascular Disease. Armonk, NY: Futura Publishing;1999:129\u2013156."},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/369064a0"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.10.1724"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/91.10.677"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.40.645"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.32.8.1793"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-01-0111"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1191\/096120300680198971"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)80222-8"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200001000-00007"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(00)00215-0"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142842"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142447"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072366"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21590"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06007"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21480"},{"key":"e_1_3_2_67_2","first-page":"A273","article-title":"Clinical phenotypes and genetic data in 15 unrelated families","volume":"45","author":"Tournier-Lasserve E","year":"1995","unstructured":"Tournier-Lasserve E, Joutel A, Chabriat H . Clinical phenotypes and genetic data in 15 unrelated families. Neurology. 1995;45(suppl 4):A273.","journal-title":"Neurology"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2990.1999.00198.x"},{"issue":"1","key":"e_1_3_2_69_2","first-page":"65","article-title":"A possible advance in arterial gene therapy for aortic complications in the Marfan syndrome by local transfer of an antisense Mg-dependent hammerhead ribozyme","volume":"14","author":"Durlach J","year":"2001","unstructured":"Durlach J . A possible advance in arterial gene therapy for aortic complications in the Marfan syndrome by local transfer of an antisense Mg-dependent hammerhead ribozyme. Magnes Res. 14(1\u20132):65\u201367, 2001.","journal-title":"Magnes Res"},{"key":"e_1_3_2_70_2","first-page":"3733","volume-title":"The Metabolic and Molecular Bases of Inherited Disease","author":"Desnick R","year":"2001","unstructured":"Desnick R, Ioannou Y, Eng C . Alpha-galactosidase A deficiency: Fabry disease. In: , Scriver C, Beauder A, Sly W , et al. , eds. The Metabolic and Molecular Bases of Inherited Disease. 8th ed. New York, NY: McGraw-Hill; 2001:3733\u20133774.","edition":"8"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/18.1.33"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107053450102"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.21.2743"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-2-4"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000598"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1996.tb01181.x"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000014773.57733.3e"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.83.3.0426"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540260108026"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.542571"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000342999.99907.fd"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0804458"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.88.3.0436"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-32"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0670"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801936"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61845-0"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0809171"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808227"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.18.2300"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11911-8"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.15.1882"},{"key":"e_1_3_2_94_2","first-page":"239","volume-title":"Hypertension Primer: The Essentials of High Blood Pressure","author":"Wolf PA","year":"1999","unstructured":"Wolf PA . Cerebrovascular risk. In: , Izzo JLJ, Black HR , eds. Hypertension Primer: The Essentials of High Blood Pressure. Baltimore, Md: Lippincott, Williams & Wilkins;1999:239."},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.0000142248.54761.56"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.113357"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2005.00165.x"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.S2.555"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.25.3.305"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.8.1003"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2534"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14739-3"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b1665"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008161"},{"key":"e_1_3_2_105_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.23.2981"},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)04311-6"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801369"},{"key":"e_1_3_2_108_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03460240051027"},{"key":"e_1_3_2_109_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010273"},{"key":"e_1_3_2_110_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.37.1.12"},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2002.02045.x"},{"key":"e_1_3_2_112_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.5.525"},{"key":"e_1_3_2_113_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.3.312"},{"key":"e_1_3_2_114_2","doi-asserted-by":"publisher","DOI":"10.1161\/hs0102.101081"},{"key":"e_1_3_2_115_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.510073"},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000170710.95689.41"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000190838.02954.e8"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000100165.36466.95"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000065200.93070.32"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000177480.62341.6b"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6676.789"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1159\/000015893"},{"key":"e_1_3_2_123_2","volume-title":"Reducing the Health Consequences of Smoking: 25 Years of Progress. A Report of the Surgeon General","year":"1989","unstructured":"Reducing the Health Consequences of Smoking: 25 Years of Progress. A Report of the Surgeon General. Rockville, Md: US Dept of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 1989. DHHS publication (CDC) 89\u20138411."},{"key":"e_1_3_2_124_2","first-page":"1","article-title":"The surgeon general's 1989 report on reducing the health consequences of smoking: 25 years of progress","volume":"38","year":"1989","unstructured":"The surgeon general's 1989 report on reducing the health consequences of smoking: 25 years of progress. MMWR Morb Mortal Wkly Rep. 1989;38(suppl 2):1\u201332.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.6.706"},{"key":"e_1_3_2_126_2","first-page":"1226","article-title":"Smoking-attributable mortality, years of potential life lost, and productivity losses\u2013United States, 2000\u20132004","volume":"57","year":"2008","unstructured":"Smoking-attributable mortality, years of potential life lost, and productivity losses\u2013United States, 2000\u20132004. MMWR Morb Mortal Wkly Rep. 2008;57:1226\u20131228.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_127_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.496752"},{"key":"e_1_3_2_128_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2003.10.010"},{"key":"e_1_3_2_129_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)12393-8"},{"key":"e_1_3_2_130_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)12394-6"},{"key":"e_1_3_2_131_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000112973.00867.98"},{"key":"e_1_3_2_132_2","volume-title":"The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General","year":"2006","unstructured":"The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General. Atlanta, GA: US Dept of Health and Human Services, Centers for Disease Control and Prevention, Coordinating Center for Health Promotion, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2006."