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In fact, most patients who undergo LACA have a rather low annual stroke risk even when left untreated, whereas LACA imposes a risk of procedure-related stroke of \u22480.5% to 1%. In addition, LACA may cause cerebral microemboli, resulting in ischemic lesions. These cerebral lesions, detectable by high-resolution MRI, could contribute to neuropsychological deficits and cognitive dysfunction. Furthermore, recurrent atrial fibrillaton episodes can be detected up to years after LACA and might cause ischemic strokes, especially in those patients in whom therapeutic anticoagulation was discontinued. Further prospective multicenter trials are needed to identify procedure-dependent risk factors for stroke and to optimize postprocedural anticoagulation management.<\/jats:p>","DOI":"10.1161\/strokeaha.111.627067","type":"journal-article","created":{"date-parts":[[2011,12,9]],"date-time":"2011-12-09T07:29:06Z","timestamp":1323415746000},"page":"265-270","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":69,"title":["Left Atrial Catheter Ablation and Ischemic Stroke"],"prefix":"10.1161","volume":"43","author":[{"given":"Karl Georg","family":"Haeusler","sequence":"first","affiliation":[{"name":"From the Department of Neurology (K.G.H., M.E.), Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Germany; Center for Stroke Research Berlin (K.G.H., M.E.), Berlin, Germany; Department of Cardiology and Angiology (P.K.), University Hospital M\u00fcnster, M\u00fcnster, Germany; and University of Birmingham Center for Cardiovascular Sciences (P.K.), Birmingham, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulus","family":"Kirchhof","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (K.G.H., M.E.), Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Germany; Center for Stroke Research Berlin (K.G.H., M.E.), Berlin, Germany; Department of Cardiology and Angiology (P.K.), University Hospital M\u00fcnster, M\u00fcnster, Germany; and University of Birmingham Center for Cardiovascular Sciences (P.K.), Birmingham, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Endres","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (K.G.H., M.E.), Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Germany; Center for Stroke Research Berlin (K.G.H., M.E.), Berlin, Germany; Department of Cardiology and Angiology (P.K.), University Hospital M\u00fcnster, M\u00fcnster, Germany; and University of Birmingham Center for Cardiovascular Sciences (P.K.), Birmingham, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq278"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.8.983"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn599"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn341"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.12.004"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(02)01253-6"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0803778"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp235"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-7-72"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31820f14c0"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.hrthm.2007.04.005","article-title":"HRS\/EHRA\/ECAS expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. 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