{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T14:33:18Z","timestamp":1776954798919,"version":"3.51.4"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>The characteristics of infarctions restricted to the dorsal medulla have received little attention. This study aimed to define the distinct clinical features of dorsal medullary infarction.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>Of the 172 patients with a diagnosis of medullary infarction at Seoul National University Bundang Hospital from 2003 to 2014, 18 patients with isolated dorsal medullary infarction were subjected to analyses of clinical and laboratory findings.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>All patients presented acute isolated vestibular syndrome with dizziness\/vertigo and imbalance. Almost all patients (17\/18, 94%) showed the signs from involvements of the vestibular nuclei, nucleus prepositus hypoglossi, or inferior cerebellar peduncle, which included direction-changing gaze-evoked nystagmus (n=12), negative head-impulse tests (n=8), skew deviation (n=7), central patterns of head-shaking nystagmus (n=6), and spontaneous nystagmus (n=2). Initial magnetic resonance imagings including diffusion-weighted images were negative in 7 patients (39%). Twelve patients (67%) showed a progression and developed additional neurological abnormalities, but the neurological outcomes were favorable.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>The presence of central vestibular signs allows bedside differentiation of isolated vestibular syndrome because of dorsal medullary infarction from acute peripheral vestibular disorders. Because initially false-negative magnetic resonance imagings and subsequent progression are frequent in dorsal medullary infarction, early recognition through scrutinized evaluation is important for proper managements.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.115.010972","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T02:58:52Z","timestamp":1444791532000},"page":"3081-3087","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":70,"title":["Dorsal Medullary Infarction"],"prefix":"10.1161","volume":"46","author":[{"given":"Sun-Uk","family":"Lee","sequence":"first","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong-Ho","family":"Park","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong-Jin","family":"Park","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moon-Ku","family":"Han","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Joon","family":"Bae","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (S.-H.P., M.-K.H., H.-J.B., J.-S.K.); Department of Radiology, Samsung Medical Center, Seoul, South Korea (J.-J.P.); and Department of Biomedical Laboratory Science, Kyungdong University, Goseong-Gun, Gangwon-do, Korea (H.J.K.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea (S.-U.L.); 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