{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:47:27Z","timestamp":1785199647177,"version":"3.55.0"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (\n              <jats:italic>P<\/jats:italic>\n              =0.004), and a poor functional outcome (modified Rankin Scale score &gt;2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55\u20134.07). An increase in burden count of NRCA was also associated with poor outcomes.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.113.001111","type":"journal-article","created":{"date-parts":[[2013,5,17]],"date-time":"2013-05-17T04:56:21Z","timestamp":1368766581000},"page":"2013-2015","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Nonrelevant Cerebral Atherosclerosis is a Strong Prognostic Factor in Acute Cerebral Infarction"],"prefix":"10.1161","volume":"44","author":[{"given":"Jinkwon","family":"Kim","sequence":"first","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Jin","family":"Song","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongbeom","family":"Song","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Sun","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Mo","family":"Nam","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Suk","family":"Nam","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Dae","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hoe","family":"Heo","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea (J.K.); and Departments of Neurology (T.-J.S., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000057847"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000319574"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.11.2641"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.112.661702"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.113.001111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T14:50:44Z","timestamp":1738075844000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.113.001111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1161\/STROKEAHA.113.001111"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.113.001111","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"2013-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-05-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}