},{"key":"e_1_3_2_133_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.492215"},{"key":"e_1_3_2_134_2","doi-asserted-by":"publisher","DOI":"10.1136\/tc.8.2.156"},{"key":"e_1_3_2_135_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.784801"},{"key":"e_1_3_2_136_2","doi-asserted-by":"publisher","DOI":"10.1159\/000073973"},{"key":"e_1_3_2_137_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000177475.30281.7f"},{"key":"e_1_3_2_138_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.4.572"},{"key":"e_1_3_2_139_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi028"},{"key":"e_1_3_2_140_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38146.427188.55"},{"key":"e_1_3_2_141_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.99107s6853"},{"key":"e_1_3_2_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-0620(03)00079-3"},{"key":"e_1_3_2_143_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90773-T"},{"key":"e_1_3_2_144_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-199607000-00027"},{"key":"e_1_3_2_145_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.2.119"},{"key":"e_1_3_2_146_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2002.00464.x"},{"key":"e_1_3_2_147_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200262002-00001"},{"key":"e_1_3_2_148_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-120-6-199403150-00002"},{"key":"e_1_3_2_149_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.512632"},{"key":"e_1_3_2_150_2","volume-title":"The Health Consequences of Smoking: A Report of the Surgeon General","author":"US Department of Health and Human Services","year":"2004","unstructured":"US Department of Health and Human Services. The Health Consequences of Smoking: A Report of the Surgeon General. Washington, DC: US Dept of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2004."},{"key":"e_1_3_2_151_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006103.pub3"},{"key":"e_1_3_2_152_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000146.pub3"},{"key":"e_1_3_2_153_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-8-200904210-00009"},{"key":"e_1_3_2_154_2","unstructured":"Prevalence of diabetes and impaired fasting glucose in adults\u2014United States 1999\u20132000. MMWR Morb Mortal Wkly Rep. 2003;52:833\u2013837. Available at: http:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm5235a1.htm. Published September 5 2003. Updated April 7 2004. Accessed August 14 2010."},{"key":"e_1_3_2_155_2","unstructured":"Guide to Clinical Preventive Services: Report of the U. S. Preventive Services Task Force. Baltimore MD: Williams and Wilkins; 1996. Available at: http:\/\/www.ncbi.nlm.nih.gov\/bookshelf\/br.fcgi?book=hscps2ed1996&part=A19920. Accessed October 14 2010."},{"key":"e_1_3_2_156_2","first-page":"1129","article-title":"Prevalence of self-reported cardiovascular disease among persons aged \u226535 years with diabetes\u2014United States, 1997\u20132005","volume":"56","year":"2007","unstructured":"Prevalence of self-reported cardiovascular disease among persons aged \u226535 years with diabetes\u2014United States, 1997\u20132005. MMWR Morb Mortal Wkly Rep. 2007;56:1129\u20131132.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_157_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.2.355"},{"key":"e_1_3_2_158_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706245"},{"key":"e_1_3_2_159_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJR.0b013e3282f335d0"},{"key":"e_1_3_2_160_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-0797"},{"key":"e_1_3_2_161_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)07037-8"},{"key":"e_1_3_2_162_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806470"},{"key":"e_1_3_2_163_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802743"},{"key":"e_1_3_2_164_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802987"},{"key":"e_1_3_2_165_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808431"},{"key":"e_1_3_2_166_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.191305"},{"key":"e_1_3_2_167_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.18.3.361"},{"key":"e_1_3_2_168_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052187"},{"key":"e_1_3_2_169_2","doi-asserted-by":"publisher","DOI":"10.1177\/204748739900600409"},{"key":"e_1_3_2_170_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7160.703"},{"key":"e_1_3_2_171_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540230036032"},{"key":"e_1_3_2_172_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806359"},{"key":"e_1_3_2_173_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)12323-7"},{"key":"e_1_3_2_174_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08089-3"},{"key":"e_1_3_2_175_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.080"},{"key":"e_1_3_2_176_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61303-8"},{"key":"e_1_3_2_177_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.05.057"},{"key":"e_1_3_2_178_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.20.2191"},{"key":"e_1_3_2_179_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328310e0d9"},{"key":"e_1_3_2_180_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001286"},{"key":"e_1_3_2_181_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806182"},{"key":"e_1_3_2_182_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.23.2513"},{"key":"e_1_3_2_183_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12948-0"},{"key":"e_1_3_2_184_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09327-3"},{"key":"e_1_3_2_185_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13636-7"},{"key":"e_1_3_2_186_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16895-5"},{"key":"e_1_3_2_187_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc05-2465"},{"key":"e_1_3_2_188_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.22.2597"},{"key":"e_1_3_2_189_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67667-2"},{"key":"e_1_3_2_190_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001282"},{"key":"e_1_3_2_191_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.623"},{"key":"e_1_3_2_192_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7329.71"},{"key":"e_1_3_2_193_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198904063201405"},{"key":"e_1_3_2_194_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.12.2535"},{"key":"e_1_3_2_195_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyg106"},{"key":"e_1_3_2_196_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000020093.67593.0B"},{"key":"e_1_3_2_197_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000254472.41810.0d"},{"key":"e_1_3_2_198_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000057812.51734.FF"},{"key":"e_1_3_2_199_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.56.suppl_1.i19"},{"key":"e_1_3_2_200_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.2.224"},{"key":"e_1_3_2_201_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.5.929"},{"key":"e_1_3_2_202_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.14.7.1098"},{"key":"e_1_3_2_203_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.498634"},{"key":"e_1_3_2_204_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199708213370802"},{"key":"e_1_3_2_205_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.795666"},{"key":"e_1_3_2_206_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.11.1993"},{"key":"e_1_3_2_207_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.08.022"},{"key":"e_1_3_2_208_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04213-6"},{"key":"e_1_3_2_209_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000258347.19449.0f"},{"key":"e_1_3_2_210_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6946.11"},{"key":"e_1_3_2_211_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000060869.34009.38"},{"key":"e_1_3_2_212_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.1.83"},{"key":"e_1_3_2_213_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.8.1882"},{"key":"e_1_3_2_214_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.21.2729"},{"key":"e_1_3_2_215_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52455.x"},{"key":"e_1_3_2_216_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2007.07.033"},{"key":"e_1_3_2_217_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000102171.91292.dc"},{"key":"e_1_3_2_218_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.10.1484"},{"key":"e_1_3_2_219_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000145615.33955.83"},{"key":"e_1_3_2_220_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.621"},{"key":"e_1_3_2_221_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.3.309"},{"key":"e_1_3_2_222_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000133317.49796.0E"},{"key":"e_1_3_2_223_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.19.2486"},{"key":"e_1_3_2_224_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000147965.52712.fa"},{"key":"e_1_3_2_225_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67394-1"},{"key":"e_1_3_2_226_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70058-4"},{"key":"e_1_3_2_227_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.12.1344"},{"key":"e_1_3_2_228_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04053-8"},{"key":"e_1_3_2_229_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000034508.55617.65"},{"key":"e_1_3_2_230_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80293-5"},{"key":"e_1_3_2_231_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.1.21"},{"key":"e_1_3_2_232