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Intensive behavioral interventions, including constraint-induced movement therapy and telerehabilitation, result in meaningful gains even in chronic stroke. Biological therapies\u2014growth factors, monoclonal antibodies, and stem cell approaches\u2014show promise but face translational challenges. Pharmacological strategies targeting serotonergic and dopaminergic systems have yielded mixed results. Neural stimulation approaches span a spectrum of invasiveness, with vagus nerve stimulation now Food and Drug Administration\u2013approved and emerging candidates including cerebellar deep brain stimulation and spinal cord epidural stimulation showing early promise. These studies have provided important lessons for neural repair trial design. Synthesizing evidence across modalities, we highlight how therapeutic advances are reshaping the landscape of poststroke recovery and identify the most promising opportunities for clinical translation. Emerging neural repair strategies stand to substantially improve function after stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/strokeaha.126.056092","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:00:12Z","timestamp":1791450012000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Neural Repair Therapies After Stroke: I. 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