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Analysis using a model-based fMRI method revealed that activity in the right lateral OFC (lOFC) of responders increased as a function of negative decision bias, indicating a greater likelihood of rejecting otherwise fair offers, possibly because of the facial trustworthiness of proposers. In addition, lOFC showed changes in functional connectivity strength with amygdala and insula as a function of decision bias, and individual differences in the strengths of connectivities between lOFC and bilateral insula were also found to predict the likelihood of responders to reject offers from untrustworthy-looking proposers. The present findings emphasize that the lOFC plays a pivotal role in integrating signals related to facial impression and creating signal biasing decisions during social interactions.<\/jats:p>","DOI":"10.1162\/jocn_a_00136","type":"journal-article","created":{"date-parts":[[2011,9,26]],"date-time":"2011-09-26T14:44:21Z","timestamp":1317048261000},"page":"428-439","update-policy":"http:\/\/dx.doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":20,"title":["Lateral OFC Activity Predicts Decision Bias due to First Impressions during Ultimatum Games"],"prefix":"10.1162","volume":"24","author":[{"given":"Hackjin","family":"Kim","sequence":"first","affiliation":[]},{"given":"Min-Jo","family":"Choi","sequence":"additional","affiliation":[]},{"given":"In-Ji","family":"Jang","sequence":"additional","affiliation":[]}],"member":"281","published-online":{"date-parts":[[2012,2,1]]},"reference":[{"key":"2021072913172733500_R1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/30982","article-title":"The human amygdala in social judgment.","volume":"393","author":"Adolphs","year":"1998","journal-title":"Nature"},{"key":"2021072913172733500_R2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.joep.2007.07.008","article-title":"Beauty, gender, and stereotypes: Evidence from laboratory experiments.","volume":"29","author":"Andreoni","year":"2008","journal-title":"Journal of Economic Psychology"},{"key":"2021072913172733500_R3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0165-0173(96)00011-2","article-title":"Circuitry and functional aspects of the insular lobe in primates including humans.","volume":"22","author":"Augustine","year":"1996","journal-title":"Brain Research, Brain Research Reviews"},{"key":"2021072913172733500_R4","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1523\/JNEUROSCI.2744-10.2011","article-title":"Deep and superficial amygdala nuclei projections revealed in vivo by probabilistic tractography.","volume":"31","author":"Bach","year":"2011","journal-title":"Journal of Neuroscience"},{"key":"2021072913172733500_R5","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.neuron.2008.04.009","article-title":"Oxytocin shapes the neural circuitry of trust and trust adaptation in humans.","volume":"58","author":"Baumgartner","year":"2008","journal-title":"Neuron"},{"key":"2021072913172733500_R6","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1523\/JNEUROSCI.20-11-04311.2000","article-title":"Control of response selection by reinforcer value requires interaction of amygdala and orbital prefrontal cortex.","volume":"20","author":"Baxter","year":"2000","journal-title":"Journal of Neuroscience"},{"key":"2021072913172733500_R7","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/cercor\/10.3.295","article-title":"Emotion, decision making and the orbitofrontal cortex.","volume":"10","author":"Bechara","year":"2000","journal-title":"Cerebral Cortex"},{"key":"2021072913172733500_R8","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/cercor\/10.3.205","article-title":"The mysterious orbitofrontal cortex. 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