_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.23.2828"},{"key":"e_1_3_2_233_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0800742"},{"key":"e_1_3_2_234_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907569"},{"key":"e_1_3_2_235_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.07.023"},{"key":"e_1_3_2_236_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2007.09.002"},{"key":"e_1_3_2_237_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.8.983"},{"key":"e_1_3_2_238_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000267275.68538.8d"},{"key":"e_1_3_2_239_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.501825"},{"key":"e_1_3_2_240_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.946"},{"key":"e_1_3_2_241_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000166053.83476.4a"},{"key":"e_1_3_2_242_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39280.660567.55"},{"key":"e_1_3_2_243_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta9400"},{"key":"e_1_3_2_244_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.22.2864"},{"key":"e_1_3_2_245_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.177292"},{"key":"e_1_3_2_246_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00489-1"},{"key":"e_1_3_2_247_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.07.076"},{"key":"e_1_3_2_248_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0678"},{"key":"e_1_3_2_249_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-5-200909010-00003"},{"key":"e_1_3_2_250_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021328"},{"key":"e_1_3_2_251_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp0903763"},{"key":"e_1_3_2_252_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61343-X"},{"key":"e_1_3_2_253_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-12-200706190-00007"},{"key":"e_1_3_2_254_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0901301"},{"key":"e_1_3_2_255_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60168-3"},{"key":"e_1_3_2_256_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61233-1"},{"key":"e_1_3_2_257_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905561"},{"key":"e_1_3_2_258_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000254622.52483.03"},{"key":"e_1_3_2_259_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022913"},{"key":"e_1_3_2_260_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70536-1"},{"key":"e_1_3_2_261_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68845-4"},{"key":"e_1_3_2_262_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.01.003"},{"key":"e_1_3_2_263_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.653048"},{"key":"e_1_3_2_264_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000181115.59173.42"},{"key":"e_1_3_2_265_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000106480.76217.6f"},{"key":"e_1_3_2_266_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl504"},{"key":"e_1_3_2_267_2","unstructured":"Joint Commission. 2010 National Patient Safety Goals (NPSGs). Available at: http:\/\/www.JointCommission.org\/PatientSafety\/NationalPatientSafetyGoals\/. Accessed October 14 2010."},{"key":"e_1_3_2_268_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1L098"},{"key":"e_1_3_2_269_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000141933.75462.c2"},{"key":"e_1_3_2_270_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.19.2441"},{"key":"e_1_3_2_271_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl488"},{"key":"e_1_3_2_272_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.11.035"},{"key":"e_1_3_2_273_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.11.034"},{"key":"e_1_3_2_274_2","doi-asserted-by":"publisher","DOI":"10.1080\/07853890802089786"},{"key":"e_1_3_2_275_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.002"},{"key":"e_1_3_2_276_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14841-6"},{"key":"e_1_3_2_277_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.6.690"},{"key":"e_1_3_2_278_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe0906886"},{"key":"e_1_3_2_279_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.113.10.e409"},{"key":"e_1_3_2_280_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.11.053"},{"key":"e_1_3_2_281_2","first-page":"261","article-title":"Risk factors profile and clinical outcome of ischemic stroke patients admitted in a Department of Internal Medicine and classified by TOAST classification","volume":"25","author":"Pinto A","year":"2006","unstructured":"Pinto A, Tuttolomondo A, Di Raimondo D, Fernandez P, Licata G . Risk factors profile and clinical outcome of ischemic stroke patients admitted in a Department of Internal Medicine and classified by TOAST classification. Int Angiol. 2006;25:261\u2013267.","journal-title":"Int Angiol"},{"key":"e_1_3_2_282_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.1999.660677.x"},{"key":"e_1_3_2_283_2","doi-asserted-by":"publisher","DOI":"10.4065\/84.1.43"},{"key":"e_1_3_2_284_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000138790.14877.7D"},{"key":"e_1_3_2_285_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.6.642"},{"key":"e_1_3_2_286_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612193352501"},{"key":"e_1_3_2_287_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701233360403"},{"key":"e_1_3_2_288_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199209033271001"},{"key":"e_1_3_2_289_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)89163-1"},{"key":"e_1_3_2_290_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.02.013"},{"key":"e_1_3_2_291_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.001"},{"key":"e_1_3_2_292_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.009"},{"key":"e_1_3_2_293_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.007"},{"key":"e_1_3_2_294_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.32.1.26"},{"key":"e_1_3_2_295_2","first-page":"341","article-title":"A study of stroke associated with prolapsed mitral valve","volume":"23","author":"Hanson MR","year":"1978","unstructured":"Hanson MR, Hodgeman JR, Conomy JP . A study of stroke associated with prolapsed mitral valve. Neurology. 1978;23:341.","journal-title":"Neurology"},{"key":"e_1_3_2_296_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199208063270602"},{"key":"e_1_3_2_297_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.593418"},{"key":"e_1_3_2_298_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.115790"},{"key":"e_1_3_2_299_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010082"},{"key":"e_1_3_2_300_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960220605"},{"key":"e_1_3_2_301_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512143332407"},{"key":"e_1_3_2_302_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.2.398"},{"key":"e_1_3_2_303_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.063"},{"key":"e_1_3_2_304_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp043981"},{"key":"e_1_3_2_305_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.8.1172"},{"key":"e_1_3_2_306_2","doi-asserted-by":"publisher","DOI":"10.4065\/81.5.602"},{"key":"e_1_3_2_307_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.044"},{"key":"e_1_3_2_308_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000017498.88393.44"},{"key":"e_1_3_2_309_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.801753"},{"key":"e_1_3_2_310_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412013312202"},{"key":"e_1_3_2_311_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(00)90243-6"},{"key":"e_1_3_2_312_2","doi-asserted-by":"publisher","DOI":"10.4065\/81.5.609"},{"key":"e_1_3_2_313_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00454-9"},{"key":"e_1_3_2_314_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02336-7"},{"key":"e_1_3_2_315_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02848-6"},{"key":"e_1_3_2_316_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.07.014"},{"key":"e_1_3_2_317_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520420037035"},{"key":"e_1_3_2_318_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16146-1"},{"key":"e_1_3_2_319_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301283280401"},{"key":"e_1_3_2_320_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.9.1281"},{"key":"e_1_3_2_321_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(96)70277-X"},{"key":"e_1_3_2_322_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1052-3057(10)80013-8"},{"key":"e_1_3_2_323_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.8.1009"},{"key":"e_1_3_2_324_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000141426.63959.cc"},{"key":"e_1_3_2_325_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.6.1046"},{"key":"e_1_3_2_326_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.4.524"},{"key":"e_1_3_2_327_