{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:55:29Z","timestamp":1787018129178,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Aspiration catheters (ASPs) and stentriever thrombectomy devices have comparable safety and efficacy in anterior circulation ischemic strokes. However, there is lack of high-quality comparative data in acute basilar artery occlusions. Our objective is to compare the outcomes and safety of ASPs and stentriever devices in acute basilar artery occlusions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>This is an analysis of the retrospectively established PC-SEARCH Thrombectomy (Posterior-Circulation Ischemic Stroke Evaluation: Analyzing Radiographic and Intraprocedural Predictors for Mechanical Thrombectomy) registry. Patients were dichotomized based on their first-line thrombectomy device (ASP and stentriever) and associated with their 90-day functional outcomes, intraprocedural metrics, and safety measures. Propensity analysis based on unequal baseline characteristics was performed. Consecutive patients with acute basilar artery occlusions who received mechanical thrombectomy were included from January 2015 to December 2021. Patients received either first-line contact aspiration or stentriever mechanical thrombectomy. Primary clinical and safety outcomes were 90-day functional independence measured by a modified Rankin Scale score of 0 to 3 and symptomatic intracranial hemorrhage, respectively. Secondary outcomes included puncture-recanalization times, first-pass recanalization rates, crossovers to other thrombectomy device, and neurological\/hospital complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Five hundred eighteen patients were included in the registry, and a total of 383 patients were included (mean [SD] age, 65.5 [15] years; 228 [59%] men) in this analysis. Of these, 219 patients were first-line ASP while 164 patients received first-line stentriever devices. Median premorbid modified Rankin Scale was zero and median presenting National Institutes of Health Stroke Scale was 17 (interquartile range, 8\u201326). The proportion of favorable functional outcome was similar between the 2 techniques before (47.3% versus 42.5%; odds ratio, 1.22 [95% CI, 0.78\u20131.89];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.38) and after propensity matching (odds ratio, 1.46 [95% CI, 0.85\u20132.49];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.17). In our propensity-matched cohorts, puncture-recanalization times (18 versus 52 minutes;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01) favored first-line ASP; however, first-pass recanalization rates (43.5% versus 44.5%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.90) were similar between groups. First-line ASP was associated with higher rates of crossover (22% versus 6%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01), whereas stentriever was associated with higher rates of symptomatic intracranial hemorrhage (9.8% versus 3.4%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>First-line ASP and stentriever methods demonstrated similar functional outcome and recanalization rates. Stentriever methods were associated with higher rates of symptomatic intracranial hemorrhage, whereas ASPs were associated with higher rates of crossover to alternative technique in patients with acute basilar occlusions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.123.043579","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T14:00:43Z","timestamp":1695650443000},"page":"2512-2521","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Comparing Functional Outcomes and Safety Profiles of First-Line Aspiration Thrombectomy Versus Stentriever for Acute Basilar Artery Occlusion: Propensity Analysis of the PC-SEARCH Thrombectomy Registry"],"prefix":"10.1161","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7750-1132","authenticated-orcid":true,"given":"Adam T.","family":"Mierzwa","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Toledo College of Medicine and Life Sciences, OH (A.T.M., N.A., K.G., E.A., S.Z., M.J.)."},{"name":"Promedica Stroke Network, Toledo, OH (A.T.M., E.A., S.Z., M.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8909-9761","authenticated-orcid":true,"given":"Sami","family":"Al Kasab","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, Medical University of South Carolina, Charleston (S.A.K., A.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8632-8570","authenticated-orcid":true,"given":"Ashley","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurosurgery, Medical University of South Carolina, Charleston (S.A.K., A.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3408-1297","authenticated-orcid":true,"given":"Santiago","family":"Ortega Gutierrez","sequence":"additional","affiliation":[{"name":"University of Iowa, Iowa City (S.O.G., J.V.-S., M.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5326-1907","authenticated-orcid":true,"given":"Juan","family":"Vivanco-Suarez","sequence":"additional","affiliation":[{"name":"University of Iowa, Iowa City (S.O.G., J.V.-S., M.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3697-5697","authenticated-orcid":true,"given":"Mudassir","family":"Farooqui","sequence":"additional","affiliation":[{"name":"University of Iowa, Iowa City (S.O.G., J.V.-S., M.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9454-0678","authenticated-orcid":true,"given":"Ashutosh P.","family":"Jadhav","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Pittsburgh Medical Center, PA (A.P.J., S.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9013-6929","authenticated-orcid":true,"given":"Shashvat","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Pittsburgh Medical Center, PA (A.P.J., S.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-3635","authenticated-orcid":true,"given":"Gabor","family":"Toth","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Foundation, OH (G.T., A.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7601-6920","authenticated-orcid":true,"given":"Anas","family":"Alrohimi","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Foundation, OH (G.T., A.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-1685","authenticated-orcid":true,"given":"Thanh N.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Radiology, Boston University Chobanian and Avedisian School of Medicine, MA (T.N.N., P.K., M.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7468-137X","authenticated-orcid":true,"given":"Piers","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Neurology, Radiology, Boston University Chobanian and Avedisian School of Medicine, MA (T.N.N., P.K., M.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9528-301X","authenticated-orcid":true,"given":"Mohamad","family":"Abdalkader","sequence":"additional","affiliation":[{"name":"Department of Neurology, Radiology, Boston University Chobanian and Avedisian School of Medicine, MA (T.N.N., P.K., 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Toledo College of Medicine and Life Sciences, OH (A.T.M., N.A., K.G., E.A., S.Z., M.J.)."},{"name":"Promedica Stroke Network, Toledo, OH (A.T.M., E.A., S.Z., M.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4967-1801","authenticated-orcid":true,"given":"Syed","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Toledo College of Medicine and Life Sciences, OH (A.T.M., N.A., K.G., E.A., S.Z., M.J.)."},{"name":"Promedica Stroke Network, Toledo, OH (A.T.M., E.A., S.Z., M.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7165-797X","authenticated-orcid":true,"given":"Mouhammad","family":"Jumaa","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Toledo College of Medicine and Life Sciences, OH (A.T.M., N.A., K.G., E.A., S.Z., M.J.)."},{"name":"Promedica Stroke Network, Toledo, OH (A.T.M., E.A., S.Z., 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