{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:10:19Z","timestamp":1790957419061,"version":"4.1.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            Rapid and safe recanalization of occluded intracranial arteries in acute ischemic stroke (AIS) is challenging. Newly available self-expanding intracranial atherosclerotic stents (SEIS), which can be deployed rapidly and safely, make acute stenting an option for treating AIS. We present the feasibility of this technique.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            A retrospective analysis evaluated procedural protocols and clinical response to treatment in patients with AIS treated with SEIS. Descriptive statistics are presented with initial and follow-up National Institutes of Health Stroke Scale and modified Rankin Score.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Nine patients with AIS underwent acute SEIS placement. There was successful deployment of the Neuroform (n=4) and Wingspan (n=4\/5) stents in the M1\/M2 (n=5) and M3 (n=1) middle cerebral artery segments, intracranial internal carotid artery (one of 2), and intracranial vertebrobasilar junction (one). Mean time of SEIS deployment from AIS onset was 5.1 hours. Complete (Thrombolysis in Cerebral Ischemia\/Thrombolysis in Myocardial Ischemia 3) and partial\/complete (Thrombolysis in Cerebral Ischemia\/Thrombolysis in Myocardial Ischemia 2 or 3) recanalization occurred in 67% and 89%, respectively. One intracranial hemorrhage (11%) and one acute in-stent thrombosis (successfully treated with abciximab and balloon angioplasty) occurred. Stroke-related mortality occurred in 3 of 9 (33%) patients and survivors had modified Rankin Score \u22642. Follow-up angiography (mean, 8 months; range, 2 to 14 months) in 4 of 9 patients showed no stent restenosis.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            This preliminary experience with SEIS in refractory AIS demonstrated the technical feasibility and high rate of recanalization with acute stenting. Long-term safety and strategies to limit in-stent thrombosis and optimize periprocedural management are crucial before initiating future randomized efficacy studies with SEIS in AIS refractory to standard therapy.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.107.510966","type":"journal-article","created":{"date-parts":[[2008,6,13]],"date-time":"2008-06-13T02:23:39Z","timestamp":1213323819000},"page":"2392-2395","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":130,"title":["Interventional Acute Ischemic Stroke Therapy With Intracranial Self-Expanding Stent"],"prefix":"10.1161","volume":"39","author":[{"given":"Osama O.","family":"Zaidat","sequence":"first","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Wolfe","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed I.","family":"Hussain","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Lynch","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi","family":"Gupta","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Delap","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel T.","family":"Torbey","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian-Fred","family":"Fitzsimmons","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (O.O.Z., T.W., S.I.H., J.R.L., J.D., M.T.T., B.-F.S.), Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wis; and the Department of Neurology (R.G.), Michigan State University, East Lansing, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512143332401"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.107.483131"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.21.2003"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000121641.77121.98"},{"key":"e_1_3_2_5_2","first-page":"880","volume":"26","year":"2005","unstructured":"Zaidat OO, Suarez JI, Sunshine JL, Tarr RW, Alexander MJ, Smith TP, Enterline DS, Selman WR, Landis DM. Thrombolytic therapy of acute ischemic stroke: correlation of angiographic recanalization with clinical outcome. AJNR Am J Neuroradiol. 2005; 26: 880\u2013884.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000020363.23725.67"},{"key":"e_1_3_2_7_2","first-page":"251","volume":"50","year":"2002","unstructured":"Suarez JI, Zaidat OO, Sunshine JL, Tarr R, Selman WR, Landis DM. Endovascular administration after intravenous infusion of thrombolytic agents for the treatment of patients with acute ischemic strokes. Neurosurgery. 2002; 50: 251\u2013259;discussion 259\u2013260.","journal-title":"Neurosurgery"},{"key":"e_1_3_2_8_2","first-page":"1177","volume":"27","year":"2006","unstructured":"Smith WS. Safety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the Multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part I. AJNR Am J Neuroradiol. 2006; 27: 1177\u20131182.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_2_9_2","first-page":"322","volume":"25","year":"2004","unstructured":"Qureshi AI, Siddiqui AM, Kim SH, Hanel RA, Xavier AR, Kirmani JF, Suri MF, Boulos AS, Hopkins LN. Re-occlusion of recanalized arteries during intra-arterial thrombolysis for acute ischemic stroke. AJNR Am J Neuroradiol. 2004; 25: 322\u2013328.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000257963.65728.e8"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","unstructured":"Zaidat OO Klucznik R Alexander MJ Chaloupka J Lutsep H Barnwell S Mawad M Lane B Lynn MJ Chimowitz M. The NIH Multi-center Registry on the Wingspan Stent Use for Symptomatic 70\u201399% Intracranial Arterial Stenosis. Presented in the International Stroke Conference late breaking news session; February 2007.","DOI":"10.1212\/01.wnl.0000306308.08229.a3"},{"key":"e_1_3_2_12_2","first-page":"816","volume":"28","year":"2007","unstructured":"Levy EI, Mehta R, Gupta R, Hanel RA, Chamczuk AJ, Fiorella D, Woo HH, Albuquerque FC, Jovin TG, Horowitz MB, Hopkins LN. Self-expanding stents for recanalization of acute cerebrovascular occlusions. AJNR Am J Neuroradiol. 2007; 28: 816\u2013822.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_2_13_2","first-page":"382","volume":"28","year":"2007","unstructured":"Tomsick T. TIMI, TIBI, TICI: I came, I saw, I got confused. AJNR Am J Neuroradiol. 2007; 28: 382\u2013384.","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.107.510966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:41:14Z","timestamp":1715604074000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.107.510966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1161\/STROKEAHA.107.510966"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.107.510966","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"2007-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-01-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-06-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}