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.21.8.860"},{"key":"e_1_3_2_328_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1973.01350230081016"},{"key":"e_1_3_2_329_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.08.030"},{"key":"e_1_3_2_330_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2003.09.023"},{"key":"e_1_3_2_331_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2007.43"},{"key":"e_1_3_2_332_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040127"},{"key":"e_1_3_2_333_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0708028"},{"key":"e_1_3_2_334_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2005.04.023"},{"key":"e_1_3_2_335_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.01.008"},{"key":"e_1_3_2_336_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-009-0024-6"},{"key":"e_1_3_2_337_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0912321"},{"key":"e_1_3_2_338_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-12-200712180-00005"},{"key":"e_1_3_2_339_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.556068"},{"key":"e_1_3_2_340_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.109.561837"},{"key":"e_1_3_2_341_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.578856"},{"key":"e_1_3_2_342_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000141706.50170.a7"},{"key":"e_1_3_2_343_2","first-page":"599","volume-title":"Sickle Cell Disease: Basic Principles and Clinical Practice","author":"Adams R","year":"1994","unstructured":"Adams R . In: , Embury S , ed. Sickle Cell Disease: Basic Principles and Clinical Practice. New York, NY: Raven Press;1994:599\u2013621."},{"issue":"6","key":"e_1_3_2_344_2","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1542\/peds.97.6.864","article-title":"Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease","volume":"97","author":"Armstrong FD","year":"1996","unstructured":"Armstrong FD, Thompson RJ, Wang W, Zimmerman R, Pegelow CH, Miller S, Moser F, Bello J, Hurtig A, Vass K . Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics. 1996;97(6 Pt 1):864\u2013870.","journal-title":"Pediatrics"},{"key":"e_1_3_2_345_2","first-page":"288","article-title":"Cerebrovascular accidents in sickle cell disease: rates and risk factors","volume":"91","author":"Ohene-Frempong K","year":"1998","unstructured":"Ohene-Frempong K, Weiner SJ, Sleeper LA, Miller ST, Embury S, Moohr JW, Wethers DL, Pegelow CH, Gill FM . Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288\u2013294.","journal-title":"Blood"},{"key":"e_1_3_2_346_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199202273260905"},{"key":"e_1_3_2_347_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410420505"},{"key":"e_1_3_2_348_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807023390102"},{"key":"e_1_3_2_349_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06193.x"},{"key":"e_1_3_2_350_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-004-1282-9"},{"key":"e_1_3_2_351_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21430"},{"key":"e_1_3_2_352_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21677"},{"key":"e_1_3_2_353_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04821-2"},{"key":"e_1_3_2_354_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-005-1419-5"},{"key":"e_1_3_2_355_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200308000-00007"},{"key":"e_1_3_2_356_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-03-143891"},{"key":"e_1_3_2_357_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2771"},{"key":"e_1_3_2_358_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1533"},{"key":"e_1_3_2_359_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.483115"},{"key":"e_1_3_2_360_2","doi-asserted-by":"publisher","DOI":"10.1159\/000089592"},{"key":"e_1_3_2_361_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000230150.39429.8e"},{"key":"e_1_3_2_362_2","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1182\/blood.V81.5.1109.bloodjournal8151109","article-title":"Transfusion management of sickle cell disease","volume":"81","author":"Wayne AS","year":"1993","unstructured":"Wayne AS, Kevy SV, Nathan DG . Transfusion management of sickle cell disease. Blood. 1993;81:1109\u20131123.","journal-title":"Blood"},{"key":"e_1_3_2_363_2","volume-title":"Paper presented at: 23rd Annual Meeting of the National Sickle Cell Disease Program","author":"Vichinsky E","unstructured":"Vichinsky E, Luban N, Wright E, Olivieri N, Driscoll C, Pegelow C, Files B, Adams RJ Prospective cell phenotype matching in STOP\u2014a multi-center transfusion trial. Paper presented at: 23rd Annual Meeting of the National Sickle Cell Disease Program; March 1999; San Francisco, CA."},{"key":"e_1_3_2_364_2","unstructured":"Clinical Alert from the National Heart Lung and Blood Institute. NHLBI website. Available at: http:\/\/www.nhlbi.nih.gov\/health\/prof\/blood\/sickle\/clinical-alert-scd.htm. Published December 5 2004. Accessed August 14 2010."},{"key":"e_1_3_2_365_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050460"},{"key":"e_1_3_2_366_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.117580"},{"key":"e_1_3_2_367_2","unstructured":"Silent Infarct Transfusion (SIT) Study. Stroke Trials Registry website. Available at: http:\/\/www.strokecenter.org\/trials\/TrialDetail.aspx?tid=627. Updated June 8 2010. Accessed August 14 2010."},{"key":"e_1_3_2_368_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-079665"},{"key":"e_1_3_2_369_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-07-2704"},{"key":"e_1_3_2_370_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20819"},{"key":"e_1_3_2_371_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-11-057893"},{"key":"e_1_3_2_372_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.3.321"},{"key":"e_1_3_2_373_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.1.47"},{"key":"e_1_3_2_374_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.7.605"},{"key":"e_1_3_2_375_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010534"},{"key":"e_1_3_2_376_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.14.1701"},{"key":"e_1_3_2_377_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.107.181546"},{"key":"e_1_3_2_378_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.594077"},{"key":"e_1_3_2_379_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1112062"},{"key":"e_1_3_2_380_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.13.1465"},{"key":"e_1_3_2_381_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.8.861"},{"key":"e_1_3_2_382_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2006.01.012"},{"key":"e_1_3_2_383_2","doi-asserted-by":"publisher","DOI":"10.1080\/13697130500042417"},{"key":"e_1_3_2_384_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062462"},{"key":"e_1_3_2_385_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.518621"},{"key":"e_1_3_2_386_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.23.joc60074"},{"key":"e_1_3_2_387_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0800743"},{"key":"e_1_3_2_388_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.5.935"},{"key":"e_1_3_2_389_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6883.956"},{"key":"e_1_3_2_390_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.1.72"},{"key":"e_1_3_2_391_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.7.741"},{"key":"e_1_3_2_392_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7175.13"},{"key":"e_1_3_2_393_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000015345.61324.3f"},{"key":"e_1_3_2_394_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01442.x"},{"key":"e_1_3_2_395_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1657546"},{"key":"e_1_3_2_396_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.3.483"},{"key":"e_1_3_2_397_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.11.2277"},{"key":"e_1_3_2_398_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.9.1702"},{"key":"e_1_3_2_399_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.52.12.775"},{"key":"e_1_3_2_400_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000129789.58837.e4"},{"key":"e_1_3_2_401_2","unstructured":"Deleted in proof."},{"key":"e_1_3_2_402_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000077925.16041.6b"},{"key":"e_1_3_2_403_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2000.00035.x"},{"key":"e_1_3_2_404_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000202568.01167.B6"},{"key":"e_1_3_2_405_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68069-0"},{"key":"e_1_3_2_406_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.13.1233"},{"key":"e_1_3_2_407_2","author":"US Dept of Health and Human Services and US Dept of Agriculture","year":"2005","unstructured":"US Dept of Health and Human Services and US Dept of Agriculture. Dietary Guidelines for Americans, 2005. 