{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:31:08Z","timestamp":1791419468701,"version":"4.3.3"},"reference-count":65,"publisher":"MIT Press","issue":"11","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>How does motivation interact with cognitive control during challenging behavioral conditions? Here, we investigated the interactions between motivation and cognition during a response conflict task and tested a specific model of the effect of reward on cognitive processing. Behaviorally, participants exhibited reduced conflict during the reward versus no-reward condition. Brain imaging results revealed that a group of subcortical and fronto-parietal regions was robustly influenced by reward at cue processing and, importantly, that cue-related responses in fronto-parietal attentional regions were predictive of reduced conflict-related signals in the medial pFC (MPFC)\/ACC during the upcoming target phase. Path analysis revealed that the relationship between cue responses in the right intraparietal sulcus (IPS) and interference-related responses in the MPFC during the subsequent target phase was mediated via signals in the left fusiform gyrus, which we linked to distractor-related processing. Finally, reward increased functional connectivity between the right IPS and both bilateral putamen and bilateral nucleus accumbens during the cue phase, a relationship that covaried with across-individual sensitivity to reward in the case of the right nucleus accumbens. Taken together, our findings are consistent with a model in which motivationally salient cues are employed to upregulate top\u2013down control processes that bias the selection of visual information, thereby leading to more efficient stimulus processing during conflict conditions.<\/jats:p>","DOI":"10.1162\/jocn_a_00011","type":"journal-article","created":{"date-parts":[[2011,3,31]],"date-time":"2011-03-31T09:27:41Z","timestamp":1301563661000},"page":"3419-3432","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":316,"title":["Reward Reduces Conflict by Enhancing Attentional Control and Biasing Visual Cortical Processing"],"prefix":"10.1162","volume":"23","author":[{"given":"Srikanth","family":"Padmala","sequence":"first","affiliation":[{"name":"1Indiana University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz","family":"Pessoa","sequence":"additional","affiliation":[{"name":"2University 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