{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:35:00Z","timestamp":1753889700426,"version":"3.41.2"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["SVIN"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec id=\"svi212929-sec-0010\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Limited evidence is available for the treatment of acute symptomatic subocclusive lesions in ischemic stroke. We sought to identify current treatment patterns of stroke teams at academic health centers.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"svi212929-sec-0020\" xml:lang=\"en\">\n            <jats:title>Methods<\/jats:title>\n            <jats:p xml:lang=\"en\">We conducted an email survey of the National Institutes of Health StrokeNet regional coordinating centers (RCCs). Each RCC principal investigator was asked to nominate a local stroke interventionalist, or a neurologist if the RCC principal investigator was an interventionalist, most aligned with the typical practice pattern of the RCC's lead hospital, to receive a survey. The survey consisted of a clinical vignette and displayed a subocclusive lesion in the left middle cerebral artery on computed tomography angiogram followed by subsequent scenarios, revising only 1 historical, clinical, or radiographic variable at a time. Participants were asked to select initial management for each scenario. Results were reviewed and analyzed by stroke\u2010trained physicians.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"svi212929-sec-0030\" xml:lang=\"en\">\n            <jats:title>Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Responses were received from 42 (77.8%) of 54 surveyed individuals, representing 25 (92.6%) of 27 RCCs nationwide, including 25 (59.5%) interventionalists. The majority (76.2%) of respondents treated the patient in the primary clinical vignette with mechanical thrombectomy. Among all 6 clinical scenarios, respondents chose mechanical thrombectomy with or without medical management as first\u2010line treatment for 4 (67%) vignettes. Exceptions were low National Institutes of Health Stroke Scale score and known ipsilateral stenosis, where respondents chose medical management as first\u2010line treatment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"svi212929-sec-0040\" xml:lang=\"en\">\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p xml:lang=\"en\">Despite limited evidence to support mechanical thrombectomy versus other treatment strategies, the majority of StrokeNet RCC respondents would use mechanical thrombectomy with or without medical therapy to treat acute ischemic stroke due to intracranial subocclusive lesions.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/svin.124.001367","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T04:46:34Z","timestamp":1715834794000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["First\u2010Line Treatment of Symptomatic Subocclusive Large\u2010Vessel Stroke: Results of a Nationwide StrokeNet Survey"],"prefix":"10.1161","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3515-4005","authenticated-orcid":false,"given":"Yasmin N.","family":"Aziz","sequence":"first","affiliation":[{"name":"University of Cincinnati","place":["Cincinnati"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Harker","sequence":"additional","affiliation":[{"name":"University of Cincinnati","place":["Cincinnati"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Ayala","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine Mount Sinai Elmhurst","place":["New York"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.C.","family":"Ades","sequence":"additional","affiliation":[{"name":"NYU Langone Health","place":["New York"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaibhav","family":"Vagal","sequence":"additional","affiliation":[{"name":"Renaissance School of Medicine at Stony Brook University","place":["Stony Brook"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Khatri","sequence":"additional","affiliation":[{"name":"University of Cincinnati","place":["Cincinnati"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/strokeaha.108.526277"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023015"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000211"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2011-010134"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011743"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.09.057"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.119.024889"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"372","DOI":"10.2152\/jmi.67.372","article-title":"Successful mechanical thrombectomy for subocclusive thrombus at the origin of lenticulostriate artery","volume":"67","author":"Ohbuchi H","year":"2020","unstructured":"Ohbuchi H, Kanazawa R, Yoshihara T, Takahashi Y, Arai N, Hirota K, Kasuya H. Successful mechanical thrombectomy for subocclusive thrombus at the origin of lenticulostriate artery. J Med Invest. 2020;67:372\u2010374. https:\/\/doi.org\/10.2152\/jmi.67.372","journal-title":"J Med Invest"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.828245","article-title":"Mechanical thrombectomy for M1 subocclusive thrombus with lateral lenticulostriate artery occlusion: a case report and literature review","volume":"13","author":"Yajima H","year":"2022","unstructured":"Yajima H, Koizumi S, Miyawaki S, Saito N. Mechanical thrombectomy for M1 subocclusive thrombus with lateral lenticulostriate artery occlusion: a case report and literature review. Front Neurol. 2022;13:828245. https:\/\/doi.org\/10.3389\/fneur.2022.828245","journal-title":"Front Neurol"}],"container-title":["Stroke: Vascular and Interventional Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/SVIN.124.001367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T11:27:32Z","timestamp":1747654052000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/SVIN.124.001367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1161\/SVIN.124.001367"],"URL":"https:\/\/doi.org\/10.1161\/svin.124.001367","relation":{},"ISSN":["2694-5746"],"issn-type":[{"type":"electronic","value":"2694-5746"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e001367"}}