{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:01:50Z","timestamp":1769126510471,"version":"3.49.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n            <jats:title>Background and Purpose\u2014<\/jats:title>\n            <jats:p>Despite evidence to support the prescription of antihypertensive medications before hospital discharge to promote medication adherence and prevent recurrent events, many patients with stroke miss out on these medications at discharge. We aimed to examine patient, clinical, and system-level differences in the prescription of antihypertensive medications at hospital discharge after stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods\u2014<\/jats:title>\n            <jats:p>\n              Adults with acute ischemic stroke or intracerebral hemorrhage alive at discharge were included (years 2009\u20132013) from 39 hospitals participating in the Australian Stroke Clinical Registry. Patient comorbidities were identified using the\n              <jats:italic>International Statistical Classification of Diseases and Related Health Problems (Tenth Edition, Australian Modification<\/jats:italic>\n              ) codes from the hospital admissions and emergency presentation data. The outcome variable and other system factors were derived from the Australian Stroke Clinical Registry dataset. Multivariable, multilevel logistic regression was used to examine factors associated with the prescription of antihypertensive medications at hospital discharge.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results\u2014<\/jats:title>\n            <jats:p>Of the 10\u2009315 patients included, 79.0% (intracerebral hemorrhage, 74.1%; acute ischemic stroke, 79.8%) were prescribed antihypertensive medications at discharge. Prescription varied between hospital sites, with 6 sites &gt;2 SDs below the national average for provision of antihypertensives at discharge. Prescription was also independently associated with patient and clinical factors including history of hypertension, diabetes mellitus, management in an acute stroke unit, and discharge to rehabilitation. In patients with acute ischemic stroke, females (odds ratio, 0.85; 95% CI, 0.76\u20130.94), those who had greater stroke severity (odds ratio, 0.81; 95% CI 0.72\u20130.92), or dementia (odds ratio, 0.65; 95% CI, 0.52\u20130.81) were less likely to be prescribed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Prescription of antihypertensive medications poststroke varies between hospitals and according to patient factors including age, sex, stroke severity, and comorbidity profile. Implementation of targeted quality improvement initiatives at local hospitals may help to reduce the variation in prescription observed.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.119.026823","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T09:00:17Z","timestamp":1571994017000},"page":"3592-3599","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Disparities in Antihypertensive Prescribing After Stroke"],"prefix":"10.1161","volume":"50","author":[{"given":"Lachlan L.","family":"Dalli","sequence":"first","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joosup","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda G.","family":"Thrift","sequence":"additional","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine E.","family":"Andrew","sequence":"additional","affiliation":[{"name":"Peninsula Clinical School, Central Clinical School (N.E.A.), Monash University, Clayton, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha A.","family":"Lannin","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourn, VIC, Australia (N.A.L.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig S.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Royal Prince Alfred Hospital, Camperdown, NSW, Australia (C.S.A.)"},{"name":"The George Institute for Global Health at Peking University Health Science Center, China (C.S.A.)"},{"name":"The George Institute for Global Health, Sydney, NSW, Australia (C.S.A.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohan","family":"Grimley","sequence":"additional","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"},{"name":"Sunshine Coast Clinical School, University of Queensland, Birtinya, QLD, Australia (R.G.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith M.","family":"Katzenellenbogen","sequence":"additional","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"},{"name":"Stroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia (J.M.K., D.A.C., M.F.K.)"},{"name":"School of Population and Global Health (J.M.K.), The University of Western Australia, Perth, Australia"},{"name":"Telethon Kids Institute (J.M.K.), The University of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Boyd","sequence":"additional","affiliation":[{"name":"School of Psychology and Public Health, La Trobe University, Bundoora, VIC, Australia (J.B.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard I.","family":"Lindley","sequence":"additional","affiliation":[{"name":"The University of Sydney, NSW, Australia (R.I.L.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Pollack","sequence":"additional","affiliation":[{"name":"Hunter Stroke Service, Hunter New England Health, NSW, Australia (M.P.)"},{"name":"The University of Newcastle, NSW, Australia (M.P.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Jude","sequence":"additional","affiliation":[{"name":"Wagga Wagga Hospital, NSW, Australia (M.J.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh","family":"Durairaj","sequence":"additional","affiliation":[{"name":"Cairns Base Hospital, QLD, Australia (R.D.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darshan","family":"Shah","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital, Brisbane, QLD, Australia (D.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique A.","family":"Cadilhac","sequence":"additional","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"},{"name":"Stroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia (J.M.K., D.A.C., M.F.K.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique F.","family":"Kilkenny","sequence":"additional","affiliation":[{"name":"From the Stroke and Ageing Research Group, Department of Medicine, School of Clinical Sciences at Monash Health (L.L.D., J.M.K., A.G.T., R.G., D.A.C., M.F.K.), Monash University, Clayton, VIC, Australia"},{"name":"Stroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia (J.M.K., D.A.C., M.F.K.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Stroke123 Investigators and the AuSCR Consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000116183.50167.D9"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30506-2"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000226212.34055.86"},{"key":"e_1_3_4_5_2","unstructured":"National Vascular Disease Prevention Alliance. Guidelines for the management of absolute cardiovascular disease risk. 2012. Available at: www.informme.org.au\/Guidelines. Accessed June 1 2019."},{"key":"e_1_3_4_6_2","unstructured":"Stroke Foundation. Clinical guidelines for stroke management 2010. Melbourne Australia. Available at: www.informme.org.au\/Guidelines. Accessed June 1 2019."},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000069"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy339"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.003368"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005023"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-013-9908-3"},{"key":"e_1_3_4_12_2","unstructured":"Cadilhac DA Lannin NA Anderson CS Andrew NE Kim J Kilkenny M et al. The Australian Stroke Clinical Registry Annual Report 2013. Available at: www.auscr.com.au\/auscr\/annual-reports\/. Accessed March 29 2018."},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000177522.80092.b7"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2010.00430.x"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.12029"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afx005"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/hs0402.105909"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.12.013"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000062"},{"key":"e_1_3_4_21_2","unstructured":"Australian Bureau of Statistics. Socio-Economic Indexes For Areas: Robustness Diversity Within Larger Areas and the New Geography Standard 2012. Available at:www.abs.gov.au\/AUSSTATS\/abs@.nsf\/DetailsPage\/1351.0.55.038Mar%202012. Accessed June 28 2019."},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-4356(00)00314-0"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/1753-6405.12576"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000442009.06663.48"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2018.7171"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1159\/000484141"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30233-3"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.0020"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-017-9906-0"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011971.pub2"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.21442"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000125709.17337.5d"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.015714"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f657"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023075"},{"key":"e_1_3_4_36_2","unstructured":"Stroke Foundation. National Stroke Audit Acute Services\u2013 Clinical Audit Report 2013. Available at: www.informme.org.au\/-\/media\/95C36BDF7A4849E8B0E009BDA647ECDD. Accessed September 13 2019."}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.119.026823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T15:27:18Z","timestamp":1715614038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.119.026823"}},"subtitle":["Linked Data From the Australian Stroke Clinical Registry"],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1161\/STROKEAHA.119.026823"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.119.026823","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"2019-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}