{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:20:35Z","timestamp":1777378835730,"version":"3.51.4"},"reference-count":66,"publisher":"MIT Press - Journals","issue":"2","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Surprising events may be relevant or irrelevant for behavior, requiring either flexible adjustment or stabilization of our model of the world and according response strategies. Cognitive flexibility and stability in response to environmental demands have been described as separable cognitive states, associated with activity of striatal and lateral prefrontal regions, respectively. It so far remains unclear, however, whether these two states act in an antagonistic fashion and which neural mechanisms mediate the selection of respective responses, on the one hand, and a transition between these states, on the other. In this study, we tested whether the functional dichotomy between striatal and prefrontal activity applies for the separate functions of updating (in response to changes in the environment, i.e., switches) and shielding (in response to chance occurrences of events violating expectations, i.e., drifts) of current predictions. We measured brain activity using fMRI while 20 healthy participants performed a task that required to serially predict upcoming items. Switches between predictable sequences had to be indicated via button press while sequence omissions (drifts) had to be ignored. We further varied the probability of switches and drifts to assess the neural network supporting the transition between flexible and stable cognitive states as a function of recent performance history in response to environmental demands. Flexible switching between models was associated with activation in medial pFC (BA 9 and BA 10), whereas stable maintenance of the internal model corresponded to activation in the lateral pFC (BA 6 and inferior frontal gyrus). Our findings extend previous studies on the interplay of flexibility and stability, suggesting that different prefrontal regions are activated by different types of prediction errors, dependent on their behavioral requirements. Furthermore, we found that striatal activation in response to switches and drifts was modulated by participants' successful behavior toward these events, suggesting the striatum to be responsible for response selections following unpredicted stimuli. Finally, we observed that the dopaminergic midbrain modulates the transition between different cognitive states, thresholded by participants' individual performance history in response to temporal environmental demands.<\/jats:p>","DOI":"10.1162\/jocn_a_01040","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T15:46:58Z","timestamp":1473868018000},"page":"298-309","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":21,"title":["Frontostriatal Contribution to the Interplay of Flexibility and Stability in Serial Prediction"],"prefix":"10.1162","volume":"29","author":[{"given":"Ima","family":"Trempler","sequence":"first","affiliation":[{"name":"1Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany"},{"name":"2University Hospital Cologne"},{"name":"3Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of M\u00fcnster, Germany"}]},{"given":"Anne-Marike","family":"Schiffer","sequence":"additional","affiliation":[{"name":"4University of Oxford"},{"name":"5Brunel University, Uxbridge, United Kingdom"}]},{"given":"Nadiya","family":"El-Sourani","sequence":"additional","affiliation":[{"name":"1Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany"},{"name":"2University Hospital Cologne"}]},{"given":"Christiane","family":"Ahlheim","sequence":"additional","affiliation":[{"name":"1Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany"},{"name":"3Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of M\u00fcnster, Germany"}]},{"given":"Gereon R.","family":"Fink","sequence":"additional","affiliation":[{"name":"2University Hospital Cologne"},{"name":"6Research Centre J\u00fclich"}]},{"given":"Ricarda I.","family":"Schubotz","sequence":"additional","affiliation":[{"name":"1Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany"},{"name":"2University Hospital Cologne"},{"name":"3Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of M\u00fcnster, Germany"}]}],"member":"281","published-online":{"date-parts":[[2017,2,1]]},"reference":[{"key":"2021073021062488200_R1","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1162\/jocn_a_00286","article-title":"Prefrontal cortical mechanisms underlying individual differences in cognitive flexibility and stability","volume":"24","author":"Armbruster","year":"2012","journal-title":"Journal of Cognitive Neuroscience"},{"key":"2021073021062488200_R2","volume-title":"Working memory","author":"Baddeley","year":"1986"},{"key":"2021073021062488200_R3","doi-asserted-by":"crossref","first-page":"19878","DOI":"10.1073\/pnas.1216902109","article-title":"Opening the gate to working memory","volume":"109","author":"Badre","year":"2012","journal-title":"Proceedings of the National Academy of Sciences, U.S.A."