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Early detection of ICAD may allow therapeutic intervention while the disease is still asymptomatic. The Barcelon\u00e8s Nord and Maresme Asymptomatic Intracranial Atherosclerosis Study is presented here. The main prognostic factors that characterize the patients who are at a higher risk for ICAD recurrence are classified and discussed. The best treatment for ICAD remains to be established. The Stenting Versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Study is currently ongoing to address this crucial issue. These and other topics will be discussed at the Fifth International Intracranial Atherosclerosis Conference (Valladolid, Spain, autumn 2011).<\/jats:p>","DOI":"10.1161\/strokeaha.110.597278","type":"journal-article","created":{"date-parts":[[2010,12,17]],"date-time":"2010-12-17T04:16:58Z","timestamp":1292559418000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":187,"title":["Intracranial Atherosclerosis"],"prefix":"10.1161","volume":"42","author":[{"given":"Juan F.","family":"Arenillas","sequence":"first","affiliation":[{"name":"From the Stroke Unit, Department of Neurology, Hospital Cl\u00ednico Universitario, Valladolid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.3.812"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2006.2.4.225"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.1.14"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.505776"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000132637.30287.B4"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.496513"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000111525"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00278.x"},{"key":"e_1_3_3_10_2","article-title":"Intraplaque hemorrhage in symptomatic intracranial atherosclerotic disease","author":"Turan TN","unstructured":"Turan TN, Bonilha L, Morgan PS, Adams RJ, Chimowitz MI. 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