{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:51:17Z","timestamp":1780390277887,"version":"3.54.1"},"reference-count":61,"publisher":"Croatian Society for Medical Biochemistry and Laboratory Medicine","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochem. med. (Online)"],"published-print":{"date-parts":[[2019,6,15]]},"abstract":"<jats:p>A modern diagnostic laboratory offers wide spectrum of coagulation assays utilized in the diagnosis and management of patients with haemostatic disorders, preoperative screening and anticoagulation therapy monitoring. The recent survey conducted among Croatian medical biochemistry and transfusion laboratories showed the existence of different practice policies in particular phases of laboratory process during coagulation testing and highlighted areas that need improvement. Lack of assay standardization together with non-harmonized test results between different measurement methods, can potentially lead to incorrect decisions in patient\u2019s treatment. Consequently, patient safety could be compromised. Therefore, recommended procedures related to preanalytical, analytical and postanalytical phases of prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen and D-dimer testing are provided in this review, aiming to help laboratories to generate accurate and reliable test results.<\/jats:p>","DOI":"10.11613\/bm.2019.020503","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T08:31:19Z","timestamp":1559896279000},"page":"262-283","source":"Crossref","is-referenced-by-count":31,"title":["Croatian Society of Medical Biochemistry and Laboratory Medicine: National recommendations for blood collection, processing, performance and reporting of results for coagulation screening assays prothrombin time, activated partial thromboplastin time"],"prefix":"10.11613","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7383-328X","authenticated-orcid":false,"given":"Ana","family":"Broni\u0107","sequence":"first","affiliation":[{"name":"Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8327-9913","authenticated-orcid":false,"given":"Desiree","family":"Coen Herak","sequence":"additional","affiliation":[{"name":"Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Margeti\u0107","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2592-3819","authenticated-orcid":false,"given":"Marija","family":"Mili\u0107","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Diagnostics, Osijek University Hospital, Osijek, Croatia; Faculty of Medicine, University of Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4885","published-online":{"date-parts":[[2019,4,14]]},"reference":[{"key":"key20190607043112_r1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1152\/physrev.00016.2011","article-title":"New Fundamentals in Hemostasis.","volume":"93","author":"Versteeg","year":"2013","journal-title":"Physiol Rev"},{"key":"key20190607043112_r2","first-page":"184","article-title":"Quality in coagulation and haemostasis testing.","volume-title":"Biochem Med (Zagreb)","author":"Bonar","year":"2010"},{"key":"key20190607043112_r3","unstructured":"Harris NS, Bazydlo LAL, Winter WE. 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