{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T22:34:33Z","timestamp":1758926073273},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            We hypothesized that direct cervical investigation with Power M-Mode Doppler (PMD) combined with single-gate Doppler spectral analysis (SGDSA) using a 2-MHz pulsed-wave Doppler transducer would show reasonable accuracy parameters when compared with standard color-coded carotid duplex ultrasound (CDU).\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            We prospectively screened for cervical internal carotid artery (ICA) stenosis by direct observation using a 2 MHz PMD\/SGDSA device. PMD identified the artery (location, depth, flow direction) and SGDSA assessed waveform; peak systolic, end diastolic, and mean flow velocities (MFV) of the common carotid artery; cervical ICA proximally and distally; and external carotid artery. Diagnostic accuracy was compared with concurrent carotid duplex ultrasound. The continuity principle was applied using the proximal\/distal cervical ICA MFV ratio.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            We examined 456 vessels (228 patients). Using ICA proximally\/ICA distally MFV ratio of 1.5 or greater or absence of ICA signature, for 40% to 59% or greater stenosis (including occlusions), sensitivity was 75.4%, specificity 99.8%, positive predictive value 97.7%, negative predictive value 96.6%, and accuracy 96.7%. For MFV ratio 1.6 or greater or absence of ICA signature and 60% to 79% or greater stenosis (including occlusions), sensitivity was 92.3%, specificity 98.1%, positive predictive value 81.8%, negative predictive value 99.3%, and accuracy 97.6%.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            Use of combined PMD and SGDSA to directly observe the extracranial ICA is reasonably accurate compared with carotid duplex ultrasound. Using the MFV ratio of proximal\/distal extracranial ICA improves accuracy parameters and provides a quick and effective bedside screen for ICA stenosis. This novel technique should be considered part of the standard PMD\/transcranial Doppler examination.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.106.480491","type":"journal-article","created":{"date-parts":[[2007,4,27]],"date-time":"2007-04-27T01:03:45Z","timestamp":1177635825000},"page":"1780-1785","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Power M-Mode Doppler and Single-Gate Spectral Analysis Using a 2-MHz Pulsed-Wave Doppler Transducer to Directly Detect Cervical Internal Carotid Artery Stenosis"],"prefix":"10.1161","volume":"38","author":[{"given":"Vasile N.","family":"Popa","sequence":"first","affiliation":[{"name":"From the Ochsner Stroke Team, Department of Neurology (V.N.P., C.L.L., R.A.F.), Ochsner Clinic Foundation, New Orleans, La; and Spencer Vascular Laboratories (M.P.S.), a Division of Spencer Technologies Inc., Seattle, Wash."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merrill P.","family":"Spencer","sequence":"additional","affiliation":[{"name":"From the Ochsner Stroke Team, Department of Neurology (V.N.P., C.L.L., R.A.F.), Ochsner Clinic Foundation, New Orleans, La; and Spencer Vascular Laboratories (M.P.S.), a Division of Spencer Technologies Inc., Seattle, Wash."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlene L.","family":"Lion","sequence":"additional","affiliation":[{"name":"From the Ochsner Stroke Team, Department of Neurology (V.N.P., C.L.L., R.A.F.), Ochsner Clinic Foundation, New Orleans, La; and Spencer Vascular Laboratories (M.P.S.), a Division of Spencer Technologies Inc., Seattle, Wash."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Felberg","sequence":"additional","affiliation":[{"name":"From the Ochsner Stroke Team, Department of Neurology (V.N.P., C.L.L., R.A.F.), Ochsner Clinic Foundation, New Orleans, La; and Spencer Vascular Laboratories (M.P.S.), a Division of Spencer Technologies Inc., Seattle, Wash."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108153250701"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520420037035"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.8.3.3289100"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(95)70060-9"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.30.2.402"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.28.1.133"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.31.1.140"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2001.tb00040.x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(01)00486-0"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.10.3.462521"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2002.tb00127.x"},{"key":"e_1_3_3_12_2","first-page":"195","volume":"16","year":"1995","unstructured":"Muller M, Hermes M, Bruckmann H, Schimrigk K. 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AJNR Am J Neuroradiol. 1995; 16: 195\u2013202.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/jon20001011"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.28.10.1966"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2006.00044.x"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.106.480491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:22:23Z","timestamp":1715602943000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.106.480491"}},"subtitle":["Use of the Continuity Principle: Report of a Novel Technique"],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1161\/STROKEAHA.106.480491"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.106.480491","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]},"assertion":[{"value":"2006-12-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-04-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}