{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:06:56Z","timestamp":1775790416208,"version":"3.50.1"},"reference-count":68,"publisher":"MIT Press - Journals","issue":"7","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Action selection often requires the transformation of visual information into motor plans. Preventing premature responses may entail the suppression of visual input and\/or of prepared muscle activity. This study examined how the quality of visual information affects frontobasal ganglia (BG) routes associated with response selection and inhibition. Human fMRI data were collected from a stop task with visually degraded or intact face stimuli. During go trials, degraded spatial frequency information reduced the speed of information accumulation and response cautiousness. Effective connectivity analysis of the fMRI data showed action selection to emerge through the classic direct and indirect BG pathways, with inputs deriving form both prefrontal and visual regions. When stimuli were degraded, visual and prefrontal regions processing the stimulus information increased connectivity strengths toward BG, whereas regions evaluating visual scene content or response strategies reduced connectivity toward BG. Response inhibition during stop trials recruited the indirect and hyperdirect BG pathways, with input from visual and prefrontal regions. Importantly, when stimuli were nondegraded and processed fast, the optimal stop model contained additional connections from prefrontal to visual cortex. Individual differences analysis revealed that stronger prefrontal-to-visual connectivity covaried with faster inhibition times. Therefore, prefrontal-to-visual cortex connections appear to suppress the fast flow of visual input for the go task, such that the inhibition process can finish before the selection process. These results indicate response selection and inhibition within the BG to emerge through the interplay of top\u2013down adjustments from prefrontal and bottom\u2013up input from sensory cortex.<\/jats:p>","DOI":"10.1162\/jocn_a_00792","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T18:31:40Z","timestamp":1422988300000},"page":"1344-1359","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":28,"title":["Visual Information Shapes the Dynamics of Corticobasal Ganglia Pathways during Response Selection and Inhibition"],"prefix":"10.1162","volume":"27","author":[{"given":"Sara","family":"Jahfari","sequence":"first","affiliation":[{"name":"1VU University Amsterdam"}]},{"given":"Lourens","family":"Waldorp","sequence":"additional","affiliation":[{"name":"2University of Amsterdam"}]},{"given":"K. 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