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A group of 30 relatively older participants (range = 39\u201379 years of age) underwent extensive neuropsychological testing, combined with diffusion-weighted magnetic resonance imaging to reconstruct individual structural brain networks. Rich club connectivity was found to be associated with general cognitive performance. More specifically, assessing the relationship between the rich club and performance in two specific cognitive domains, we found rich club connectivity to be differentially associated with attention\/executive functions\u2014known to rely on the integration of distributed brain areas\u2014rather than with visuospatial\/visuoperceptual functions, which have a more constrained neuroanatomical substrate. Our findings thus provide first empirical evidence of a relevant role played by the rich club in cognitive processes.<\/jats:p>","DOI":"10.1162\/jocn_a_00821","type":"journal-article","created":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T16:55:09Z","timestamp":1430844909000},"page":"1801-1810","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":55,"title":["Rich Club Organization and Cognitive Performance in Healthy Older Participants"],"prefix":"10.1162","volume":"27","author":[{"given":"Hugo C.","family":"Baggio","sequence":"first","affiliation":[{"name":"1University of Barcelona"},{"name":"2CIBERNED, Barcelona"}]},{"given":"Barbara","family":"Segura","sequence":"additional","affiliation":[{"name":"1University of Barcelona"}]},{"given":"Carme","family":"Junque","sequence":"additional","affiliation":[{"name":"1University of Barcelona"},{"name":"2CIBERNED, Barcelona"}]},{"given":"Marcel A.","family":"de Reus","sequence":"additional","affiliation":[{"name":"3University Medical Center Utrecht"}]},{"given":"Roser","family":"Sala-Llonch","sequence":"additional","affiliation":[{"name":"1University of Barcelona"}]},{"given":"Martijn P.","family":"Van den Heuvel","sequence":"additional","affiliation":[{"name":"3University Medical Center Utrecht"}]}],"member":"281","published-online":{"date-parts":[[2015,9,1]]},"reference":[{"key":"2021073000533561700_R1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1212\/WNL.0b013e31829a33f8","article-title":"Brain network connectivity assessed using graph theory in frontotemporal dementia","volume":"81","author":"Agosta","year":"2013","journal-title":"Neurology"},{"key":"2021073000533561700_R2","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.neuroimage.2013.06.053","article-title":"Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders","volume":"83","author":"Arenaza-Urquijo","year":"2013","journal-title":"Neuroimage"},{"key":"2021073000533561700_R3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1467-9868.2010.00746.x","article-title":"Discovering the false discovery rate","volume":"72","author":"Benjamini","year":"2010","journal-title":"Journal of the Royal Statistical Society: Series B, Statistical Methodology"},{"key":"2021073000533561700_R4","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/0165-0173(94)00016-I","article-title":"Large-scale cortical networks and cognition","volume":"20","author":"Bressler","year":"1995","journal-title":"Brain Research. 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