{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T13:25:55Z","timestamp":1771075555695,"version":"3.50.1"},"reference-count":42,"publisher":"MIT Press - Journals","issue":"8","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Moral sentiment has been hypothesized to reflect evolved adaptations to social living. If so, individual differences in moral values may relate to regional variation in brain structure. We tested this hypothesis in a sample of 70 young, healthy adults examining whether differences on two major dimensions of moral values were significantly associated with regional gray matter volume. The two clusters of moral values assessed were \u201cindividualizing\u201d (values of harm\/care and fairness) and \u201cbinding\u201d (deference to authority, in-group loyalty, and purity\/sanctity). Individualizing was positively associated with left dorsomedial pFC volume and negatively associated with bilateral precuneus volume. For binding, a significant positive association was found for bilateral subcallosal gyrus and a trend to significance for the left anterior insula volume. These findings demonstrate that variation in moral sentiment reflects individual differences in brain structure and suggest a biological basis for moral sentiment, distributed across multiple brain regions.<\/jats:p>","DOI":"10.1162\/jocn_a_00239","type":"journal-article","created":{"date-parts":[[2012,5,9]],"date-time":"2012-05-09T16:31:27Z","timestamp":1336581087000},"page":"1657-1663","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":51,"title":["Moral Values Are Associated with Individual Differences in Regional Brain Volume"],"prefix":"10.1162","volume":"24","author":[{"given":"Gary J.","family":"Lewis","sequence":"first","affiliation":[{"name":"1University of California, Santa Barbara"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Kanai","sequence":"additional","affiliation":[{"name":"2University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy C.","family":"Bates","sequence":"additional","affiliation":[{"name":"3University of Edinburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraint","family":"Rees","sequence":"additional","affiliation":[{"name":"2University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","published-online":{"date-parts":[[2012,8,1]]},"reference":[{"key":"2021072913223914500_R1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/nrn1884","article-title":"Meeting of minds: The medial frontal cortex and social cognition.","volume":"7","author":"Amodio","year":"2006","journal-title":"Nature Reviews Neuroscience"},{"key":"2021072913223914500_R2","first-page":"45","article-title":"Social cognitive theory of moral thought and action.","volume-title":"Handbook of moral behavior and development: Theory, research, and applications","author":"Bandura","year":"1991"},{"key":"2021072913223914500_R3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.tics.2007.07.003","article-title":"The amygdala and ventromedial prefrontal cortex in morality and psychopathy.","volume":"11","author":"Blair","year":"2007","journal-title":"Trends in Cognitive Sciences"},{"key":"2021072913223914500_R4","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1093\/cercor\/bhl161","article-title":"Empathy for pain and touch in the human somatosensory cortex.","volume":"17","author":"Bufalari","year":"2007","journal-title":"Cerebral Cortex"},{"key":"2021072913223914500_R5","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1038\/80586","article-title":"Impaired recognition and experience of disgust following brain injury.","volume":"3","author":"Calder","year":"2000","journal-title":"Nature Neuroscience"},{"key":"2021072913223914500_R6","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1002\/hbm.20671","article-title":"Are there theory of mind regions in the brain? 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