{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:46:03Z","timestamp":1792014363940,"version":"4.4.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>The long-term benefits of endovascular thrombectomy (EVT) for basilar artery occlusion (BAO) in patients with low National Institutes of Health Stroke Scale scores upon admission remain unclear. This study aimed to compare the 1-year clinical follow-up outcomes of best medical management (BMM) alone versus BMM plus EVT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Patients with BAO and admission National Institutes of Health Stroke Scale score of \u226410 at 65 stroke centers in China from December 2015 to June 2022 were retrospectively enrolled. The primary outcome was favorable functional outcome (a modified Rankin Scale score of 0\u20133 at 1 year). Early (door-to-puncture time \u2264120 minutes) and late EVT (door-to-puncture time &gt;120 minutes) classifications were defined as surrogates for comparing initial treatment with EVT versus late (potentially rescue) EVT after initially being treated with BMM only. Multivariable logistic regression and propensity score matching analyses were used to assess the association between treatment and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Among 1232 patients who had 1-year follow-up data, 856 (69.5%) were men, and the mean (SD) age was 65 (12) years. After adjustment for confounders, there were no significant differences between EVT and BMM in favorable functional outcome (odds ratio, 0.96 [95% CI, 0.71\u20131.29];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.778). The cumulative 1-year mortality rate was 16.4% in the EVT group versus 13.7% in the BMM group (odds ratio, 1.23 [95% CI, 0.86\u20131.77];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.262). Predefined subgroup analyses revealed that late EVT was inferior to early EVT (odds ratio, 0.47 [95% CI, 0.28\u20130.79];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.005), while no significant difference was observed between BMM and early EVT in 1-year outcomes (odds ratio, 0.87 [95% CI, 0.63\u20131.21];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.421).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In this long-term follow-up study among patients with BAO admitted with a National Institutes of Health Stroke Scale score of \u226410, there were no significant differences in functional outcomes and mortality at 1 year between BMM plus EVT and BMM alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.124.050389","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T05:01:56Z","timestamp":1745557316000},"page":"2122-2134","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["One-Year Outcome After Endovascular Thrombectomy for Basilar Artery Occlusion With Mild Deficits"],"prefix":"10.1161","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4181-7450","authenticated-orcid":true,"given":"Yingjie","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. Sun)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5942-0902","authenticated-orcid":true,"given":"Lulu","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, China (L.X.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6320-6987","authenticated-orcid":true,"given":"Pan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. Sun)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiliang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Haiyan County People\u2019s Hospital, Jiaxing, China (W. Shi)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shidong","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, China (S.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1821-0534","authenticated-orcid":true,"given":"Miaomiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bengbu Medical College, Bengbu, China (M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6813-8589","authenticated-orcid":true,"given":"Zhanglin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. Sun)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. Sun)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0639-1695","authenticated-orcid":true,"given":"Wanqiu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. Sun)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuwei","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tongcheng City People\u2019s Hospital, China (W.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Xuzhou Central Hospital, China (L.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5662-4758","authenticated-orcid":true,"given":"Shuai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Affiliated Hospital of Yangzhou University, Yangzhou University, China (S.Z.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengfei","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zhong Mei Kuang Jian Zong Yi Yuan, Suzhou, China (S.Q.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglin","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Funan County People\u2019s Hospital, Fuyang, China (G.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongguang","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Neurology, The People\u2019s Hospital of Yingshang, Fuyang, China (H.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangxiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yingshang County Hospital of Traditional Chinese Medicine, Fuyang, China (X.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8957-8444","authenticated-orcid":true,"given":"Jie","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China (J.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0393-723X","authenticated-orcid":true,"given":"Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Xuzhou Medical University, China (H.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8182-9632","authenticated-orcid":true,"given":"Xinfeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Centre for Leading Medicine and Advanced Technologies of Institute of Health and Medicine (IHM), The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (Y.X., P.Z., Z.L., X.Z., W.Z., X.L., W. 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