{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:24:15Z","timestamp":1791123855222,"version":"4.1.0"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background and Purpose\u2014<\/jats:italic>\n            <\/jats:bold>\n            The purpose of this study was to demonstrate a new approach to the use of a self-expanding stent in the treatment of acute ischemic stroke.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods\u2014<\/jats:italic>\n            <\/jats:bold>\n            Twenty-two consecutive patients with acute intracerebral artery occlusions were treated with a self-expandable intracranial stent, which was withdrawn in its unfolded state. For this technique, we used the Solitaire AB\/FR, which is the only intracranial stent that is fully recoverable. Eight patients had an occlusion of the basilar artery, 12 had a middle cerebral artery occlusion, and 2 had terminal carotid artery occlusions; 6 of these had to be treated first for an acute occlusion originating in the internal carotid artery. Recanalization results were assessed by follow-up angiography immediately after the procedure. Neurologic status was evaluated before and after treatment (90-day follow-up) according to the National Institutes of Health Stroke Scale and modified Rankin scale.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Successful revascularization was achieved in 20 of 22 (90.9%) patients (thrombolysis in cerebral infarction [TICI] 2a\/b and 3), a TICI 3 state was accomplished in 12 patients, and partial recanalization or slow distal branch filling with filling of more than two-thirds of the vessel territory was achieved in 8 patients (TICI 2b). There was immediate flow restoration in 21 of 22 (95.4%) cases after deployment of the device. The stent was removed in its unfolded state in all patients. The mean time from stroke symptom onset to recanalization was 277 minutes, with a standard deviation of 118 minutes. Mean National Institutes of Health Stroke Scale score on admission was 19.4, with a standard deviation of 5.7. Almost two-thirds of the patients (63.6%) improved by &gt;10 points on the National Institutes of Health Stroke Scale at discharge, and 50% showed a modified Rankin scale score of \u22642 at 90 days (59% with a modified Rankin scale \u22643). Mortality was 18.1%. In 1 case, an asymptomatic intracranial hemorrhage was detected on control computed tomography, and 2 patients had a symptomatic intracranial hemorrhage.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusion\u2014<\/jats:italic>\n            <\/jats:bold>\n            Withdrawal of an unfolded, fully recoverable, intracranial stent yielded very promising angiographic and clinical results. It combines the advantages of prompt flow restoration and mechanical thrombectomy.\n          <\/jats:p>","DOI":"10.1161\/strokeaha.110.592071","type":"journal-article","created":{"date-parts":[[2010,10,15]],"date-time":"2010-10-15T02:56:24Z","timestamp":1287111384000},"page":"2559-2567","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":207,"title":["Stent-Assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusions"],"prefix":"10.1161","volume":"41","author":[{"given":"C.","family":"Roth","sequence":"first","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Papanagiotou","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Behnke","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Walter","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Haass","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Becker","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland University Hospital, Homburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Fassbender","sequence":"additional","affiliation":[{"name":"From the Departments of Diagnostic and Interventional Neuroradiology (C.R., P.P., M.P., H.K., M.-S.R., W.R.) and of Neurology (S.B., S.W., A.H., C.B., K.F.), Saarland 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