{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:41:28Z","timestamp":1780591288497,"version":"3.54.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>The presence of antiphospholipid antibodies (aPL) has been suggested as a potential cause of moyamoya angiopathy (MMA), but this remains uncertain. In this case-control study, we aimed to compare the prevalence of circulating aPL in patients with MMA and in non-MMA cerebrovascular controls.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>For comparison, we included 95 patients with MMA from the French National Referral Centre for this condition and 182 age- and sex-matched non-MMA controls with a different cerebrovascular disease, all younger than 55 years. Anticardiolipin antibodies, anti-\u03b22-glycoprotein I antibodies, and lupus anticoagulant were assessed using the guidelines of the International Society on Thrombosis and Haemostasis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              aPL prevalence was 22% in patients with MMA and 25% in controls (\n              <jats:italic>P<\/jats:italic>\n              =0.74) with no differences in aPL subtypes between the 2 groups. The prevalence of transient ischemic attacks, ischemic stroke, and hemorrhagic stroke did not differ between patients with aPL-positive and aPL-negative MMA.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>The prevalence of aPL in patients with MMA is comparable to that in non-MMA controls. The present results do not support any causal relationship between aPL and MMA.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/strokeaha.124.048852","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T10:00:16Z","timestamp":1733738416000},"page":"190-193","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Moyamoya Angiopathy and Antiphospholipid Antibodies: A Coincidental Association?"],"prefix":"10.1161","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0465-6659","authenticated-orcid":true,"given":"Lina","family":"Grosset","sequence":"first","affiliation":[{"name":"APHP-H\u00f4pital Lariboisi\u00e8re-CERVCO, INSERM-U1141, FHU-NeuroVasc-Universit\u00e9 Paris-Cit\u00e9, France (L.G., H.C., D.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2942-0901","authenticated-orcid":true,"given":"Alain","family":"Stepanian","sequence":"additional","affiliation":[{"name":"CHU de Montpellier, Universit\u00e9 de Montpellier, PhyMedExp Inserm CNRS, France (A.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3224-7994","authenticated-orcid":true,"given":"Marc-Antoine","family":"Labeyrie","sequence":"additional","affiliation":[{"name":"APHP-Nord-H\u00f4pital Lariboisi\u00e8re, Neuroradiologie interventionnelle, INSERM-U942, Paris, France (M.-A.L., V.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Civelli","sequence":"additional","affiliation":[{"name":"APHP-Nord-H\u00f4pital Lariboisi\u00e8re, Neuroradiologie interventionnelle, INSERM-U942, Paris, France (M.-A.L., V.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8436-6074","authenticated-orcid":true,"given":"Hugues","family":"Chabriat","sequence":"additional","affiliation":[{"name":"APHP-H\u00f4pital Lariboisi\u00e8re-CERVCO, INSERM-U1141, FHU-NeuroVasc-Universit\u00e9 Paris-Cit\u00e9, France (L.G., H.C., D.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6509-8964","authenticated-orcid":true,"given":"Virginie","family":"Siguret","sequence":"additional","affiliation":[{"name":"APHP-Nord-H\u00f4pital Lariboisi\u00e8re, H\u00e9matologie Biologique, INSERM-U1140, Paris, France (V.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6197-6275","authenticated-orcid":true,"given":"Dominique","family":"Herv\u00e9","sequence":"additional","affiliation":[{"name":"APHP-H\u00f4pital Lariboisi\u00e8re-CERVCO, INSERM-U1141, FHU-NeuroVasc-Universit\u00e9 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