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Using fMRI, we examined whether these two types of information can activate the motor system in the absence of specific motor-semantic content by manipulating the existence of a sublexical cue, called the hand radical, which strongly indicates the semantic feature \u201chand-related\u201d and grammatical class \u201cverb.\u201d Although hand radical characters referring to specific manual actions evoked stronger activation in the premotor cortex than the control characters, hand radical pseudocharacters did not evoke specific activation within the motor system. These results indicated that activation of the premotor cortex during word reading relies on the access of specific action concepts.<\/jats:p>","DOI":"10.1162\/jocn_a_00852","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T14:08:41Z","timestamp":1438265321000},"page":"2051-2062","update-policy":"http:\/\/dx.doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":9,"title":["Premotor Cortex Activation Elicited during Word Comprehension Relies on Access of Specific Action Concepts"],"prefix":"10.1162","volume":"27","author":[{"given":"Nan","family":"Lin","sequence":"first","affiliation":[{"name":"1Chinese Academy of Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoying","family":"Wang","sequence":"additional","affiliation":[{"name":"2Beijing Normal University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhao","sequence":"additional","affiliation":[{"name":"2Beijing Normal University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanping","family":"Liu","sequence":"additional","affiliation":[{"name":"1Chinese Academy of Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingshan","family":"Li","sequence":"additional","affiliation":[{"name":"1Chinese Academy of Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanchao","family":"Bi","sequence":"additional","affiliation":[{"name":"2Beijing Normal University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","published-online":{"date-parts":[[2015,10,1]]},"reference":[{"key":"2021073000523420000_R1","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1016\/j.cub.2006.07.060","article-title":"Congruent embodied representations for visually presented actions and linguistic phrases describing actions","volume":"16","author":"Aziz-Zadeh","year":"2006","journal-title":"Current Biology"},{"key":"2021073000523420000_R2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1146\/annurev.psych.59.103006.093639","article-title":"Grounded cognition","volume":"59","author":"Barsalou","year":"2008","journal-title":"Annual Review of Psychology"},{"key":"2021073000523420000_R3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.neuropsychologia.2014.06.025","article-title":"Representing tools as hand movements: Early and somatotopic visuomotor transformations","volume":"61","author":"Bartoli","year":"2014","journal-title":"Neuropsychologia"},{"key":"2021073000523420000_R4","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1162\/0898929054021102","article-title":"Distinct brain systems for processing concrete and abstract concepts","volume":"17","author":"Binder","year":"2005","journal-title":"Journal of Cognitive Neuroscience"},{"key":"2021073000523420000_R5","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/hbm.20124","article-title":"Cross-cultural effect on the brain revisited: Universal structures plus writing system variation","volume":"25","author":"Bolger","year":"2005","journal-title":"Human Brain Mapping"},{"key":"2021073000523420000_R6","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1460-9568.2001.01385.x","article-title":"Action observation activates premotor and parietal areas in a somatotopic manner: An fMRI study","volume":"13","author":"Buccino","year":"2001","journal-title":"European Journal of Neuroscience"},{"key":"2021073000523420000_R7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-neuro-071013-013950","article-title":"Embodied cognition and mirror neurons: A critical assessment","volume":"37","author":"Caramazza","year":"2014","journal-title":"Annual Review of Neuroscience"},{"key":"2021073000523420000_R8","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jneuroling.2012.08.001","article-title":"Reading the reading brain: A new meta-analysis of functional imaging data on reading","volume":"26","author":"Cattinelli","year":"2013","journal-title":"Journal of Neurolinguistics"},{"key":"2021073000523420000_R9","unstructured":"Cheng, C. 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