6th ed. Washington, DC: US Government Printing Office; 2005.","journal-title":"Dietary Guidelines for Americans"},{"key":"e_1_3_2_408_2","first-page":"23","article-title":"Salt intake and stroke: a possible direct effect","volume":"6","author":"Perry IJ","year":"1992","unstructured":"Perry IJ, Beevers DG . Salt intake and stroke: a possible direct effect. J Hum Hypertens. 1992;6:23\u201325.","journal-title":"J Hum Hypertens"},{"key":"e_1_3_2_409_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.21.2027"},{"key":"e_1_3_2_410_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000130425.50441.b0"},{"key":"e_1_3_2_411_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.12.1198"},{"key":"e_1_3_2_412_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198701293160502"},{"key":"e_1_3_2_413_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/83.6.1289"},{"key":"e_1_3_2_414_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.6.655"},{"key":"e_1_3_2_415_2","first-page":"S363","article-title":"Potassium prevents death from strokes in hypertensive rats without lowering blood pressure","volume":"2","author":"Tobian L","year":"1984","unstructured":"Tobian L, Lange JM, Ulm KM, Wold LJ, Iwai J . Potassium prevents death from strokes in hypertensive rats without lowering blood pressure. J HypertensSuppl. 1984;2:S363\u2013366.","journal-title":"J HypertensSuppl"},{"key":"e_1_3_2_416_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200106000-00009"},{"key":"e_1_3_2_417_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91852-7"},{"key":"e_1_3_2_418_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101043440101"},{"key":"e_1_3_2_419_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-12-200112180-00005"},{"key":"e_1_3_2_420_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540440058033"},{"key":"e_1_3_2_421_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.33.1.18"},{"key":"e_1_3_2_422_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704173361601"},{"key":"e_1_3_2_423_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.19.2455"},{"key":"e_1_3_2_424_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)98858-6"},{"key":"e_1_3_2_425_2","volume-title":"Dietary Reference Intakes: Water, Potassium, Sodium, Chloride, and Sulfate","author":"Institute of Medicine","year":"2004","unstructured":"Institute of Medicine. Dietary Reference Intakes: Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: National Academies Press; 2004."},{"key":"e_1_3_2_426_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000130426.52064.09"},{"key":"e_1_3_2_427_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7418.777"},{"key":"e_1_3_2_428_2","unstructured":"Physical Activity Guidelines Advisory Committee Report 2008. Washington DC: US Dept of Health and Human Services; 2008. Available at: http:\/\/www.health.gov\/paguidelines\/. Accessed August 14 2010."},{"key":"e_1_3_2_429_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000091843.02517.9d"},{"key":"e_1_3_2_430_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyh168"},{"key":"e_1_3_2_431_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008829"},{"key":"e_1_3_2_432_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.2.380"},{"key":"e_1_3_2_433_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1991.00400060077013"},{"key":"e_1_3_2_434_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540030039029"},{"key":"e_1_3_2_435_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)80007-4"},{"key":"e_1_3_2_436_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90111-D"},{"key":"e_1_3_2_437_2","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/50A.1.M12"},{"key":"e_1_3_2_438_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199605163342004"},{"key":"e_1_3_2_439_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/68.4.899"},{"key":"e_1_3_2_440_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.13.1549"},{"key":"e_1_3_2_441_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.20.2401"},{"key":"e_1_3_2_442_2","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxm007"},{"key":"e_1_3_2_443_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60318-4"},{"key":"e_1_3_2_444_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26847"},{"key":"e_1_3_2_445_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.5.701"},{"key":"e_1_3_2_446_2","doi-asserted-by":"publisher","DOI":"10.2302\/kjm.53.7"},{"key":"e_1_3_2_447_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000075294.98582.2F"},{"key":"e_1_3_2_448_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008892"},{"key":"e_1_3_2_449_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.0000094221.86888.ae"},{"key":"e_1_3_2_450_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.310.6983.830"},{"key":"e_1_3_2_451_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38302.504063.8F"},{"key":"e_1_3_2_452_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000154528.21485.3A"},{"key":"e_1_3_2_453_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a636"},{"key":"e_1_3_2_454_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.488395"},{"key":"e_1_3_2_455_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.9.1366"},{"key":"e_1_3_2_456_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000325918.48056.75"},{"key":"e_1_3_2_457_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)92944-3"},{"key":"e_1_3_2_458_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198805053181802"},{"key":"e_1_3_2_459_2","unstructured":"Deleted in proof."},{"key":"e_1_3_2_460_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.8.1622"},{"key":"e_1_3_2_461_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/116.1.187"},{"key":"e_1_3_2_462_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.019638"},{"key":"e_1_3_2_463_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.107.727271"},{"key":"e_1_3_2_464_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21504"},{"key":"e_1_3_2_465_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67402-8"},{"key":"e_1_3_2_466_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.21.2709"},{"key":"e_1_3_2_467_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66378-7"},{"key":"e_1_3_2_468_2","first-page":"15","article-title":"Monitoring central venous pressure: principles, procedures and problems","volume":"72","author":"Kay G","year":"1976","unstructured":"Kay G, Kearns P . Monitoring central venous pressure: principles, procedures and problems. Can Nurse. 1976;72:15\u201317.","journal-title":"Can Nurse"},{"key":"e_1_3_2_469_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.10.1195"},{"key":"e_1_3_2_470_2","doi-asserted-by":"publisher","DOI":"10.1210\/er.2008-0024"},{"key":"e_1_3_2_471_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.6.1147"},{"key":"e_1_3_2_472_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.8.1498"},{"key":"e_1_3_2_473_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afl094"},{"key":"e_1_3_2_474_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.6.1157"},{"key":"e_1_3_2_475_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.12.2936"},{"key":"e_1_3_2_476_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2007.10.007"},{"key":"e_1_3_2_477_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.9.1860"},{"key":"e_1_3_2_478_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.7.1329"},{"key":"e_1_3_2_479_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.522557"},{"key":"e_1_3_2_480_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000221766.73692.0b"},{"key":"e_1_3_2_481_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.499830"},{"key":"e_1_3_2_482_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.9.1780"},{"key":"e_1_3_2_483_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000108926.04022.0C"},{"key":"e_1_3_2_484_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000169935.35394.38"},{"key":"e_1_3_2_485_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000206458.58142.f3"},{"key":"e_1_3_2_486_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000169945.75911.33"},{"key":"e_1_3_2_487_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000204354.06965.44"},{"key":"e_1_3_2_488_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.1.106"},{"key":"e_1_3_2_489_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.11.2745"},{"key":"e_1_3_2_490_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2007.03.005"},{"key":"e_1_3_2_491_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.041"},{"key":"e_1_3_2_492_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69292-1"},{"key":"e_1_3_2_493_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198610233151701"},{"key":"e_1_3_2_494_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.11.2307"},{"key":"e_1_3_2_495_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01824-0"},{"key":"e_1_3_2_496_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2001.961217434.x"},{"key":