{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:45:38Z","timestamp":1778679938392,"version":"3.51.4"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Posterior circulation ischemic stroke (IS) is generally considered an illness with a poor prognosis. However, there are no effective rating scales to predict recurrent stroke following it. Therefore, our aim was to identify clinical or radiological measures that could assist in predicting recurrent cerebral ischemic episodes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>We prospectively enrolled 723 noncardiogenic posterior circulation IS patients with onset of symptoms &lt;7 days. Stroke risk factors, admission symptoms and signs, topographical distribution and responsible cerebral artery of acute infarcts, and any recurrent IS or transient ischemic attack (TIA) within 1 year were assessed. Cox regression was used to identify risk factors associated with recurrent IS or TIA within the year after posterior circulation IS.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              A total of 40 patients (5.5%) had recurrent IS or TIA within 1 year of posterior circulation IS. Multivariate Cox regression identified chief complaint with dysphagia (hazard ratio [HR], 4.16; 95% confidence interval [CI], 1.69\u201310.2;\n              <jats:italic>P<\/jats:italic>\n              =0.002), repeated TIAs within 3 months before the stroke (HR, 15.4; 95% CI, 5.55\u201342.5;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001), responsible artery stenosis \u226570% (HR, 7.91; 95% CI, 1.00\u201362.6;\n              <jats:italic>P<\/jats:italic>\n              =0.05), multisector infarcts (HR, 5.38; 95% CI, 1.25\u201323.3;\n              <jats:italic>P<\/jats:italic>\n              =0.02), and not on antithrombotics treatment at discharge (HR, 3.06; 95% CI, 1.09\u20138.58;\n              <jats:italic>P<\/jats:italic>\n              =0.03) as independent predictors of recurrent IS or TIA.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Some posterior circulation IS patients are at higher risk for recurrent IS or TIA. Urgent assessment and preventive treatment should be offered to these patients as soon as possible.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.116.016285","type":"journal-article","created":{"date-parts":[[2017,6,17]],"date-time":"2017-06-17T00:55:24Z","timestamp":1497660924000},"page":"1835-1841","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Prediction of Recurrent Stroke or Transient Ischemic Attack After Noncardiogenic Posterior Circulation Ischemic Stroke"],"prefix":"10.1161","volume":"48","author":[{"given":"Changqing","family":"Zhang","sequence":"first","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilong","family":"Wang","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingquan","family":"Zhao","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Liu","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ChunXue","family":"Wang","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuehua","family":"Pu","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinying","family":"Zou","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuesong","family":"Pan","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ka Sing","family":"Wong","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjun","family":"Wang","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, China (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing (C.Z., Yilong Wang, X.Z., L.L., C.W., Y.P., X.Z., Y.P., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yongjun Wang); and..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000097047"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.521419"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.2.456"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2012.00841.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181ca9cff"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5443-5"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000113732"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg197"},{"key":"e_1_3_3_11_2","first-page":"643","article-title":"A standardized method for measuring intracranial arterial stenosis.","volume":"21","author":"Samuels OB","year":"2000","unstructured":"Samuels OB, Joseph GJ, Lynn MJ, Smith HA, Chimowitz MI. 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