},{"key":"2021073021062488200_R4","first-page":"14","article-title":"Reducing bias and inefficiency in the selection algorithm","volume-title":"Proceedings of the Second International Conference on Genetic Algorithms and their Application","author":"Baker","year":"1987"},{"key":"2021073021062488200_R5","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3389\/fnbeh.2010.00170","article-title":"Tonic dopamine modulates exploitation of reward learning","volume":"4","author":"Beeler","year":"2010","journal-title":"Frontiers in Behavioral Neuroscience"},{"key":"2021073021062488200_R6","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/nn1954","article-title":"Learning the value of information in an uncertain world","volume":"10","author":"Behrens","year":"2007","journal-title":"Nature Neuroscience"},{"key":"2021073021062488200_R7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.neuroimage.2007.04.042","article-title":"A component based noise correction method (CompCor) for BOLD and perfusion based fMRI","volume":"37","author":"Behzadi","year":"2007","journal-title":"Neuroimage"},{"key":"2021073021062488200_R8","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1038\/sj.npp.1300542","article-title":"The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes","volume":"29","author":"Bilder","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"2021073021062488200_R9","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cobeha.2014.08.001","article-title":"Multiple gates on working memory","volume":"1","author":"Chatham","year":"2015","journal-title":"Current Opinion in Behavioral Sciences"},{"key":"2021073021062488200_R10","doi-asserted-by":"crossref","first-page":"4805","DOI":"10.1002\/hbm.22513","article-title":"Surprise beyond prediction error","volume":"35","author":"Chumbley","year":"2014","journal-title":"Human Brain Mapping"},{"key":"2021073021062488200_R11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1017\/S0140525X12000477","article-title":"Whatever next? Predictive brains, situated agents, and the future of cognitive science","volume":"36","author":"Clark","year":"2013","journal-title":"Behavioral and Brain Sciences"},{"key":"2021073021062488200_R12","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0959-4388(02)00314-8","article-title":"Computational perspectives on dopamine function in prefrontal cortex","volume":"12","author":"Cohen","year":"2002","journal-title":"Current Opinion in Neurobiology"},{"key":"2021073021062488200_R13","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.conb.2011.04.002","article-title":"Dopaminergic control of the striatum for high-level cognition","volume":"21","author":"Cools","year":"2011","journal-title":"Current Opinion in Neurobiology"},{"key":"2021073021062488200_R14","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1016\/j.biopsych.2011.03.028","article-title":"Inverted-U-shaped dopamine actions on human working memory and cognitive control","volume":"69","author":"Cools","year":"2011","journal-title":"Biological Psychiatry"},{"key":"2021073021062488200_R15","doi-asserted-by":"crossref","first-page":"5506","DOI":"10.1523\/JNEUROSCI.0601-07.2007","article-title":"Impulsive personality predicts dopamine-dependent changes in frontostriatal activity during component processes of working memory","volume":"27","author":"Cools","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"2021073021062488200_R16","first-page":"877","article-title":"Prediction error during retrospective revaluation of causal associations in humans: fMRI evidence in favor of an associative model of learning","volume":"44","author":"Corlett","year":"2004","journal-title":"Neuron"},{"key":"2021073021062488200_R17","doi-asserted-by":"crossref","first-page":"19900","DOI":"10.1073\/pnas.1116727109","article-title":"Role of prefrontal cortex and the midbrain dopamine system in working memory updating","volume":"109","author":"D'Ardenne","year":"2012","journal-title":"Proceedings of the National Academy of Sciences, U.S.A."},{"key":"2021073021062488200_R18","doi-asserted-by":"crossref","first-page":"3210","DOI":"10.1523\/JNEUROSCI.4458-09.2010","article-title":"Striatal prediction error modulates cortical coupling","volume":"30","author":"den Ouden","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"2021073021062488200_R19","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1098\/rstb.2007.2086","article-title":"From cognitive to neural models of working memory","volume":"362","author":"D'Esposito","year":"2007","journal-title":"Philosophical Transactions of the Royal Society of London, Series B, Biological Sciences"},{"key":"2021073021062488200_R20","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1146\/annurev-psych-010814-015031","article-title":"The cognitive neuroscience of working memory","volume":"66","author":"D'Esposito","year":"2015","journal-title":"Annual Review of Psychology"},{"key":"2021073021062488200_R21","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/1745691615596990","article-title":"Combining reaction time and accuracy: The