{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:23:53Z","timestamp":1792110233987,"version":"4.4.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Carotid webs have been increasingly recognized as a cause of recurrent stroke, but evidence remains scarce. We aim to report the clinical outcomes and first series of carotid stenting in a cohort of patients with strokes from symptomatic carotid webs.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>Prospective and consecutive data of patients &lt;65 years old with cryptogenic stroke admitted within September 2014 to May 2017. Carotid web was defined by a shelf-like\/linear filling defect in the posterior internal carotid artery bulb by computed tomographic angiography.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>\n              Twenty-four patients were identified (91.6% strokes\/8.4% transient ischemic attacks [TIAs]). Median age was 46 (41\u201359) years, 61% were female, and 75% were black. Median National Institutes of Health Stroke Scale score was 10.5 (3.0\u201316.0) and ASPECTS (Alberta Stroke Program Early CT Score) was 8 (7\u20138). There were no parenchymal hemorrhages, and 96% of patients were independent at 3 months. All webs caused &lt;50% stenosis. In patients with bilateral webs (58%), median ipsilateral web length was larger than contralateral (3.1 [3.0\u20134.5] mm versus 2.6 [1.85\u20132.9] mm;\n              <jats:italic>P<\/jats:italic>\n              =0.01), respectively. Twenty-nine percent of patients had thrombus superimposed on the symptomatic carotid web. A recurrent stroke\/TIA involving the territory of the previously symptomatic web occurred in 7 (32%; 6 strokes\/1 TIA) patients: 3 &lt;1 week, 2 &lt;first year, and 3 &gt;1 year of follow-up. Two recurrences occurred on dual antiplatelet therapy, 3 on antiplatelet monotherapy, 1 within 24 hours of thrombolysis, and 1 off antithrombotics. Median follow-up was 12.2 (8.0\u201318.0) months. Sixteen (66%) patients were stented at a median 12.2 (7.0\u201318.7) days after stroke with no periprocedural complications. No recurrent strokes\/TIAs occurred in stented individuals (median follow-up of 4 [2.4\u201312.0] months).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Carotid web is associated with high recurrent stroke\/TIA risk, despite antithrombotic use, and is amenable to carotid stenting.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.117.019020","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T00:10:29Z","timestamp":1507680629000},"page":"3134-3137","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":201,"title":["Carotid Web (Intimal Fibromuscular Dysplasia) Has High Stroke Recurrence Risk and Is Amenable to Stenting"],"prefix":"10.1161","volume":"48","author":[{"given":"Diogo C.","family":"Haussen","sequence":"first","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Grossberg","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Bouslama","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Pradilla","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Belagaje","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Bianchi","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason W.","family":"Allen","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Frankel","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul G.","family":"Nogueira","sequence":"additional","affiliation":[{"name":"From the Emory University\/Grady Memorial Hospital, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12418"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003464"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196803000-00021"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.8.5.617"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410060120"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1981.54.5.0685"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00878882"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.4.883"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.007313"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.013918"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.1.94"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5208"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4431"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.117.019020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T14:46:29Z","timestamp":1715611589000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.117.019020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1161\/STROKEAHA.117.019020"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.117.019020","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"2017-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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