{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:26:16Z","timestamp":1791271576882,"version":"4.1.0"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Contrary to usual static vascular imaging techniques, contrast-enhanced dynamic magnetic resonance angiography (dMRA) enables dynamic study of cerebral vessels. We evaluated dMRA ability to assess arterial occlusion, cerebral hemodynamics, and collateral circulation in acute ischemic stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>\n              Twenty-five acute ischemic stroke patients with proximal anterior circulation occlusion underwent dMRA on a 3T scanner within 12 hours of symptoms onset. Diffusion weighted imaging,\n              <jats:italic>T<\/jats:italic>\n              <jats:sub>max<\/jats:sub>\n              6 s lesion volumes and hypoperfusion intensity ratio as volume of\n              <jats:italic>T<\/jats:italic>\n              <jats:sub>max<\/jats:sub>\n              &gt;6 s\/volume of\n              <jats:italic>T<\/jats:italic>\n              <jats:sub>max<\/jats:sub>\n              &gt;10 s were measured. Site and grade of occlusion (Thrombolysis in Myocardial Infarction criteria) were evaluated on time-of-flight MRA and dMRA. Leptomeningeal collaterality (American Society of Interventional and Therapeutic Neuroradiology\/Society of Interventional Radiology [ASITN\/SIR] Scale) and asymmetries in venous clearance were assessed exclusively on dMRA. Collateral filling was dichotomized into incomplete (ASITN\/SIR 0\u20132) or complete (ASITN\/SIR 3\u20134).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              On dMRA, site of occlusion was M1 in 21 patients, tandem internal carotid artery\/M1 in 2 and tandem internal carotid artery\/terminal internal carotid artery in 2 patients. Three tandem occlusions were not detected on time-of-flight\u2013MRA. All patients had Thrombolysis in Myocardial Infarction 0 to 1 on time-of-flight\u2013MRA, but three of them had Thrombolysis in Myocardial Infarction 2 on dMRA. Complete collateral filling (n=12, 48%) was associated with smaller diffusion weighted imaging lesion volume (\n              <jats:italic>P<\/jats:italic>\n              =0.039), smaller hypoperfused volume (\n              <jats:italic>P<\/jats:italic>\n              =0.018), and lower hypoperfusion intensity ratio (\n              <jats:italic>P<\/jats:italic>\n              =0.006). Patients with symmetrical clearance of transverse sinuses (52%) were more likely to have complete collateral filling (\n              <jats:italic>P<\/jats:italic>\n              =0.015).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>As a fast, direct, feasible, noninvasive, and reliable method to assess site of occlusion, collateral circulation and hemodynamic alterations, dMRA provides profound insights in acute stroke.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.115.010748","type":"journal-article","created":{"date-parts":[[2015,12,13]],"date-time":"2015-12-13T07:24:34Z","timestamp":1449991474000},"page":"531-534","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":38,"title":["Dynamic Magnetic Resonance Angiography Provides Collateral Circulation and Hemodynamic Information in Acute Ischemic Stroke"],"prefix":"10.1161","volume":"47","author":[{"given":"Mar\u00eda","family":"Hern\u00e1ndez-P\u00e9rez","sequence":"first","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Puig","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Blasco","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"P\u00e9rez de la Ossa","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Dorado","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"D\u00e1valos","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Munuera","sequence":"additional","affiliation":[{"name":"From the Stroke Unit (M.H.-P., N.P.O., L.D., A.D.) and Diagnostic Imaging Institute (J.M.), Germans Trias i Pujol University Hospital, UAB, Badalona, Spain; and Department of Radiology, IDIBGI Diagnostic Imaging Institute, Dr Josep Trueta University Hospital, Girona, Spain (J.P., G.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.595256"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.003857"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.008648"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-2051-9"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24211"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.520593"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.115.010748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:27:03Z","timestamp":1715610423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.115.010748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1161\/STROKEAHA.115.010748"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.115.010748","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"2015-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-12-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}