"e_1_3_2_497_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.6.1033"},{"key":"e_1_3_2_498_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911183412101"},{"key":"e_1_3_2_499_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.12.004"},{"key":"e_1_3_2_500_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000195048.86810.5b"},{"key":"e_1_3_2_501_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.3.339"},{"key":"e_1_3_2_502_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000124459.33597.00"},{"key":"e_1_3_2_503_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.32.1.77"},{"key":"e_1_3_2_504_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.1.53"},{"key":"e_1_3_2_505_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198808043190503"},{"key":"e_1_3_2_506_2","doi-asserted-by":"publisher","DOI":"10.1159\/000054808"},{"key":"e_1_3_2_507_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.5.579"},{"key":"e_1_3_2_508_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-008-1031-y"},{"key":"e_1_3_2_509_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.537704"},{"key":"e_1_3_2_510_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.07.103"},{"key":"e_1_3_2_511_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(03)00473-9"},{"key":"e_1_3_2_512_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.alc.0000183011.86768.61"},{"key":"e_1_3_2_513_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.16.10.1285"},{"key":"e_1_3_2_514_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.547844"},{"key":"e_1_3_2_515_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1511"},{"key":"e_1_3_2_516_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2008.03.132"},{"key":"e_1_3_2_517_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.13.1403"},{"key":"e_1_3_2_518_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21194"},{"key":"e_1_3_2_519_2","unstructured":"US Preventive Services Task Force. Screening and behavioral counseling interventions in primary care to reduce alcohol misuse: recommendation statement. Rockville MD: Agency for Healthcare Research and Quality. Available at: http:\/\/www.uspreventiveservicestaskforce.org\/uspstf\/uspsdrin.htm. Published April 2004. Accessed October 14 2010."},{"key":"e_1_3_2_520_2","author":"US Dept of Health and Human Services and US Dept of Agriculture","year":"2005","unstructured":"US Dept of Health and Human Services and US Dept of Agriculture. Dietary Guidelines for Americans, 2005. Available at: http:\/\/www.health.gov\/dietaryguidelines. Accessed August 14, 2010.","journal-title":"Dietary Guidelines for Americans"},{"key":"e_1_3_2_521_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.176158"},{"key":"e_1_3_2_522_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra023160"},{"key":"e_1_3_2_523_2","volume-title":"Neurological Aspects of Substance Abuse","author":"Brust JC","year":"2004","unstructured":"Brust JC . Neurological Aspects of Substance Abuse. II ed. Philadelphia, PA: Butterworth-Heinemann; 2004."},{"key":"e_1_3_2_524_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.5.376"},{"key":"e_1_3_2_525_2","doi-asserted-by":"publisher","DOI":"10.1080\/02688690050175247"},{"key":"e_1_3_2_526_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.paf.0000137206.16785.2f"},{"key":"e_1_3_2_527_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2000.00045.x"},{"key":"e_1_3_2_528_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(99)00009-8"},{"key":"e_1_3_2_529_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.16.1925"},{"key":"e_1_3_2_530_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-11-821"},{"key":"e_1_3_2_531_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.4.890"},{"key":"e_1_3_2_532_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199009133231102"},{"key":"e_1_3_2_533_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199811000-00005"},{"key":"e_1_3_2_534_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.6.1688"},{"key":"e_1_3_2_535_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.64.4.495"},{"key":"e_1_3_2_536_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2007.12.003"},{"key":"e_1_3_2_537_2","unstructured":"US Preventive Services Task Force. Screening for Illicit Drug Use. Rockville MD: Agency for Healthcare Research and Quality. Available at: http:\/\/www.ahrq.gov\/clinic\/uspstf\/uspsdrug.htm. Published in January 2008. Accessed August 14 2010."},{"issue":"6","key":"e_1_3_2_538_2","first-page":"75","article-title":"Snoring, sleep apnea syndrome, and stroke","volume":"42","author":"Palomaki H","year":"1992","unstructured":"Palomaki H, Partinen M, Erkinjuntti T, Kaste M . Snoring, sleep apnea syndrome, and stroke. Neurology. 1992;42(suppl 6):75\u201381.","journal-title":"Neurology"},{"key":"e_1_3_2_539_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92625-X"},{"key":"e_1_3_2_540_2","first-page":"1207","article-title":"Heavy snoring as a cause of carotid artery atherosclerosis","volume":"31","author":"Lee SA","year":"2008","unstructured":"Lee SA, Amis TC, Byth K, Larcos G, Kairaitis K, Robinson TD, Wheatley JR . Heavy snoring as a cause of carotid artery atherosclerosis. Sleep. 2008;31:1207\u20131213.","journal-title":"Sleep"},{"key":"e_1_3_2_541_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0962-1105.2003.00371.x"},{"key":"e_1_3_2_542_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"},{"key":"e_1_3_2_543_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000236560.15735.0f"},{"key":"e_1_3_2_544_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200505-702OC"},{"key":"e_1_3_2_545_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.783290"},{"key":"e_1_3_2_546_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-004-0032-6"},{"key":"e_1_3_2_547_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200302000-00012"},{"key":"e_1_3_2_548_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-5231(03)00027-3"},{"key":"e_1_3_2_549_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.14.1829"},{"key":"e_1_3_2_550_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005113421901"},{"key":"e_1_3_2_551_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7233.479"},{"key":"e_1_3_2_552_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200112000-00022"},{"key":"e_1_3_2_553_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90013-9"},{"key":"e_1_3_2_554_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-199606000-00011"},{"key":"e_1_3_2_555_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(93)90454-K"},{"key":"e_1_3_2_556_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.5.1537"},{"key":"e_1_3_2_557_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.10.056"},{"key":"e_1_3_2_558_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn214"},{"key":"e_1_3_2_559_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.3.879"},{"key":"e_1_3_2_560_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.12.007"},{"key":"e_1_3_2_561_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000136587.68725.8E"},{"key":"e_1_3_2_562_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2004.02.002"},{"key":"e_1_3_2_563_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1000862"},{"key":"e_1_3_2_564_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.060"},{"key":"e_1_3_2_565_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200608-1141OC"},{"key":"e_1_3_2_566_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000042706.47107.7a"},{"key":"e_1_3_2_567_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/27.5.934"},{"key":"e_1_3_2_568_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07445-7"},{"key":"e_1_3_2_569_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01136.x"},{"key":"e_1_3_2_570_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200611-1588OC"},{"key":"e_1_3_2_571_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199804093381507"},{"key":"e_1_3_2_572_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03510220049033"},{"key":"e_1_3_2_573_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530130055028"},{"key":"e_1_3_2_574_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540460039030"},{"key":"e_1_3_2_575_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.5.437"},{"key":"e_1_3_2_576_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-131-5-199909070-00006"},{"key":"e_1_3_2_577_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.516575"},{"key":"e_1_3_2_578_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.12.2473"},{"key":"e_1_3_2_579_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000060203.58958.35"},{"key":"e_1_3_2_580_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.87.4.1107"},{"key":"e_1_3_2_581_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.18.2383"},{"key":"e_1_3_2_582_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199502023320502"},{"key":"e_1_3_2_583_