{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:11:04Z","timestamp":1783473064046,"version":"3.55.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>We assessed whether echocardiography can predict paroxysmal atrial fibrillation (PAF) in patients with cerebral ischemia presenting in sinus rhythm.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>Within the prospective Find-AF cohort, 193 consecutive patients with cerebral ischemia and sinus rhythm on presentation had evaluation of echocardiographic parameters of left atrial size and function. PAF was diagnosed by 7-day Holter monitoring.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              In 26 patients with PAF, late diastolic Doppler (A) and tissue Doppler (a\u2032) velocities were lower whereas left atrial diameter, left atrial volume index (LAVI), LAVI\/A, and LAVI\/a\u2032 were larger (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05 for all) than they were in 167 patients without PAF. In multivariate models A, a\u2032, LAVI\/A, and LAVI\/a\u2032 predicted the presence of PAF. Area under the receiver operating characteristic curve to diagnose PAF was highest for LAVI\/a\u2032 (0.813 [0.738; 0.889]). A previously suggested cut-off of LAVI\/a\u2032 &lt;2.3 had 92% sensitivity, 55.8% specificity, and 98% negative predictive value for PAF.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>LAVI\/a\u2032 &lt;2.3 can effectively rule out PAF in patients with cerebral ischemia.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.111.632836","type":"journal-article","created":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T04:53:47Z","timestamp":1318568027000},"page":"3643-3645","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":69,"title":["Transthoracic Echocardiography to Rule Out Paroxysmal Atrial Fibrillation as a Cause of Stroke or Transient Ischemic Attack"],"prefix":"10.1161","volume":"42","author":[{"given":"Raoul","family":"Stahrenberg","sequence":"first","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Edelmann","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Haase","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosine","family":"Lahno","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Seegers","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Weber-Kr\u00fcger","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meinhard","family":"Mende","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janin","family":"Wohlfahrt","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel","family":"Kermer","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Vollmann","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Hasenfu\u00df","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Gr\u00f6schel","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Wachter","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology and Pneumology (R.S., F.E., B.H., R.L., J.S., M.W.-K., D.V., G.H., R.W.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (J.W., P.K.), University of G\u00f6ttingen, G\u00f6ttingen, Germany; Department of Neurology (K.G.), University Medicine Mainz, Mainz, Germany; Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.8.983"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.021642"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.591958"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.137760"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90771-X"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.09.094"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.111.632836","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:14:14Z","timestamp":1715609654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.111.632836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1161\/STROKEAHA.111.632836"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.111.632836","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"2011-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-07-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}