{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:20:03Z","timestamp":1791624003344,"version":"4.3.4"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            Positive effects of moxibustion for stroke rehabilitation may be seen in real clinical practice. Currently, no systematic reviews are available. The aim of this systematic review was to analyze the trial data on the effectiveness of moxibustion for stroke rehabilitation.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            Fourteen databases were searched without language restriction. Randomized clinical trials were included if moxibustion was tested as the sole treatment or as an adjunct to other treatments for stroke rehabilitation.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Nine randomized clinical trials met our inclusion criteria. Three randomized clinical trials reported favorable effects of moxibustion plus standard care on motor function versus standard care alone (N=142; standardized mean difference=0.72; 95% confidence interval, 0.37 to 1.08;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.0001). Three randomized clinical trials compared the effects of moxibustion on activities of daily living alone but failed to show favorable effects of moxibustion.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusion\u2014<\/jats:italic>\n            <\/jats:bold>\n            This systematic review found limited effectiveness of moxibustion as an adjunct to standard care in stroke rehabilitation.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.109.566851","type":"journal-article","created":{"date-parts":[[2010,2,12]],"date-time":"2010-02-12T03:54:08Z","timestamp":1265946848000},"page":"817-820","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":44,"title":["Moxibustion for Stroke Rehabilitation"],"prefix":"10.1161","volume":"41","author":[{"given":"Myeong Soo","family":"Lee","sequence":"first","affiliation":[{"name":"From the Korea Institute of Oriental Medicine (M.S.L., J.-I.K.), Daejeon, South Korea; Peninsula Medical School (M.S.L., E.E.), Universities of Exeter and Plymouth, Exeter, England; Pusan National University (B.-C.S.), Yangsan, South Korea; and Dongguk University (C.-h.H.), Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Cheul","family":"Shin","sequence":"additional","affiliation":[{"name":"From the Korea Institute of Oriental Medicine (M.S.L., J.-I.K.), Daejeon, South Korea; Peninsula Medical School (M.S.L., E.E.), Universities of Exeter and Plymouth, Exeter, England; Pusan National University (B.-C.S.), Yangsan, South Korea; and Dongguk University (C.-h.H.), Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-In","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Korea Institute of Oriental Medicine (M.S.L., J.-I.K.), Daejeon, South Korea; Peninsula Medical School (M.S.L., E.E.), Universities of Exeter and Plymouth, Exeter, England; Pusan National University (B.-C.S.), Yangsan, South Korea; and Dongguk University (C.-h.H.), Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-ho","family":"Han","sequence":"additional","affiliation":[{"name":"From the Korea Institute of Oriental Medicine (M.S.L., J.-I.K.), Daejeon, South Korea; Peninsula Medical School (M.S.L., E.E.), Universities of Exeter and Plymouth, Exeter, England; Pusan National University (B.-C.S.), Yangsan, South Korea; and Dongguk University (C.-h.H.), Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edzard","family":"Ernst","sequence":"additional","affiliation":[{"name":"From the Korea Institute of Oriental Medicine (M.S.L., J.-I.K.), Daejeon, South Korea; Peninsula Medical School (M.S.L., E.E.), Universities of Exeter and Plymouth, Exeter, England; Pusan National University (B.-C.S.), Yangsan, South Korea; and Dongguk University (C.-h.H.), Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2008.04.014"},{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Higgins JPT Douglas GA. Assessing risk of bias in included studies. In: Julian PTH Green S eds. Cochrane Handbook for Systematic Reviews of Interventions. West Sussex England: Wiley-Blackwell; 2008: 187\u2013241.","DOI":"10.1002\/9780470712184.ch8"},{"key":"e_1_3_2_3_2","first-page":"278","volume":"29","year":"2008","unstructured":"Lee S, Kim J, Son Y, Jeong H, Kim J, Kwon J, Kim Y. A clinical study of moxibustion therapy\u2019s effect on functional recovery in hemiplegia on stroke [in Korean]. Korean J Orient Int Med. 2008; 29: 278\u2013284.","journal-title":"Korean J Orient Int Med"},{"key":"e_1_3_2_4_2","first-page":"283","volume":"24","year":"2003","unstructured":"Choi Y, Kim T, Jung WS, Moon S. Effects of moxibustion on the hemiplegic upper extremity after stroke [in Korean]. Korean J Orient Int Med. 2003; 24: 283\u2013289.","journal-title":"Korean J Orient Int Med"},{"key":"e_1_3_2_5_2","first-page":"93","year":"2003","unstructured":"Choi Y, Kim J, Jung S, Lee K. Effects of moxibustion on the edematous hand in hemiplegic patients [in Korean]. Korean J Orient Int Med. 2003; (suppl 1): 93\u2013103.","journal-title":"Korean J Orient Int Med"},{"key":"e_1_3_2_6_2","first-page":"1391","volume":"35","year":"2008","unstructured":"Chen HP, Guo M, Huang J, Tang W, Lv YL. Moxibustion and Bobath therapy: ankle joints function rehabilitation during the early stage after stroke [in Chinese]. Liaoning J Tradit Chin Med. 2008; 35: 1391\u20131393.","journal-title":"Liaoning J Tradit Chin Med"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X03001077"},{"key":"e_1_3_2_8_2","first-page":"78","volume":"40","year":"2008","unstructured":"Xiao H, Bao QH, Wang L. Clinical observation moxibustion on temperature-sensitive to reduce the thermal stroke patients after catheter inserted [in Chinese]. J New Chin Med. 2008; 40: 78\u201379.","journal-title":"J New Chin Med"},{"key":"e_1_3_2_9_2","first-page":"621","volume":"26","year":"2006","unstructured":"Liu HL, Wang LP. Randomized controlled study on ginger-salt-partitioned moxibustion at shenque (cv 8) on urination disorders poststroke [in Chinese]. Zhongguo Zhen Jiu. 2006; 26: 621\u2013624.","journal-title":"Zhongguo Zhen Jiu"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X07005417"},{"key":"e_1_3_2_11_2","first-page":"3.","volume":"2006","year":"2006","unstructured":"Chen W, Tan M, Liang LA, Weng TL. Effect of moxibustion at zusanli (st36) and xuanzhong (gb39) on cerebrovascular function in the patient of ischemic apoplexy [in Chinese]. Chin Acupunct Moxibustion. 2006; 2006: 3.","journal-title":"Chin Acupunct Moxibustion"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.41806"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520290060030"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.109.566851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:04:52Z","timestamp":1715609092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.109.566851"}},"subtitle":["Systematic Review"],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1161\/STROKEAHA.109.566851"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.109.566851","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]},"assertion":[{"value":"2009-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-12-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-02-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}