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2004.06.003"},{"key":"e_1_3_2_584_2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X08092102"},{"key":"e_1_3_2_585_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvbaha.108.162743"},{"key":"e_1_3_2_586_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.16.2015"},{"key":"e_1_3_2_587_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7374.1202"},{"key":"e_1_3_2_588_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000127813.12854.9c"},{"key":"e_1_3_2_589_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000106762.55994.86"},{"key":"e_1_3_2_590_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000169934.96354.3a"},{"key":"e_1_3_2_591_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.524934"},{"key":"e_1_3_2_592_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.526798"},{"key":"e_1_3_2_593_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2261-8-24"},{"key":"e_1_3_2_594_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.064"},{"key":"e_1_3_2_595_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055227"},{"key":"e_1_3_2_596_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.7.795"},{"key":"e_1_3_2_597_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.17.2027"},{"key":"e_1_3_2_598_2","doi-asserted-by":"publisher","DOI":"10.1159\/000093680"},{"key":"e_1_3_2_599_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000110181.64655.6C"},{"key":"e_1_3_2_600_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.5.565"},{"key":"e_1_3_2_601_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060900"},{"key":"e_1_3_2_602_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.529503"},{"key":"e_1_3_2_603_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.22.2720"},{"key":"e_1_3_2_604_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60854-X"},{"key":"e_1_3_2_605_2","doi-asserted-by":"publisher","DOI":"10.1097\/00041433-200308000-00004"},{"key":"e_1_3_2_606_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.10.1082"},{"key":"e_1_3_2_607_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(00)00427-5"},{"key":"e_1_3_2_608_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M302780200"},{"key":"e_1_3_2_609_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa001066"},{"key":"e_1_3_2_610_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.08.036"},{"key":"e_1_3_2_611_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000222666.21482.b6"},{"key":"e_1_3_2_612_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520400039041"},{"key":"e_1_3_2_613_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvbaha.108.169292"},{"key":"e_1_3_2_614_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.9.1582"},{"key":"e_1_3_2_615_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.4.653"},{"key":"e_1_3_2_616_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.106.480657"},{"key":"e_1_3_2_617_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.10.2069"},{"key":"e_1_3_2_618_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22663"},{"key":"e_1_3_2_619_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199907000-00001"},{"key":"e_1_3_2_620_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-12-997"},{"key":"e_1_3_2_621_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.32.8.1701"},{"key":"e_1_3_2_622_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000117575.48205.2d"},{"key":"e_1_3_2_623_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.5.576"},{"key":"e_1_3_2_624_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170176"},{"key":"e_1_3_2_625_2","doi-asserted-by":"publisher","DOI":"10.1159\/000048623"},{"key":"e_1_3_2_626_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-11-3334"},{"key":"e_1_3_2_627_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000031927.25510.d1"},{"key":"e_1_3_2_628_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F"},{"key":"e_1_3_2_629_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(05)70225-8"},{"key":"e_1_3_2_630_2","first-page":"152","volume-title":"A Primer on Stroke Prevention and Treatment: An Overview Based on AHA\/ASA Guidelines","author":"Becker R","year":"2009","unstructured":"Becker R, Chan M, Shah SH, Levine SR . Coagulopathy and stroke: evaluation and treatment. In: , Goldstein LB , ed. A Primer on Stroke Prevention and Treatment: An Overview Based on AHA\/ASA Guidelines. Dallas, TX: American Heart Association;2009:152\u2013169."},{"key":"e_1_3_2_631_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000046457.54037.cc"},{"key":"e_1_3_2_632_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.10.042"},{"key":"e_1_3_2_633_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.19.2352"},{"key":"e_1_3_2_634_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.4.397"},{"key":"e_1_3_2_635_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-145-11-200612050-00005"},{"key":"e_1_3_2_636_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.3.282"},{"key":"e_1_3_2_637_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2007.10.001"},{"key":"e_1_3_2_638_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta10110"},{"key":"e_1_3_2_639_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2005.05.021"},{"key":"e_1_3_2_640_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.011"},{"key":"e_1_3_2_641_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000154553.12214.cd"},{"key":"e_1_3_2_642_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60992-0"},{"key":"e_1_3_2_643_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.513259"},{"key":"e_1_3_2_644_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000052939.59093.45"},{"key":"e_1_3_2_645_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704033361401"},{"key":"e_1_3_2_646_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.8.731"},{"key":"e_1_3_2_647_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0807646"},{"key":"e_1_3_2_648_2","doi-asserted-by":"publisher","DOI":"10.1161\/hs1101.098151"},{"key":"e_1_3_2_649_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.09.037"},{"key":"e_1_3_2_650_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.06.011"},{"key":"e_1_3_2_651_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.052456"},{"key":"e_1_3_2_652_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.018101"},{"key":"e_1_3_2_653_2","first-page":"36","article-title":"Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis","volume":"30","author":"Wolfe F","year":"2003","unstructured":"Wolfe F, Freundlich B, Straus WL . Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis. J Rheumatol. 2003;30:36\u201340.","journal-title":"J Rheumatol"},{"key":"e_1_3_2_654_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200110)44:10<2331::AID-ART395>3.0.CO;2-I"},{"key":"e_1_3_2_655_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199901)42:1<51::AID-ANR7>3.0.CO;2-D"},{"key":"e_1_3_2_656_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-4-200602210-00006"},{"key":"e_1_3_2_657_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.06.010"},{"key":"e_1_3_2_658_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.06.009"},{"key":"e_1_3_2_659_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.11.4095"},{"key":"e_1_3_2_660_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12706-7"},{"key":"e_1_3_2_661_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000054613.57105.06"},{"key":"e_1_3_2_662_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.04.044"},{"key":"e_1_3_2_663_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70233-6"},{"key":"e_1_3_2_664_2","doi-asserted-by":"publisher","DOI":"10.1159\/000172796"},{"key":"e_1_3_2_665_2","doi-asserted-by":"publisher","DOI":"10.1161\/hs0202.102328"},{"key":"e_1_3_2_666_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025028"},{"key":"e_1_3_2_667_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.10.015"},{"key":"e_1_3_2_668_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.178242"},{"key":"e_1_3_2_669_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-2-200201150-00016"},{"key":"e_1_3_2_670_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000020190.45892.75"},{"key":"e_1_3_2_671_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6921.81"},{"key":"e_1_3_2_672_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.3.326"},{"key":"e_1_3_2_673_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1840"},{"key":"e_1_3_2_674_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050613"},{"key":"e_1_3_2_675_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00387-3"},{"key":"e_1_3_2_676_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7304.75"},{"key":"e_1_3_2_677_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.1.40"},{"key":"e_1_3_2_678_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.8.1049"},{"key":"e_1_3_2_679_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7375.1271"},{"key":"e_1_3_2_680_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00434-6"},{"key":"e_1_3_2_681_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.7.1341"},{"key":"e_1_3_2_682_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.104.4.491"},{"key":"e_1_3_2_683_2","first-page":"248","article-title":"Cardiovascular risk: its assessment in clinical practice","volume":"58","author":"Wilson SL","year":"2001","unstructured":"Wilson SL, Poulter NR . Cardiovascular risk: its assessment in clinical practice. Br J Biomed Sci. 2001;58:248\u2013251.","journal-title":"Br J Biomed Sci"},{"key":"e_1_3_2_684_2","doi-asserted-by":"publisher","DOI":"10.1197\/j.aem.2006.07.011"},{"key":"e_1_3_2_685_2","first-page":"1","article-title":"National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary","author":"Pitts SR","year":"2008","unstructured":"Pitts SR, Niska RW, Xu J, Burt CW . National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary. Natl Health Stat Report. 