{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:00:20Z","timestamp":1790283620240,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["SVIN"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">A better understanding of real\u2010world practice patterns in the endovascular treatment for large vessel occlusion acute ischemic stroke is needed. Here, we report the methods and initial results of the Society of Vascular and Interventional Neurology (SVIN) Registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">The SVIN Registry is an ongoing prospective, multicenter, observational registry capturing patients with large vessel occlusion acute ischemic stroke undergoing endovascular treatment since November 2018. Participating sites also contributed pre\u2010SVIN Registry data collected per institutional prospective registries, and these data were combined with the SVIN Registry in the SVIN Registry+ cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">There were 2088 patients treated across 11 US centers included in the prospective SVIN Registry and 5372 in SVIN Registry+. In the SVIN Registry cohort, the median number of enrollments per institution was 160 [interquartile range 53\u2013243]. Median age was 67 [58\u201379] years, 49% were women, median National Institutes of Health Stroke Scale 16 [10\u201321], Alberta stroke program early CT score 9 [7\u201310], and 20% had baseline modified Rankin scale (mRS)\u22652. The median last\u2010known normal to puncture time was 7.7 [3.1\u201311.5]\u00a0hours, and puncture\u2010to\u2010reperfusion was 33 [23\u201352]\u00a0minutes. The predominant occlusion site was the middle cerebral artery\u2010M1 (45%); medium vessel occlusions occurred in 97(4.6%) patients. The median number of passes was 1 [1\u20133] with 93% achieving expanded Treatment In Cerebral Ischemia2b50\u20133 reperfusion and 51% expanded Treatment In Cerebral Ischemia3\/complete reperfusion. Symptomatic intracranial hemorrhage occurred in 5.3% of patients, with 37.3% functional independence (mRS0\u20132) and 26.4% mortality rates at 90\u2010days. Multivariable regression indicated older age, longer last\u2010normal to reperfusion, higher baseline National Institutes of Health Stroke Scale and glucose, lower Alberta stroke program early CT score, heart failure, and general anesthesia associated with lower 90\u2010day chances of mRS0\u20132 at 90\u2010days. Demographic, imaging, procedural, and clinical outcomes were similar in the SVIN Registry+. A comparison between AHA Guidelines\u2010eligible patients from the SVIN Registry against the Highly Effective Reperfusion evaluated in Multiple Endovascular Stroke Trials study population demonstrated comparable clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">The prospective SVIN Registry demonstrates that satisfactory procedural and clinical outcomes can be achieved in real\u2010world practice, serving as a platform for local quality improvement and the investigation of unexplored frontiers in the endovascular treatment of acute stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/svin.121.000234","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T11:28:39Z","timestamp":1646738919000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":43,"title":["The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Methods and Primary Results"],"prefix":"10.1161","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1884-2196","authenticated-orcid":false,"given":"Diogo C.","family":"Haussen","sequence":"first","affiliation":[{"name":"Emory University School of Medicine\/Grady Memorial Hospital Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alhamza R.","family":"Al\u2010Bayati","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine\/Grady Memorial Hospital Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud H.","family":"Mohammaden","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine\/Grady Memorial Hospital Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil A.","family":"Sheth","sequence":"additional","affiliation":[{"name":"Department of Neurology UTHealth McGovern Medical School Houston TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Salazar\u2010Marioni","sequence":"additional","affiliation":[{"name":"Department of Neurology UTHealth McGovern Medical School Houston TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Italo","family":"Linfante","sequence":"additional","affiliation":[{"name":"Miami Cardiac &amp; Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Dabus","sequence":"additional","affiliation":[{"name":"Miami Cardiac &amp; Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy K.","family":"Starosciak","sequence":"additional","affiliation":[{"name":"Miami Cardiac &amp; Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ameer E.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Valley Baptist Neuroscience Institute University of Texas Rio Grande Valley Harlingen TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wondwossen G.","family":"Tekle","sequence":"additional","affiliation":[{"name":"Valley Baptist Neuroscience Institute University of Texas Rio Grande Valley Harlingen TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh N.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Boston Medical Center Boston University School of Medicine Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Abdalkader","sequence":"additional","affiliation":[{"name":"Boston Medical Center Boston University School of Medicine Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piers","family":"Klein","sequence":"additional","affiliation":[{"name":"Boston Medical Center Boston University School of Medicine Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Siegler","sequence":"additional","affiliation":[{"name":"Cooper Neurological Institute Cooper University Hospital Camden NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratit D.","family":"Patel","sequence":"additional","affiliation":[{"name":"Cooper Neurological Institute Cooper University Hospital Camden NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tudor G.","family":"Jovin","sequence":"additional","affiliation":[{"name":"Cooper Neurological Institute Cooper University Hospital Camden NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Ortega\u2010Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Iowa Hospitals and Clinics Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudassir","family":"Farooqui","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Iowa Hospitals and Clinics Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Zevallos","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Iowa Hospitals and Clinics Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahram","family":"Majidi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna T.","family":"Fifi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Matsoukas","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brijesh P.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Memorial Neuroscience Institute Pembroke Pines FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy E.","family":"Sessa","sequence":"additional","affiliation":[{"name":"Memorial Neuroscience Institute Pembroke Pines FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca M.","family":"Sugg","sequence":"additional","affiliation":[{"name":"University of South Alabama Medical Center Mobile AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Cordina","sequence":"additional","affiliation":[{"name":"University of South Alabama Medical Center Mobile AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Linares","sequence":"additional","affiliation":[{"name":"Souers Stroke Institute Saint Louis University School of Medicine St. Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weston R.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Souers Stroke Institute Saint Louis University School of Medicine St. Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouhammad A.","family":"Jumaa","sequence":"additional","affiliation":[{"name":"ProMedica Neurosciences Center University of Toledo\u2010College of Medicine &amp; Life Sciences Toledo OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Liebeskind","sequence":"additional","affiliation":[{"name":"Neurovascular Imaging Res Core, UCLA Los Angeles CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4532-153X","authenticated-orcid":false,"given":"Raul G.","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine\/Grady Memorial Hospital Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2018-014239"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706442"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1713973"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.5.604"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02237-6"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2018-014127"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804656"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.010049"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.613273"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.13647"},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jrsm.1429","article-title":"Optimally estimating the sample standard deviation from the five\u2010number summary","volume":"11","author":"Shi J","year":"2020","unstructured":"Shi J, Luo D, Weng H, Zeng XT, Lin L, Chu H, Tong T. Optimally estimating the sample standard deviation from the five\u2010number summary. Res Synth Methods. 2020;11:641\u2013654.","journal-title":"Res Synth Methods"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0962280216669183"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01341-6"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.10.034"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.016456"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.010867"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2020-017027"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2013-010895"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013328"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k949"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2018-014289"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.12.007"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0141571"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00062-020-00988-x"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019988"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028920"}],"container-title":["Stroke: Vascular and Interventional Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/SVIN.121.000234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T03:24:22Z","timestamp":1738812262000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/SVIN.121.000234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1161\/SVIN.121.000234"],"URL":"https:\/\/doi.org\/10.1161\/svin.121.000234","relation":{},"ISSN":["2694-5746"],"issn-type":[{"value":"2694-5746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"2021-10-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e000234"}}