relationship between working memory capacity and task switching as a case example","volume":"11","author":"Draheim","year":"2016","journal-title":"Perspectives on Psychological Science"},{"key":"2021073021062488200_R22","first-page":"343","article-title":"How positive affect modulates cognitive control: Reduced perseveration at the cost of increased distractibility","volume":"30","author":"Dreisbach","year":"2004","journal-title":"Journal of Experimental Psychology: Learning, Memory, and Cognition"},{"key":"2021073021062488200_R23","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.biopsych.2008.05.015","article-title":"The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia","volume":"64","author":"Durstewitz","year":"2008","journal-title":"Biological Psychiatry"},{"key":"2021073021062488200_R24","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1038\/81460","article-title":"Neurocomputational models of working memory","volume":"3","author":"Durstewitz","year":"2000","journal-title":"Nature Neuroscience"},{"key":"2021073021062488200_R25","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.neuroimage.2014.10.034","article-title":"The effect of rehearsal rate and memory load on verbal working memory","volume":"105","author":"Fegen","year":"2015","journal-title":"Neuroimage"},{"key":"2021073021062488200_R26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3758\/CABN.1.2.137","article-title":"Interactions between the frontal cortex and basal ganglia in working memory: A computational model","volume":"1","author":"Frank","year":"2001","journal-title":"Cognitive, Affective, and Behavioral Neuroscience"},{"key":"2021073021062488200_R27","doi-asserted-by":"crossref","first-page":"e6421","DOI":"10.1371\/journal.pone.0006421","article-title":"Reinforcement learning or active inference?","volume":"4","author":"Friston","year":"2009","journal-title":"PLoS One"},{"key":"2021073021062488200_R28","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/hbm.460020402","article-title":"Statistical parametric maps in functional imaging: A general linear approach","volume":"2","author":"Friston","year":"1995","journal-title":"Human Brain Mapping"},{"key":"2021073021062488200_R29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1467-9280.2008.02042.x","article-title":"Conflict-triggered goal-shielding attenuates background-monitoring for prospective memory cues","volume":"19","author":"Goschke","year":"2008","journal-title":"Psychological Science"},{"key":"2021073021062488200_R30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(91)90196-U","article-title":"Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia","volume":"41","author":"Grace","year":"1991","journal-title":"Neuroscience"},{"key":"2021073021062488200_R31","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.neuroimage.2010.01.089","article-title":"Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control","volume":"51","author":"Hedden","year":"2015","journal-title":"Neuroimage"},{"key":"2021073021062488200_R32","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3389\/fnins.2012.00009","article-title":"Dopaminergic control of the exploration-exploitation trade-off via the basal ganglia","volume":"6","author":"Humphries","year":"2012","journal-title":"Frontiers in Neuroscience"},{"key":"2021073021062488200_R33","doi-asserted-by":"crossref","first-page":"8165","DOI":"10.1038\/ncomms9165","article-title":"An insula-frontostriatal network mediates flexible cognitive control by adaptively predicting changing control demands","volume":"6","author":"Jiang","year":"2015","journal-title":"Nature Communications"},{"key":"2021073021062488200_R34","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.neuroimage.2014.03.032","article-title":"Quantifying inter-individual anatomical variability in the subcortex using 7 T structural MRI","volume":"94","author":"Keuken","year":"2014","journal-title":"Neuroimage"},{"key":"2021073021062488200_R35","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1002\/hbm.21325","article-title":"Temporally remote destabilization of prediction after rare breaches of expectancy","volume":"33","author":"K\u00fchn","year":"2012","journal-title":"Human Brain Mapping"},{"key":"2021073021062488200_R36","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.tics.2004.12.004","article-title":"Distracted and confused?: Selective attention under load","volume":"9","author":"Lavie","year":"2005","journal-title":"Trends in Cognitive Sciences"},{"key":"2021073021062488200_R37","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0895-6111(01)00008-8","article-title":"LIPSIA\u2014A new software system for the evaluation of functional magnetic resonance images of the human brain","volume":"25","author":"Lohmann","year":"2001","journal-title":"Computerized Medical Imaging and Graphics"},{"key":"2021073021062488200_R38","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev.neuro.24.1.167","article-title":"An integrative theory of prefrontal cortex function","volume":"24","author":"Miller","year":"2001","journal-title":"Annual