{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:47:00Z","timestamp":1791002820140,"version":"4.1.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>The purpose of this study was to evaluate the mortality rates associated with cerebral venous\u2013sinus thrombosis in a large national sample.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>A cohort of patients with cerebral venous\u2013sinus thrombosis was identified from the National Inpatient Sample database for the years 2000 to 2007. According to the International Classification of Diseases, 9th Revision, Clinical Modification codes, cerebral venous\u2013sinus thrombosis is categorized into pyogenic and nonpyogenic groups. Multivariate logistic regression analysis was used to assess covariates associated with hospital mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>Among 3488 patients, the overall mortality rate was 4.39%, which was nonsignificantly higher among the pyogenic group (4.55% versus 3.52%; OR, 0.76; 95% CI, 0.47\u20131.23). In the pyogenic cerebral venous\u2013sinus thrombosis group, hematologic disorders were the most frequent predisposing condition (16.2%); whereas systemic malignancy followed by hematologic disorders were most common in the nonpyogenic group (14.08% and 10.04%, respectively). Predictors of mortality included age, intracerebral hemorrhage as well as the predisposing conditions of hematologic disorders, systemic malignancy, and central nervous system infection.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Compared with arterial stroke, CVST harbors a relatively low mortality rate. Death is determined by age, the presence of intracerebral hemorrhage, and certain predisposing conditions.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.111.635664","type":"journal-article","created":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T04:53:47Z","timestamp":1318568027000},"page":"262-264","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":105,"title":["Mortality of Cerebral Venous\u2013Sinus Thrombosis in a Large National Sample"],"prefix":"10.1161","volume":"43","author":[{"given":"Afshin Borhani","family":"Haghighi","sequence":"first","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall C.","family":"Edgell","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Cruz-Flores","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Feen","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paisith","family":"Piriyawat","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirav","family":"Vora","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Charles","family":"Callison","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Alshekhlee","sequence":"additional","affiliation":[{"name":"From the Souers Stroke Institute, Department of Neurology, St Louis University, St Louis, MO."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000047635"},{"key":"e_1_3_2_3_2","first-page":"101","article-title":"Cavernous sinus thrombophlebitis caused by sphenoid sinusitis\u2014report of autopsy case","volume":"20","author":"Soga Y","year":"2001","unstructured":"Soga Y, Oka K, Sato M, Kabata T, Kawasaki T, Kawano H, et al.. Cavernous sinus thrombophlebitis caused by sphenoid sinusitis\u2014report of autopsy case. Clin Neuropathol. 2001;20:101\u2013105.","journal-title":"Clin Neuropathol"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000117571.76197.26"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-004-0363-8"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000233887.17638.d0"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.6324"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000067117"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.111.635664","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:06:58Z","timestamp":1715609218000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.111.635664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1161\/STROKEAHA.111.635664"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.111.635664","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"2011-08-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-08-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}