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Unexpectedly, the samples collected from the two different sources showed contrasting results, with the presence of unusual macrophage-like cells in the samples obtained from CVC. It was later found that the CVC was displaced into the pleural space. This case report shows how the sampling process can sometimes influence test results and how it can help clinicians identify clinical conditions that have not yet manifested.<\/jats:p>","DOI":"10.11613\/bm.2022.031001","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T06:28:34Z","timestamp":1663914514000},"page":"441-445","source":"Crossref","is-referenced-by-count":1,"title":["A case of discrepant laboratory results in samples obtained from a central venous catheter and peripheral veins: when solving a pre-analytical mystery could improve patient care"],"prefix":"10.11613","volume":"32","author":[{"given":"Duilio","family":"Brugnoni","sequence":"first","affiliation":[{"name":"Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Portesi","sequence":"additional","affiliation":[{"name":"Molecular and Translational Medicine Department, University of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Serana","sequence":"additional","affiliation":[{"name":"Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moira","family":"Micheletti","sequence":"additional","affiliation":[{"name":"Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattia","family":"Carini","sequence":"additional","affiliation":[{"name":"Molecular and Translational Medicine Department, University of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Martellosio","sequence":"additional","affiliation":[{"name":"Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Caravaggi","sequence":"additional","affiliation":[{"name":"Molecular and Translational Medicine Department, University of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Biasiotto","sequence":"additional","affiliation":[{"name":"Molecular and Translational Medicine Department, University of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Marini","sequence":"additional","affiliation":[{"name":"Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4885","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"key20220923022825_r1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1515\/CCLM.2006.073","article-title":"Preanalytical variability: the dark side of the moon in laboratory testing.","volume":"44","author":"Lippi","year":"2006","journal-title":"Clin Chem Lab Med"},{"key":"key20220923022825_r2","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1515\/CCLM.2006.123","article-title":"Errors in Clinical Laboratories or errors in laboratory medicine?","volume":"44","author":"Plebani","year":"2006","journal-title":"Clin Chem Lab Med"},{"key":"key20220923022825_r3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1515\/dx-2018-0018","article-title":"Blood sample quality.","volume":"6","author":"Lippi","year":"2019","journal-title":"Diagnosis (Berl)"},{"key":"key20220923022825_r4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1258\/acb.2009.009222","article-title":"The detection and prevention of errors in laboratory medicine.","volume":"47","author":"Plebani","year":"2010","journal-title":"Ann Clin Biochem"},{"key":"key20220923022825_r5","unstructured":"WHO World Health Organization (WHO). 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