2008:1\u201338.","journal-title":"Natl Health Stat Report"},{"key":"e_1_3_2_686_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2000.tb02098.x"},{"key":"e_1_3_2_687_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2008.00055.x"},{"key":"e_1_3_2_688_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000031796.52748.A5"},{"key":"e_1_3_2_689_2","first-page":"345","article-title":"Emergency physicians and preventive medicine","volume":"149","author":"Marsden C","year":"1988","unstructured":"Marsden C, Pinell MC, Joyce SM . Emergency physicians and preventive medicine. West J Med. 1988;149:345.","journal-title":"West J Med"},{"key":"e_1_3_2_690_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2007.03.032"},{"key":"e_1_3_2_691_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-008-0661-6"},{"key":"e_1_3_2_692_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2005.01674.x"},{"key":"e_1_3_2_693_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-1-199407010-00008"},{"key":"e_1_3_2_694_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2007.03.007"},{"key":"e_1_3_2_695_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000035260.70403.88"},{"key":"e_1_3_2_696_2","doi-asserted-by":"publisher","DOI":"10.1071\/AH010061"},{"key":"e_1_3_2_697_2","first-page":"300","article-title":"Annual smoking-attributable mortality, years of potential life lost, and economic costs\u2013United States, 1995\u20131999","volume":"51","year":"2002","unstructured":"Annual smoking-attributable mortality, years of potential life lost, and economic costs\u2013United States, 1995\u20131999. MMWR Morb Mortal Wkly Rep. 2002;51:300\u2013303.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_698_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2006.02.018"},{"key":"e_1_3_2_699_2","doi-asserted-by":"publisher","DOI":"10.1197\/aemj.9.6.627"},{"key":"e_1_3_2_700_2","article-title":"Effects of an intervention brochure on emergency department patients' safe alcohol use and knowledge","author":"Wang TC","year":"2008","unstructured":"Wang TC, Kyriacou DN, Wolf MS . Effects of an intervention brochure on emergency department patients' safe alcohol use and knowledge. J Emerg Med. 2008 May 5. [Epub ahead of print.]","journal-title":"J Emerg Med"},{"key":"e_1_3_2_701_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2007.06.486"},{"key":"e_1_3_2_702_2","doi-asserted-by":"publisher","DOI":"10.1300\/J465v28n04_01"},{"key":"e_1_3_2_703_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(00)90041-X"},{"key":"e_1_3_2_704_2","doi-asserted-by":"publisher","DOI":"10.1093\/heapro\/17.2.179"},{"key":"e_1_3_2_705_2","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.18.5.401"},{"key":"e_1_3_2_706_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.10.1899"},{"key":"e_1_3_2_707_2","doi-asserted-by":"publisher","DOI":"10.1136\/qhc.11.1.6"},{"key":"e_1_3_2_708_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.01.032"},{"key":"e_1_3_2_709_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.10.007"},{"key":"e_1_3_2_710_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.0000200692.23410.c9"},{"key":"e_1_3_2_711_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj124"},{"key":"e_1_3_2_712_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.3.335"},{"key":"e_1_3_2_713_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530090032018"},{"key":"e_1_3_2_714_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000409.pub2"},{"key":"e_1_3_2_715_2","doi-asserted-by":"publisher","DOI":"10.1136\/qshc.2006.019778"},{"key":"e_1_3_2_716_2","doi-asserted-by":"publisher","DOI":"10.1136\/jamia.1996.97084513"},{"key":"e_1_3_2_717_2","first-page":"W242","article-title":"Process evaluation of a tailored multifaceted approach to changing family physician practice patterns improving preventive care","volume":"50","author":"Baskerville NB","year":"2001","unstructured":"Baskerville NB, Hogg W, Lemelin J . Process evaluation of a tailored multifaceted approach to changing family physician practice patterns improving preventive care. J Fam Pract. 2001;50:W242\u2013249.","journal-title":"J Fam Pract"},{"key":"e_1_3_2_718_2","first-page":"934","article-title":"Multifaceted support to improve preventive cardiovascular care: a nationwide, controlled trial in general practice","volume":"53","author":"Frijling B","year":"2003","unstructured":"Frijling B, Hulscher ME, van Leest LA, Braspenning JC, van den Hoogen H, Drenthen AJ, Grol RP . Multifaceted support to improve preventive cardiovascular care: a nationwide, controlled trial in general practice. Br J Gen Pract. 2003;53:934\u2013941.","journal-title":"Br J Gen Pract"},{"key":"e_1_3_2_719_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-9-200205070-00006"},{"key":"e_1_3_2_720_2","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzi004"},{"key":"e_1_3_2_721_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2008.04.008"},{"key":"e_1_3_2_722_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2007.101"},{"key":"e_1_3_2_723_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000171706.68756.b7"},{"key":"e_1_3_2_724_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.496570"},{"key":"e_1_3_2_725_2","first-page":"767","article-title":"Improving delivery of preventive health care with the comprehensive annotated reminder tool (CART)","volume":"50","author":"Shannon KC","year":"2001","unstructured":"Shannon KC, Sinacore JM, Bennett SG, Joshi AM, Sherin KM, Deitrich A . Improving delivery of preventive health care with the comprehensive annotated reminder tool (CART). J Fam Pract. 2001;50:767\u2013771.","journal-title":"J Fam Pract"},{"key":"e_1_3_2_726_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-4-200702200-00008"},{"key":"e_1_3_2_727_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.9.1366"},{"key":"e_1_3_2_728_2","first-page":"1221","article-title":"Cigarette smoking among adults\u2013United States, 2007","volume":"57","year":"2008","unstructured":"Cigarette smoking among adults\u2013United States, 2007. MMWR Morb Mortal Wkly Rep. 2008;57:1221\u20131226.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_729_2","volume-title":"Heart Disease and Stroke Statistics: 2009 Update","year":"2009","unstructured":"Heart Disease and Stroke Statistics: 2009 Update. Dallas, TX: American Heart Association; 2009."},{"key":"e_1_3_2_730_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000177495.45580.f1"},{"key":"e_1_3_2_731_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.16.1983"},{"key":"e_1_3_2_732_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-140-3-200402030-00009"},{"key":"e_1_3_2_733_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2003.08.006"},{"key":"e_1_3_2_734_2","unstructured":"Deleted in proof."},{"key":"e_1_3_2_735_2","unstructured":"Ogden CL Carroll MD McDowell MA Flegal KM . Obesity among adults in the United States\u2014no change since 2003\u20132004. NCHS data brief no 1. Hyattsville MD: National Center for Health Statistics; 2007."},{"key":"e_1_3_2_736_2","unstructured":"Deleted in proof."},{"key":"e_1_3_2_737_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.2.299"}],"updated-by":[{"DOI":"10.1161\/str.0b013e31820c799f","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000}}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STR.0b013e3181fcb238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T08:02:25Z","timestamp":1715587345000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STR.0b013e3181fcb238"}},"subtitle":["A Guideline for Healthcare Professionals From the American Heart Association\/American Stroke Association"],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":736,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["10.1161\/STR.0b013e3181fcb238"],"URL":"https:\/\/doi.org\/10.1161\/str.0b013e3181fcb238","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2]]},"assertion":[{"value":"2010-12-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}