{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:11:10Z","timestamp":1788891070428,"version":"build-2803163510"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["SVIN"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Posterior circulation large-vessel occlusion strokes have significant morbidity and mortality, but patient selection for acute interventions remains understudied. Multiple computed tomography (CT)\u2013based scores exist, including the CT perfusion\u2013based critical area perfusion score (CAPS), CT angiography\u2013based basilar artery treatment management and posterior circulation CT angiography scores, and CT angiography source image or noncontrast CT\u2013based posterior circulation Alberta Stroke Program Early CT Score, but their predictive values for long-term outcomes after thrombectomy have not been directly compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We conducted a retrospective multicenter cohort study of patients with basilar artery occlusions treated with endovascular thrombectomy. Four CT-based scores were assessed: posterior circulation Alberta Stroke Program Early CT Score, basilar artery treatment management score, posterior circulation CT angiography score, and CAPS. The primary outcome of interest for the study was a favorable functional outcome at 3 months (modified Rankin Scale score, 0\u20133). We calculated sensitivity, specificity, positive and negative predictive values, and generated receiver operating characteristic curves measuring area under the curve (AUC), which were compared with nonparametric methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Ninety-eight patients were included for analysis, with an average age of 64.9\u2009\u00b1\u200915.6 years. The median National Institutes of Health Stroke Scale score was 13.5 (interquartile range, 7.0\u201323.0). AUC values were highest for the CAPS (AUC, 0.72 [95% CI, 0.63\u201382]) and lowest for the posterior circulation CT angiography score (AUC, 0.57 [95% CI, 0.45\u20130.68];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.019). There was a trend toward the CAPS outperforming the basilar artery treatment management score (AUC, 0.66 [95% CI, 0.55\u20130.77]) and posterior circulation Alberta Stroke Program Early CT Score (AUC, 0.63 [95% CI, 0.52\u20130.75]) though this was not statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.29 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.23, respectively). CAPS \u22643 demonstrated 100% sensitivity and negative predictive value (95% CI, 92.6\u2013100.0%; 95% CI, 75.7\u2013100.0%, respectively) for good outcome but had low specificity (24.0% [95% CI, 14.3\u201337.4]).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The CT perfusion\u2013based CAPS had the best performance for predicting good functional outcome at 3 months and had high sensitivity and negative predictive values though our finding is limited by the small number of patients who had CAPS &gt;3. The CAPS should be validated in prospective studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/svin.125.002185","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T09:00:16Z","timestamp":1786698016000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Computed Tomography\u2013Based Imaging Scores in Basilar Artery Occlusions: A Comparison of Predictive Abilities for Functional Outcomes"],"prefix":"10.1161","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8455-8201","authenticated-orcid":true,"given":"Ronda","family":"Lun","sequence":"first","affiliation":[{"name":"Vascular Neurology (R.L., P.S., L.C.F., M.M., N.Y., G.W.A.), Stanford Health Care, Palo Alto, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parshva","family":"Shah","sequence":"additional","affiliation":[{"name":"Vascular Neurology (R.L., P.S., L.C.F., M.M., N.Y., G.W.A.), Stanford Health Care, Palo Alto, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8704-1280","authenticated-orcid":true,"given":"Lia Carolina","family":"Franco","sequence":"additional","affiliation":[{"name":"Vascular Neurology (R.L., P.S., L.C.F., M.M., N.Y., G.W.A.), Stanford Health Care, Palo Alto, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6479-1476","authenticated-orcid":true,"given":"Carlo W.","family":"Cereda","sequence":"additional","affiliation":[{"name":"Stroke Center, Neurology, Neurocenter of Southern Switzerland, Ente Ospedaliero Cantonale (EOC), Lugano (C.W.C)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7483-8699","authenticated-orcid":true,"given":"Michael","family":"Mlynash","sequence":"additional","affiliation":[{"name":"Vascular Neurology (R.L., P.S., L.C.F., M.M., N.Y., G.W.A.), Stanford Health Care, Palo Alto, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3206-6656","authenticated-orcid":true,"given":"Nicole","family":"Yuen","sequence":"additional","affiliation":[{"name":"Vascular Neurology (R.L., P.S., L.C.F., M.M., N.Y., G.W.A.), Stanford Health Care, Palo Alto, CA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1498-6638","authenticated-orcid":true,"given":"Abid Y.","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Division of Stroke, University of Kansas Hospital (A.Y.Q.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Hinduja","sequence":"additional","affiliation":[{"name":"Division of Neurology-Stroke, Ohio State University, Columbus (A.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3141-1094","authenticated-orcid":true,"given":"Seena","family":"Dehkharghani","sequence":"additional","affiliation":[{"name":"Department of Radiology (S.D.), Montefiore-Albert Einstein College of Medicine, Bronx, NY."},{"name":"Department of Neurology (S.D.), Montefiore-Albert Einstein College of Medicine, Bronx, NY."},{"name":"Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY (S.D.)."},{"name":"Division of Neurology, New York University Grossman School of Medicine-Langone Health (S.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam E.","family":"Goldman Yassen","sequence":"additional","affiliation":[{"name":"Department of Imaging and Radiological Sciences, Emory School of Medicine, Atlanta, GA (A.E.G.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7725-9019","authenticated-orcid":true,"given":"Kevin Li-Chun","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Radiology, Taipei Medical University Hospital, Taiwan (K.L.-C.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8065-6821","authenticated-orcid":true,"given":"Dan Victor","family":"Giurgiutiu","sequence":"additional","affiliation":[{"name":"Vascular and Interventional Neurology, Wellstar MCG Health, Augusta, GA (D.V.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Carmel, IN (D.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0045-5382","authenticated-orcid":true,"given":"Emmanuel","family":"Carrera","sequence":"additional","affiliation":[{"name":"Department of Neurology, H\u00f4pitaux Universitaires de Gen\u00e8ve, Switzerland (E.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4001-1591","authenticated-orcid":true,"given":"Fana","family":"Alemseged","sequence":"additional","affiliation":[{"name":"Department of Medicine and Neurology, Royal Melbourne Hospital (F.A.), University of Melbourne, Parkville, VIC, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-2020","authenticated-orcid":true,"given":"Tobias D.","family":"Faizy","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology Division, University Medical Center M\u00fcnster, Germany (T.D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8533-7478","authenticated-orcid":true,"given":"Jens","family":"Fiehler","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Germany (J.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7691-8999","authenticated-orcid":true,"given":"Marco","family":"Pileggi","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Switzerland (M.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3632-9433","authenticated-orcid":true,"given":"Bruce","family":"Campbell","sequence":"additional","affiliation":[{"name":"Division of Stroke, Department of Medicine (B.C., C.W.), University of Melbourne, Parkville, VIC, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Wells","sequence":"additional","affiliation":[{"name":"Division of Stroke, Department of Medicine (B.C., C.W.), University of Melbourne, Parkville, VIC, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1055-8000","authenticated-orcid":true,"given":"Jeremy J.","family":"Heit","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology (J.J.H.), Stanford Health Care, Palo Alto, 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