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Chronic kidney disease frequently complicates routine stroke risk prediction, diagnosis, management, and prevention. It is also associated with worse stroke severity, outcomes and a high burden of silent cerebrovascular disease, and vascular cognitive impairment. Here, we present a summary of the epidemiology, pathophysiology, diagnosis, and treatment of cerebrovascular disease in chronic kidney disease from the Kidney Disease: Improving Global Outcomes Controversies Conference on central and peripheral arterial disease with a focus on knowledge gaps, areas of controversy, and priorities for research.<\/jats:p>","DOI":"10.1161\/strokeaha.120.029680","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T05:07:50Z","timestamp":1622696870000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":144,"title":["Chronic Kidney Disease and Cerebrovascular Disease"],"prefix":"10.1161","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4318-2030","authenticated-orcid":true,"given":"Dearbhla M.","family":"Kelly","sequence":"first","affiliation":[{"name":"Wolfson Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, 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