{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:11:33Z","timestamp":1790237493309,"version":"4.1.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Cognitive changes after ischemic stroke are often overlooked, particularly acutely and in patients with mild or transient deficits. We assessed patients with transient ischemic attack (TIA)\/minor stroke with serial cognitive screening tests. We tested the hypothesis that mild acute deficits are transient and improve after TIA\/minor stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>Patients with acute TIA\/minor ischemic stroke, without a history of cognitive impairment, presenting with a National Institute of Health Stroke Scale score \u22643 were assessed &lt;72 hours of onset. Patients were administered the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) at days 1, 7, 30, and 90. Cognitive impairment was defined as MoCA &lt;26 and MMSE \u226426.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              One hundred patients with a median (interquartile range) National Institute of Health Stroke Scale score of 1 (2) and median age of 68 (20) years were included. Baseline median MoCA score (26 [4]) was lower than the MMSE (29 [2];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001). Cognitive impairment was detected in 54 of 100 patients (54%) with MoCA and 16 of 100 (16%;\n              <jats:italic>P<\/jats:italic>\n              =0.001) with MMSE. MoCA scores improved at day 7 (27 [5]), day 30 (28 [2]), and day 90 (28 [2];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001). Resolution of cognitive deficits was because of resolution of recall deficits.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Acute temporary cognitive impairment after TIA\/minor stroke is common. The MoCA is sensitive to these changes, but the MMSE is not. Routine cognitive assessment after TIA\/minor stroke may be warranted and relevant to return to activities even when other neurological deficits are not evident.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.114.004726","type":"journal-article","created":{"date-parts":[[2014,4,23]],"date-time":"2014-04-23T07:18:30Z","timestamp":1398237510000},"page":"1709-1715","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":75,"title":["Serial Montreal Cognitive Assessments Demonstrate Reversible Cognitive Impairment in Patients With Acute Transient Ischemic Attack and Minor Stroke"],"prefix":"10.1161","volume":"45","author":[{"given":"Leka","family":"Sivakumar","sequence":"first","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahesh","family":"Kate","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jeerakathil","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Camicioli","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Buck","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Butcher","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000333412"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2009.09.010"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-013-0418-4"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afs116"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-2-72"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1983.01790060110016"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.110.579888"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.111.633586"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.08.051"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.110.606277"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acn.2005.04.001"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.113.10.e409"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93206-O"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.1.35"},{"key":"e_1_3_3_17_2","volume-title":"TrainingCampus Network","author":"NIH Stroke Scale-English Program","year":"1999","unstructured":"NIH Stroke Scale-English Program. TrainingCampus Network. http:\/\/nihss-english.trainingcampus.net\/uas\/modules\/trees\/windex.aspx?resx=123. 1999. Accessed September 10, 2011."},{"key":"e_1_3_3_18_2","volume-title":"TrainingCampus Network","author":"Modified Rankin Scale-English Program","year":"1999","unstructured":"Modified Rankin Scale-English Program. TrainingCampus Network. http:\/\/rankin-english.trainingcampus.net\/uas\/modules\/trees\/windex.aspx. 1999. Accessed September 10, 2011."},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(82)90033-4"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000338905"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.114.004726","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:10:07Z","timestamp":1715609407000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.114.004726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1161\/STROKEAHA.114.004726"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.114.004726","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"2014-01-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-04-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}