{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:53:11Z","timestamp":1791219191475,"version":"4.1.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            The purpose of this study is to report our preliminary experience with the flow-diverter Silk stent for the endovascular treatment of intracranial aneurysms.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            This prospective study was approved by the authors\u2019 ethical committees. Twenty-nine patients with 34 fusiform or wide-necked unruptured aneurysms were included and treated by Silk stent placement alone by 2 physicians in 3 different centers. Technical issues, immediate findings, delayed complications, clinical follow-up, and imaging follow-up at 3 and 6 months were assessed.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Endovascular treatment was successfully performed in 26 patients (90%). In 3 patients, the stent could not be delivered. Mortality and morbidity rates were of 4% (1 of 26) and 15% (4 of 26), respectively; 1 patient died from a delayed aneurysm rupture related to stent migration, 3 experienced a thromboembolic event, and 1 patient developed progressive visual disturbances related to an increased mass effect. Clinical outcome in 25 patients was unchanged (n=19), improved (n=2), or worsened (=4). Angiographic follow-up in 24 patients (29 aneurysms) showed 20 complete occlusions (69%), 1 neck remnant (3.5%), and 8 incomplete occlusions (27.5%). Significant parent artery stenosis at 6 months occurred in 8 cases (33%).\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            Despite the potential interest of the Silk flow-diverter stent to treat complex intracranial aneurysms without coils, the delayed complication rate is quite high and leads to use this technique only in selective cases.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.110.589911","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T02:47:49Z","timestamp":1282877269000},"page":"2247-2253","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":281,"title":["Flow-Diverter Stent for the Endovascular Treatment of Intracranial Aneurysms"],"prefix":"10.1161","volume":"41","author":[{"given":"Boris","family":"Lubicz","sequence":"first","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Collignon","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gai\u0308","family":"Raphaeli","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Pruvo","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michae\u0308l","family":"Bruneau","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"De Witte","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Leclerc","sequence":"additional","affiliation":[{"name":"From the Departments of Neuroradiology (B.L., G.R.) and Neurosurgery (M.B., O.D.), Erasme University Hospital, Brussels, Belgium; the Department of Radiology (L.C.), CHR Citadelle, Lie\u0300ge, Belgium; and the Department of Neuroradiology (X.L., J.P.P.), Roger Salengro University Hospital, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-009-0519-6"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.558114"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000325873.44881.6e"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000339109.98070.65"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","unstructured":"Szikora I Berentei Z Kulcsar Z Marosfoi M Vajda ZS Lee W Berez A Nelson PK. Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the Pipeline embolization device. AJNR Am J Neuroradiol. 2010 Feb 11 [Epub ahead of print].","DOI":"10.3174\/ajnr.A2023"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.533760"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.524124"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000365370.82554.08"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","unstructured":"Turowski B Macht S Kulcs\u00e1r Z H\u00e4nggi D Stummer W. Early fatal hemorrhage after endovascular cerebral aneurysm treatment with a flow diverter (SILK-Stent): do we need to rethink our concepts? Neuroradiology. 2010 Mar 26 [Epub ahead of print].","DOI":"10.1007\/s00234-010-0676-7"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.19.12.3201508"},{"key":"e_1_3_2_11_2","unstructured":"Chapot R. Experience with Silk stent in 25 aneurysms. Presented at World Federation of Interventional and Therapeutic Neuroradiology meeting June 29 to July 3 Montreal Canada."}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.110.589911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:39:30Z","timestamp":1715611170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.110.589911"}},"subtitle":["A Prospective Study in 29 Patients With 34 Aneurysms"],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1161\/STROKEAHA.110.589911"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.110.589911","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"2010-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-06-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-08-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}