{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:47:22Z","timestamp":1782935242615,"version":"3.54.5"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Purpose\u2014<\/jats:title>\n                    <jats:p>Coffee consumption has been inconsistently associated with stroke incidence and mortality in previous studies. We investigated the association between coffee consumption and stroke incidence in the Swedish Mammography Cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\u2014<\/jats:title>\n                    <jats:p>We prospectively followed of 34 670 women without a history of cardiovascular disease or cancer at baseline in 1997. Coffee consumption was assessed in 1997 using a self-administered questionnaire. Incident stroke cases were ascertained from the Swedish Hospital Discharge Registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results\u2014<\/jats:title>\n                    <jats:p>\n                      During a mean follow-up of 10.4 years, we ascertained 1680 stroke events, including 1310 cerebral infarctions, 154 intracerebral hemorrhages, 79 subarachnoid hemorrhages, and 137 unspecified strokes. After adjustment for other risk factors, coffee consumption was associated with a statistically significant lower risk of total stroke, cerebral infarction, and subarachnoid hemorrhage but not intracerebral hemorrhage. The multivariable relative risks of total stroke across categories of coffee consumption (&lt;1 cup\/day, 1 to 2 cups\/day, 3 to 4 cups\/day, and \u22655 cups\/day) were 1.00, 0.78 (95% CI, 0.66 to 0.91), 0.75 (95% CI, 0.64 to 0.88), and 0.77 (95% CI, 0.63 to 0.92, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      for trend=0.02). The association between coffee consumption and cerebral infarction was not modified by smoking status, body mass index, history of diabetes or hypertension, or alcohol consumption.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>These findings suggest that low or no coffee consumption is associated with an increased risk of stroke in women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.110.603787","type":"journal-article","created":{"date-parts":[[2011,3,10]],"date-time":"2011-03-10T23:18:04Z","timestamp":1299799084000},"page":"908-912","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":84,"title":["Coffee Consumption and Risk of Stroke in Women"],"prefix":"10.1161","volume":"42","author":[{"given":"Susanna C.","family":"Larsson","sequence":"first","affiliation":[{"name":"From the Division of Nutritional Epidemiology (S.C.L., A.W.), National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; and the Department of Chronic Disease Prevention (J.V.), National Institute for Health and Welfare, Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarmo","family":"Virtamo","sequence":"additional","affiliation":[{"name":"From the Division of Nutritional Epidemiology (S.C.L., A.W.), National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; and the Department of Chronic Disease Prevention (J.V.), National Institute for Health and Welfare, Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Wolk","sequence":"additional","affiliation":[{"name":"From the Division of Nutritional Epidemiology (S.C.L., A.W.), National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; and the Department of Chronic Disease Prevention (J.V.), National Institute for Health and Welfare, Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.1.97"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.06.051"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.10.1199-b"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28548"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.4.888"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf0710985"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.826164"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.504183"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00023-7"},{"key":"e_1_3_3_11_2","first-page":"1","article-title":"Total fluid and specific beverage intake and mortality due to IHD and stroke in The Netherlands cohort study","author":"Leurs LJ","year":"2010","unstructured":"Leurs LJ, Schouten LJ, Goldbohm RA, van den Brandt PA. Total fluid and specific beverage intake and mortality due to IHD and stroke in The Netherlands cohort study. Br J Nutr. 2010:1\u201310.","journal-title":"Br J Nutr"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.109.109314"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-006-0435-9"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-009-1311-1"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2009.097311"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.1.41"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801597"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2008.286"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2010.161"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.110.603787","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:37:38Z","timestamp":1715596658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.110.603787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1161\/STROKEAHA.110.603787"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.110.603787","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.11634956.12815070","asserted-by":"object"}]},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"2010-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-03-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}