{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:35:35Z","timestamp":1791434135509,"version":"4.3.3"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            Suboccipital decompressive craniectomy (SDC) is a life-saving intervention for patients with malignant cerebellar infarction. However, long-term outcome has not been systematically analyzed.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            In this monocentric retrospective study we analyzed mortality, long-term functional outcome, and quality of life of all consecutive patients that were treated by SDC for malignant cerebellar infarction in our institution between 1995 and 2006.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            A total of 57 patients were identified. All of them were treated by bilateral SDC. An external ventricular drainage was inserted in 82%, necrotic tissue was evacuated in 56% of patients. There were no fatal procedural complications. Five patients were lost for follow-up. In the remaining 52 patients, the mean follow-up interval was 4.7 years (1 to 11 years). Within the first 6 months after surgery 16 of 57 patients (28%) had died. At follow-up, 21 of 52 patients (40%) had died and 4 patients (8%) lived with major disability (mRS 4 or 5). Twenty-one patients (40%) lived functionally independent (mRS 0 to 2). The presence of additional brain stem infarction was associated with poor outcome (mRS \u22654; hazard ratio: 9.1;\n            <jats:italic>P<\/jats:italic>\n            =0.001). Quality of life in survivors was moderately lower than in healthy controls.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            SDC is a safe procedure in patients with malignant cerebellar infarction. Infarct- but not procedure-related early mortality is substantial. Long-term outcome in survivors is acceptable, particularly in the absence of brain stem infarction.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.109.550871","type":"journal-article","created":{"date-parts":[[2009,7,3]],"date-time":"2009-07-03T02:43:22Z","timestamp":1246589002000},"page":"3045-3050","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":102,"title":["Long-Term Outcome After Suboccipital Decompressive Craniectomy for Malignant Cerebellar Infarction"],"prefix":"10.1161","volume":"40","author":[{"given":"Thomas","family":"Pfefferkorn","sequence":"first","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Eppinger","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Linn","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Birnbaum","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju\u0308rgen","family":"Herzog","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Straube","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Dichgans","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; and Neurologische Klinik (J.H.), Bad Aibling, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Grau","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (T.P., U.E., T.B., A.S., M.D.), Neuroradiology (J.L.), and Neurosurgery (S.G.), Klinikum Grosshadern, University of Munich, Germany; 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J Neurol Neurosurg Psychiatry. 2004; 75: 270\u2013274.","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.109.550871","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:43:30Z","timestamp":1715604210000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.109.550871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":29,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1161\/STROKEAHA.109.550871"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.109.550871","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9]]},"assertion":[{"value":"2009-02-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-05-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}