{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:22:20Z","timestamp":1792041740831,"version":"4.4.0"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Patients with stroke are at risk for developing cognitive impairment. We tested whether the assessment of balance and gait can enhance the prediction of long-term cognitive outcome in stroke survivors.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>Participants were patients with first-ever, mild-moderate ischemic stroke or transient ischemic attack from the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study, a large prospective cohort study, who underwent 3-T MRI and were followed for \u22652 years using neurological, neuropsychological, and mobility examinations 6, 12, and 24 months after the index event.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              Data were available for 298 patients (age: 66.7\u00b19.6 years). Forty-six participants (15.4%) developed cognitive decline (CD) over the 2 years of follow-up. The CD group and cognitively intact group did not differ in their neurological deficits or in their infarct volume or location. Nonetheless, 6 months after stroke, the Timed Up and Go test took longer in those who later developed CD (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). Additionally, the CD group also had lower Berg Balance Scale scores (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), slower gait (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), and fewer correct answers during dual-task walking (\n              <jats:italic>P<\/jats:italic>\n              =0.006). Separate analyses of the patients with transient ischemic attack revealed similar results. Multivariate regression analysis showed that Timed Up and Go times &gt;12 s at 6 months after stroke\/transient ischemic attack was a significant independent risk marker of CD 24 months after stroke (odds ratio=6.07, 95% confidence interval: 1.36\u201327.15).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>These results suggest that measures of balance and gait are significant risk markers of cognitive status 2 years after stroke. Relatively simple, performance-based tests of mobility may enhance the identification of stroke\/transient ischemic attack survivors who have an increased risk of developing CD.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Clinical Trial Registration\u2014<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.clinicaltrials.gov\">http:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              . Unique identifier: NCT01926691.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.114.007346","type":"journal-article","created":{"date-parts":[[2015,2,13]],"date-time":"2015-02-13T04:16:50Z","timestamp":1423801010000},"page":"1077-1083","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Gait Measures as Predictors of Poststroke Cognitive Function"],"prefix":"10.1161","volume":"46","author":[{"given":"Einor","family":"Ben Assayag","sequence":"first","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shani","family":"Shenhar-Tsarfaty","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amos D.","family":"Korczyn","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efrat","family":"Kliper","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hen","family":"Hallevi","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludmila","family":"Shopin","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eitan","family":"Auriel","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Giladi","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Mike","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Halevy","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aner","family":"Weiss","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Mirelman","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natan M.","family":"Bornstein","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. Mirelman, N.M.B.); and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (E.B.A., A.D.K., E.K., H.H., E.A., N.G., N.M.B., J.M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Hausdorff","sequence":"additional","affiliation":[{"name":"From the Stroke Unit and the Center for the Study of Movement, Cognition and Mobility, Department of Neurology, Tel Aviv Medical Center, Tel Aviv, Israel (E.B.A., S.-S.T., E.K., H.H., L.S., E.A., N.G., A. Mike, A.H., A.W., A. 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