{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T14:13:24Z","timestamp":1774620804148,"version":"3.50.1"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["SVIN"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">In addition to enlarging the catheter tip diameter, recent aspiration catheters were designed with a novel angled\u2010tip design. We aimed to evaluate the efficacy of new\u2010generation angled\u2010tip aspiration catheters in comparison to commonly used straight\u2010tip large\u2010bore aspiration catheters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We performed a multicenter retrospective analysis of consecutive cases with M1 occlusion treated with aspiration thrombectomy from July 2016 to February 2021. Patients were divided into 2 cohorts: those in whom a 0.071\u2010inch angled\u2010tip catheter was used and those in whom a 0.068\u2010 to 0.074\u2010inch flat\u2010tip catheter was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      A total of 384 patients were identified. The angled\u2010tip catheter was used in 129 (33.6%) patients, whereas 255 (66.4%) patients were treated with flat\u2010tip catheters. There was no significant difference in age, sex, baseline modified Rankin scale score, side of occlusion, initial National Institutes of Health Stroke Scale score, time from last known normal to access, or rate of intravenous recombinant tPA (tissue\u2010type plasminogen activator) administration. Use of the angled\u2010tip reperfusion catheter was associated with average 5\u2010minute faster time to Thrombolysis in Cerebral Infarction 2B or better (22.13\u00b121.05 versus 27\u00b124.54\u00a0minutes;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.012) and 7\u2010minute faster time to final recanalization (25.85\u00b125.22 versus 32.96\u00b129.26 minutes;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.011). There was no difference in the rate of good outcome or hemorrhagic transformation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">We report a multicenter, retrospective review of patients treated with current generation large\u2010bore aspiration catheters. Angled\u2010tipped catheters were associated with shorter times to Thrombolysis in Cerebral Infarction 2B and final reperfusion. There were no differences in 90\u2010day modified Rankin scale score, rates of intracranial hemorrhage, or complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/svin.122.000580","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T01:16:11Z","timestamp":1681866971000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Factors Associated With Improved Technical Outcomes When Using 0.068\u2010 to 0.074\u2010Inch Aspiration Catheters: Analysis From a Multicenter Retrospective Cohort"],"prefix":"10.1161","volume":"3","author":[{"given":"Jan","family":"Vargas","sequence":"first","affiliation":[{"name":"Prisma Health Upstate","place":["Greenville"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahram","family":"Majidi","sequence":"additional","affiliation":[{"name":"Mt. 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