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Before picture encoding, participants were subjected either to the Socially Evaluated Cold Pressor Test (SECPT) or to a warm water control procedure. The exposure to the SECPT resulted in increased subjective and autonomic (heart rate and blood pressure) stress responses relative to the control condition. Viewing of unpleasant relative to neutral pictures evoked enhanced late positive potentials (LPPs) over centro-parietal scalp sites around 400 msec after picture onset. Prior exposure to acute stress selectively increased the LPPs for unpleasant pictures. Moreover, the LPP magnitude for unpleasant pictures following the SECPT was positively associated with incidental free recall performance 24 hr later. The present results suggest that acute stress sensitizes the brain for increased processing of cues in the environment, particularly priming the processing of unpleasant cues. This increased processing is related to later long-term memory performance.<\/jats:p>","DOI":"10.1162\/jocn_a_00174","type":"journal-article","created":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T14:33:11Z","timestamp":1324391591000},"page":"1511-1518","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":58,"title":["Stress Sensitizes the Brain: Increased Processing of Unpleasant Pictures after Exposure to Acute Stress"],"prefix":"10.1162","volume":"24","author":[{"given":"Mathias","family":"Weymar","sequence":"first","affiliation":[{"name":"1University of Greifswald"},{"name":"2University of Florida"}]},{"given":"Lars","family":"Schwabe","sequence":"additional","affiliation":[{"name":"3Ruhr-University Bochum"}]},{"given":"Andreas","family":"L\u00f6w","sequence":"additional","affiliation":[{"name":"1University of Greifswald"}]},{"given":"Alfons 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