{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:25:17Z","timestamp":1787757917095,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>The Fazekas score is widely used to grade white matter hyperintensities (WMHs) in cerebral small vessel disease, yet the equivalent volume of each grade is unclear. We quantified the correspondence between Fazekas scores and WMH volume, normalized ratios, and derived conversion equations across populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      We analyzed 1220 participants from 4 mostly United Kingdom\u2013based cohorts representing different cerebral small vessel disease severities: community-dwelling (LBC1936 [Lothian Birth Cohort 1936]), stroke (MSS2 [Mild Stroke Study 2] and MSS3 [Mild Stroke Study 3]), and a cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy-enriched cohort (INVESTIGATE [Imaging Neuro-Vascular, Endothelial and Structural Integrity in Preparation to Treat Small Vessel Diseases]). WMH burden was quantified as absolute WMH volume and as normalized ratios: WMH volume as a percentage of brain volume and WMH volume as a percentage of intracranial volume. Transition zones were defined as the overlap of WMH volume interquartile ranges between adjacent Fazekas scores. Linear, exponential (nonlinear least squares), and log-linear (ln WMH\u2248Fazekas score and zeros excluded) models were fitted; model fit was assessed using mean squared error, (pseudo-)R\n                      <jats:sup>2<\/jats:sup>\n                      , and Vuong tests. Periventricular-versus-deep WMH patterns within each total Fazekas score were compared using the Kruskal-Wallis test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The pooled cohort had a mean age of 69.4\u00b18.9 years; 700 of 1227 records (57.1%) were male. WMH burden increased monotonically with a Fazekas score in all cohorts. Adjacent-grade separation was strongest in LBC1936 (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u22640.002) but weaker at lower grades in MSS2, MSS3, and INVESTIGATE. The widest transition zones occurred between Fazekas grades of 3 to 4 and 4 to 5, whereas a clear WMH volume gap separated grades 5 and 6. Exponential models generally fit better than linear models, with lower mean squared error and supportive Vuong tests in most cohorts. Log-linear sensitivity analyses showed similar fitted trajectories after back-transformation. WMH burden did not differ consistently by periventricular-versus-deep distribution within Fazekas grades.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>WMH burden followed an exponential trajectory across Fazekas scores, with population-dependent progression. The resulting conversion equations enabled bidirectional translation between visual Fazekas score and quantitative WMH volume, facilitating cross-study comparison, large-scale epidemiology, and might facilitate clinical decision-making in cerebral small vessel disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.125.055101","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T09:00:51Z","timestamp":1784106051000},"page":"2801-2812","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI"],"prefix":"10.1161","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7109-1283","authenticated-orcid":true,"given":"Yu-Yuan","family":"Xu","sequence":"first","affiliation":[{"name":"China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University (Y.-Y.X.)."},{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7742-1757","authenticated-orcid":true,"given":"Francesca M.","family":"Chappell","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Valdes Hernandez","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2424-7123","authenticated-orcid":true,"given":"Carmen","family":"Arteaga Reyes","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8062-7537","authenticated-orcid":true,"given":"Una","family":"Clancy","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9457-9855","authenticated-orcid":true,"given":"Daniela","family":"Jaime Garcia","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8701-9043","authenticated-orcid":true,"given":"Stephen","family":"Makin","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"Centre for Rural Health, University of Aberdeen, United Kingdom (S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3811-4439","authenticated-orcid":true,"given":"Michael","family":"Stringer","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7858-9917","authenticated-orcid":true,"given":"Michael","family":"Thrippleton","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6739-5797","authenticated-orcid":true,"given":"Stewart","family":"Wiseman","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5227-9811","authenticated-orcid":true,"given":"Yajun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Neurology, West China Hospital, Sichuan University, Chengdu (Y.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3091-1932","authenticated-orcid":true,"given":"Dillys Xiaodi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, University of California, San Francisco (D.X.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7688-4864","authenticated-orcid":true,"given":"Rosalind","family":"Brown","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2769-3148","authenticated-orcid":true,"given":"Fergus","family":"Doubal","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian J.","family":"Deary","sequence":"additional","affiliation":[{"name":"Department of Psychology (I.J.D., S.C.