{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T07:13:58Z","timestamp":1690182838142},"reference-count":15,"publisher":"Croatian Society for Medical Biochemistry and Laboratory Medicine","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochem. med. (Online)"],"published-print":{"date-parts":[[2020,10,15]]},"abstract":"<jats:p>Laboratory investigations of hypercalcemia involve testing of various biochemical parameters such as parathyroid hormone (PTH), 25-(OH) Vitamin D (25-(OH) VitD), 1,25-(OH)2 Vitamin D3 (calcitriol) and PTH related peptide (PTHrp). We herein present an atypical case of severe hypercalcemia in a patient with rheumatoid arthritis who has been treated for years by various biological\ndisease-modifying antirheumatic drugs (DMARDs) and suddenly presented with general state alteration, oedema and ulceration of her right ankle. We illustrate how tuberculosis (TB) can cause high calcitriol concentration and subsequently lead to potentially severe hypercalcemia. Moreover, we highlight the importance of TB testing and follow-up in patients treated with biological DMARDs.<\/jats:p>","DOI":"10.11613\/bm.2020.030801","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T07:44:37Z","timestamp":1596181477000},"page":"471-474","source":"Crossref","is-referenced-by-count":3,"title":["A rare case of tuberculosis-induced hypercalcemia"],"prefix":"10.11613","volume":"30","author":[{"given":"Loris","family":"Wauthier","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Theunssens","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Durez","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium; P\u00f4le de Pathologies rhumatismales, Institut de Recherche Expe\u0301rimentale et Clinique, Universite\u0301 Catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Fill\u00e9e","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Maisin","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Gruson","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Cliniques Universitaires St-Luc and Universit\u00e9 Catholique de Louvain, Brussels, Belgium; P\u00f4le de recherche en Endocrinologie, Diab\u00e8te et Nutrition, Institut de Recherche Exp\u00e9rimentale et Clinique, Cliniques Universitai"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4885","published-online":{"date-parts":[[2020,10,12]]},"reference":[{"key":"key20200731034432_r1","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1002\/jbmr.5650061413","article-title":"Differential diagnosis of hypercalcemia.","volume":"6","author":"Lafferty","year":"1991","journal-title":"J Bone Miner Res"},{"key":"key20200731034432_r2","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.clinbiochem.2012.04.025","article-title":"Investigation of 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