{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:23:36Z","timestamp":1789809816750,"version":"4.0.1"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Purpose\u2014<\/jats:title>\n                    <jats:p>We aimed at providing estimates of mortality associated with cardiometabolic comorbidity and incident readmission from cardiometabolic as compared with noncardiometabolic conditions after a first transient ischemic attack.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods\u2014<\/jats:title>\n                    <jats:p>Between 2000 and 2015, patients hospitalized for a first transient ischemic attack were examined for cardiometabolic comorbidities (diabetes mellitus, coronary artery disease, heart failure, and atrial fibrillation), 5-year incident hospitalization, and time to death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results\u2014<\/jats:title>\n                    <jats:p>\n                      Of 251 patients with transient ischemic attack, 134 (53%) had at least 1 and 55 (22%) had at least 2 cardiometabolic conditions. By 5 years, 491 readmissions (134 [27%] cardiometabolic and 357 [73%] noncardiometabolic) and 75 deaths (27 [36%] cardiometabolic and 47 [64%] noncardiometabolic) were observed. Mortality was increased with any concurrent cardiometabolic comorbidity (hazard ratio, 1.89; 95% confidence interval, 1.17\u20133.03;\n                      <jats:italic>P<\/jats:italic>\n                      =0.0089) with multiplicative mortality risk from a combination of coronary artery disease and heart failure. Each hospitalization was associated with a 1.5-fold risk of death (95% confidence interval, 1.37\u20131.64;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.0001). Risk of cardiometabolic and noncardiometabolic mortality was correlated with the corresponding category-specific readmission.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>Among patients hospitalized for first transient ischemic attack, 5-year mortality is associated with concurrent cardiometabolic comorbidity and rates of subsequent hospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.117.020022","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T05:05:15Z","timestamp":1516079115000},"page":"730-733","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Five-Year Mortality After Transient Ischemic Attack"],"prefix":"10.1161","volume":"49","author":[{"given":"Mohammed","family":"Yousufuddin","sequence":"first","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Young","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Keenan","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy","family":"Olson","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Shultz","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Doyle","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eimad M.","family":"Ahmmad","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kogulavadanan","family":"Arumaithurai","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Takahashi","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hassan","family":"Murad","sequence":"additional","affiliation":[{"name":"From the Division of Internal Medicine, Mayo Clinic Health System, Austin, MN (M.Y., L.K., T.O., J.S., T.D., E.M.A., K.A.); and Division of Internal Medicine, Mayo Clinic, Rochester, MN (N.Y., P.T., M.H.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.636233"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000152"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.01.015"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.7008"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-15-90"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.05.001"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412981"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.333"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.01.041"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.117.020022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:57:15Z","timestamp":1715597835000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.117.020022"}},"subtitle":["Focus on Cardiometabolic Comorbidity and Hospital Readmission"],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1161\/STROKEAHA.117.020022"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.117.020022","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"2017-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}