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4036-3642","authenticated-orcid":true,"given":"Simon","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Psychology (I.J.D., S.C.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3359-0361","authenticated-orcid":true,"given":"Danielle","family":"Kerkhofs","sequence":"additional","affiliation":[{"name":"Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, the Netherlands (D.K., J.S., W.B., R.v.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9502-6937","authenticated-orcid":true,"given":"Julie","family":"Staals","sequence":"additional","affiliation":[{"name":"Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, the Netherlands (D.K., J.S., W.B., R.v.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7905-0681","authenticated-orcid":true,"given":"Walter","family":"Backes","sequence":"additional","affiliation":[{"name":"Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, the Netherlands (D.K., J.S., W.B., R.v.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1032-9099","authenticated-orcid":true,"given":"Robert","family":"van Oostenbrugge","sequence":"additional","affiliation":[{"name":"Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, the Netherlands (D.K., J.S., W.B., R.v.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5037-2342","authenticated-orcid":true,"given":"Anna","family":"Kopczak","sequence":"additional","affiliation":[{"name":"Institute for Stroke and Dementia Research, Ludwig-Maximilians Universit\u00e4t, Munich, Germany (A.K., M.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2302-3136","authenticated-orcid":true,"given":"Marco","family":"Duering","sequence":"additional","affiliation":[{"name":"Institute for Stroke and Dementia Research, Ludwig-Maximilians Universit\u00e4t, Munich, Germany (A.K., M.D.)."},{"name":"Medical Image Analysis Center (MIAC AG) and Department of Biomedical Engineering, University of Basel, Switzerland (M.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9812-6642","authenticated-orcid":true,"given":"Joanna M.","family":"Wardlaw","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."},{"name":"UK Dementia Research Institute (Y.-Y.X., F.M.C., M.V.H., C.A.R., U.C., D.J.G., S.M., M.S., M.T., S.W., R.B., F.D., J.M.W.), The University of Edinburgh, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70124-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(23)00131-X"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2019.01.002"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.149.2.351"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12021-015-9260-y"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.compmedimag.2021.101867"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1718-6"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022.106333"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000341859"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000123264.40498.b6"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000113863"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.01.018"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0193-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.07.048"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.124.046731"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-7-28"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.415"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/2396987320929617"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccb.2021.100020"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1017\/thg.2015.71"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.010665"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1053-8119(02)91132-8"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.906424"},{"key":"e_1_3_3_25_2","volume-title":"BET2: MR-Based Estimation of Brain, Skull and Scalp Surfaces","author":"Jenkinson M","year":"2005","unstructured":"Jenkinson M, P\u00e9chaud M, Smith S. BET2: MR-Based Estimation of Brain, Skull and Scalp Surfaces. In: Eleventh Annual Meeting of the Organization for Human Brain Mapping. 2005."},{"key":"e_1_3_3_26_2","first-page":"523","volume-title":"Identification of Cerebral Small Vessel Disease Using Multiple Instance Learning","author":"Chen L","year":"2015","unstructured":"Chen L, Tong T, Ho CP, Patel R, Cohen D, Dawson AC, Halse O, Geraghty O, Rinne PEM, White CJ, et al. Identification of Cerebral Small Vessel Disease Using Multiple Instance Learning. In: Machine Learning in Medical Imaging. 2015:523\u2013530."},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.2307\/1912557"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000202585.26325.74"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004490"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0371-x"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182749f02"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1159\/000226774"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.105764"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000209665"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/STROKEAHA.125.055101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:57:19Z","timestamp":1787756239000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.125.055101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":33,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1161\/STROKEAHA.125.055101"],"URL":"https:\/\/doi.org\/10.1161\/strokeaha.125.055101","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2025-12-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-03","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}