{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:01:59Z","timestamp":1778824919298,"version":"3.51.4"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            Stroke MRI protocols provide useful information about underlying vessel pathologies in the anterior circulation by means of intracranial time-of-flight angiography. However, these protocols mostly fail in the posterior circulation to differentiate between congenital variants and secondary thrombosis. Therefore, a high-resolution anatomic True Fast Imaging in Steady State Precession sequence, added to a commonly used stroke imaging protocol, was evaluated.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            MRIs of all emergency admissions to the stroke unit over 2 months were analyzed. Variations in the posterior circulation as displayed by time-of-flight and by the True Fast Imaging in Steady State Precession sequence, respectively, were graded by 2 readers blinded to the diagnosis.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            In the time-of-flight angiography, 50% of patients presented with distinctive vertebrobasilar alterations. Half of these were judged as high-grade anomalies, of which the True Fast Imaging in Steady State Precession sequence identified 25% as hypoplasia. In 40% of all patients with posterior ischemia, the True Fast Imaging in Steady State Precession sequence confirmed an acquired occlusion of the vertebrobasilar arteries.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            The addition of an anatomic (True Fast Imaging in Steady State Precession) to a functional sequence (time-of-flight) in stroke MRI protocols enables the differentiation between artery occlusions and hypoplastic variants of the vertebral arteries.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.107.512772","type":"journal-article","created":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T01:36:35Z","timestamp":1212716195000},"page":"2382-2384","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["MRI-Based Separation of Congenital and Acquired Vertebrobasilar Artery Anomalies in Ischemic Stroke of the Posterior Circulation"],"prefix":"10.1161","volume":"39","author":[{"given":"Wolfgang","family":"Freund","sequence":"first","affiliation":[{"name":"From the Department of Diagnostic and Interventional Radiology (W.F., A.J.A.), University Hospitals, Ulm, Germany; and the Department of Neurology (J.K., R.H.), University of Ulm, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Kassubek","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic and Interventional Radiology (W.F., A.J.A.), University Hospitals, Ulm, Germany; and the Department of Neurology (J.K., R.H.), University of Ulm, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrik J.","family":"Aschoff","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic and Interventional Radiology (W.F., A.J.A.), University Hospitals, Ulm, Germany; and the Department of Neurology (J.K., R.H.), University of Ulm, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Huber","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic and Interventional Radiology (W.F., A.J.A.), University Hospitals, Ulm, Germany; and the Department of Neurology (J.K., R.H.), University of Ulm, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-003-1846-3"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/02841850510016009"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540290081021"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000195171.29940.79"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.107.512772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:41:04Z","timestamp":1715604064000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.107.512772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":4,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1161\/STROKEAHA.107.512772"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.107.512772","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"2007-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-06-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}