{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:43:43Z","timestamp":1775922223892,"version":"3.50.1"},"reference-count":61,"publisher":"MIT Press - Journals","issue":"10","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The human visual system converts identically sized retinal stimuli into different-sized perceptions. For instance, the M\u00fcller-Lyer illusion alters the perceived length of a line via arrows attached to its end. The strength of this illusion can be expressed as the difference between physical and perceived line length. Accordingly, illusion strength reflects how strong a representation is transformed along its way from a retinal image up to a conscious percept. In this study, we investigated changes of effective connectivity between brain areas supporting these transformation processes to further elucidate the neural underpinnings of optical illusions. The strength of the M\u00fcller-Lyer illusion was parametrically modulated while participants performed either a spatial or a luminance task. Lateral occipital cortex and right superior parietal cortex were found to be associated with illusion strength. Dynamic causal modeling was employed to investigate putative interactions between ventral and dorsal visual streams. Bayesian model selection indicated that a model that involved bidirectional connections between dorsal and ventral stream areas most accurately accounted for the underlying network dynamics. Connections within this network were partially modulated by illusion strength. The data further suggest that the two areas subserve differential roles: Whereas lateral occipital cortex seems to be directly related to size transformation processes, activation in right superior parietal cortex may reflect subsequent levels of processing, including task-related supervisory functions. Furthermore, the data demonstrate that the observer's top\u2013down settings modulate the interactions between lateral occipital and superior parietal regions and thereby influence the effect of illusion strength.<\/jats:p>","DOI":"10.1162\/jocn_a_00258","type":"journal-article","created":{"date-parts":[[2012,6,21]],"date-time":"2012-06-21T22:39:24Z","timestamp":1340318364000},"page":"2015-2029","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":36,"title":["Ventral and Dorsal Stream Interactions during the Perception of the M\u00fcller-Lyer Illusion: Evidence Derived from fMRI and Dynamic Causal Modeling"],"prefix":"10.1162","volume":"24","author":[{"given":"Thorsten","family":"Plewan","sequence":"first","affiliation":[{"name":"1Research Centre J\u00fclich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Weidner","sequence":"additional","affiliation":[{"name":"1Research Centre J\u00fclich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon B.","family":"Eickhoff","sequence":"additional","affiliation":[{"name":"1Research Centre J\u00fclich"},{"name":"2Heinrich-Heine University, D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gereon R.","family":"Fink","sequence":"additional","affiliation":[{"name":"1Research Centre J\u00fclich"},{"name":"3Cologne University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","published-online":{"date-parts":[[2012,10,1]]},"reference":[{"key":"2021072913155704900_R1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.neuroimage.2005.02.018","article-title":"Unified segmentation.","volume":"26","author":"Ashburner","year":"2005","journal-title":"Neuroimage"},{"key":"2021072913155704900_R2","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3758\/BF03194718","article-title":"Size scaling: Retinal or environmental frame of reference?","volume":"64","author":"Bennett","year":"2002","journal-title":"Perception & Psychophysics"},{"key":"2021072913155704900_R3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1006\/brcg.1998.1003","article-title":"Perceptual and response bias in unilateral neglect: Two modified versions of the Milner landmark task.","volume":"37","author":"Bisiach","year":"1998","journal-title":"Brain and Cognition"},{"key":"2021072913155704900_R4","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1046\/j.1460-9568.2003.02679.x","article-title":"Illusory contours and specific regions of human extrastriate cortex: Evidence from rTMS.","volume":"17","author":"Brighina","year":"2003","journal-title":"The European Journal of Neuroscience"},{"key":"2021072913155704900_R5","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.neubiorev.2007.08.006","article-title":"Visually guided pointing, the M\u00fcller-Lyer illusion, and the functional interpretation of the dorsal-ventral split: Conclusions from 33 independent studies.","volume":"32","author":"Bruno","year":"2008","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"2021072913155704900_R6","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/j.neuropsychologia.2008.10.031","article-title":"When is grasping affected by the M\u00fcller-Lyer illusion? 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