{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:17:34Z","timestamp":1783693054827,"version":"3.55.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["SVIN"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Pediatric acute ischemic stroke is a rare entity, and mechanical thrombectomy (MT) in this population can be technically challenging. We aim to discuss key technical aspects of pediatric MT and report our experience in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Pediatric patients were identified from our prospectively maintained database of MT patients. Inclusion criteria were pediatric patients\u2019 age &gt;28 days and &lt;18 years undergoing MT for large vessel occlusion at a single center between 2012 and 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Seven patients were included in this case series. Patient age ranged from \u22481 to 17 (10.0\u00b16.2) years. Causes of large vessel occlusion included hypercoagulability disorders, cardiac disorders, and iatrogenic during neurointerventions. Most patients (n=5, 71.4%) had middle cerebral artery or internal carotid artery occlusions. Six patients (85.7%) were successfully treated with MT, achieving modified Thrombolysis in Cerebral Infarction grade 2C or above. Five patients were treated with stent retriever MT and the other 2 patients with aspiration MT alone, with an average of 2.3\u00b11.5 passes total. Five patients (71.4%) made an excellent clinical recovery with a pediatric modified Rankin Scale score \u22642 at last outpatient follow-up (pediatric modified Rankin Scale score, 1.8\u00b11.2). Average follow-up duration was 2.7\u00b12.4 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Recent advancements in catheter technology have facilitated MT in pediatric patients. Pediatric MT appears to be safe and effective for treating cerebral large vessel occlusions; however, technical limitations can arise secondary to small vessel diameters. A technical guide based on patient age and femoral artery diameter is provided.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/svin.125.002180","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T09:00:21Z","timestamp":1781686821000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanical Thrombectomy for Pediatric Acute Ischemic Stroke With Large Vessel Occlusion: Technical Guide and Case Series"],"prefix":"10.1161","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8835-0432","authenticated-orcid":true,"given":"Zachary A.","family":"Sorrentino","sequence":"first","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuyang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6577-4080","authenticated-orcid":true,"given":"Brandon P.","family":"Lucke-Wold","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyas","family":"Sarathy","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2985-7799","authenticated-orcid":true,"given":"Amanda","family":"Stanton","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Hasanpour Segherlou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3202-3949","authenticated-orcid":true,"given":"Hunter","family":"Hutchinson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (Z.A.S., W.Y., B.P.L.-W., D.S., A. Stanton, Z.H.S., H.H., S.A., M.J.K., B.L.H., N.C.), University of Florida College of Medicine, Gainesville."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Stern","sequence":"additional","affiliation":[{"name":"Department of Pediatrics (A. 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