Review of Neuroscience"},{"key":"2021073021062488200_R39","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1006\/cogp.1999.0734","article-title":"The unity and diversity of executive functions and their contributions to complex \u201cfrontal lobe\u201d tasks: A latent variable analysis","volume":"41","author":"Miyake","year":"2000","journal-title":"Cognitive Psychology"},{"key":"2021073021062488200_R40","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1111\/j.1460-9568.2007.05949.x","article-title":"Dopamine and cognitive control: The prospect of monetary gains influences the balance between flexibility and stability in a set-shifting paradigm","volume":"26","author":"M\u00fcller","year":"2007","journal-title":"European Journal of Neuroscience"},{"key":"2021073021062488200_R41","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1126\/science.1094285","article-title":"Dissociable roles of ventral and dorsal striatum in instrumental conditioning","volume":"304","author":"O'Doherty","year":"2004","journal-title":"Science"},{"key":"2021073021062488200_R42","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1162\/089976606775093909","article-title":"Making working memory work: A computational model of learning in the prefrontal cortex and basal ganglia","volume":"18","author":"O'Reilly","year":"2006","journal-title":"Neural Computation"},{"key":"2021073021062488200_R43","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1","article-title":"Factor structure of the Barratt Impulsiveness Scale","volume":"51","author":"Patton","year":"1995","journal-title":"Journal of Clinical Psychology"},{"key":"2021073021062488200_R44","doi-asserted-by":"crossref","first-page":"R764","DOI":"10.1016\/j.cub.2013.05.041","article-title":"Interplay of hippocampus and prefrontal cortex in memory","volume":"23","author":"Preston","year":"2013","journal-title":"Current Biology"},{"key":"2021073021062488200_R45","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/nrn2022","article-title":"The short-latency dopamine signal: A role in discovering novel actions?","volume":"7","author":"Redgrave","year":"2006","journal-title":"Nature Reviews Neuroscience"},{"key":"2021073021062488200_R46","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.neuroimage.2011.11.050","article-title":"Modelling neural correlates of working memory: A coordinate-based meta-analysis","volume":"60","author":"Rottschy","year":"2012","journal-title":"Neuroimage"},{"key":"2021073021062488200_R47","doi-asserted-by":"crossref","first-page":"e36445","DOI":"10.1371\/journal.pone.0036445","article-title":"Surprised at all the entropy: Hippocampal, caudate and midbrain contributions to learning from prediction errors","volume":"7","author":"Schiffer","year":"2012","journal-title":"PLoS One"},{"key":"2021073021062488200_R48","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jphysparis.2015.02.001","article-title":"The role of prediction and outcomes in adaptive cognitive control","volume":"109","author":"Schiffer","year":"2015","journal-title":"Journal of Physiology Paris"},{"key":"2021073021062488200_R49","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.nlm.2015.11.005","article-title":"Hippocampal-medial prefrontal circuit supports memory updating during learning and post-encoding rest","volume":"134","author":"Schlichting","year":"2015","journal-title":"Neurobiology of Learning and Memory"},{"key":"2021073021062488200_R50","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1046\/j.1471-4159.2003.02050.x","article-title":"Presynaptic regulation of dopaminergic neurotransmission","volume":"87","author":"Schmitz","year":"2003","journal-title":"Journal of Neurochemistry"},{"key":"2021073021062488200_R51","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.neuropsychologia.2015.09.017","article-title":"Motor loop dysfunction causes impaired cognitive sequencing in patients suffering from Parkinson's disease","volume":"77","author":"Sch\u00f6nberger","year":"2015","journal-title":"Neuropsychologia"},{"key":"2021073021062488200_R52","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tics.2007.02.006","article-title":"Prediction of external events with our motor system: Towards a new framework","volume":"11","author":"Schubotz","year":"2007","journal-title":"Trends in Cognitive Sciences"},{"key":"2021073021062488200_R53","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.neuroimage.2003.09.014","article-title":"Functional-anatomical concepts of human premotor cortex: Evidence from fMRI and PET studies","volume":"20","author":"Schubotz","year":"2003","journal-title":"Neuroimage"},{"key":"2021073021062488200_R54","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1146\/annurev.neuro.23.1.473","article-title":"Neuronal coding of prediction errors","volume":"23","author":"Schultz","year":"2000","journal-title":"Annual Review of Neuroscience"},{"key":"2021073021062488200_R55","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/nature02581","article-title":"Temporal difference models describe higher-order learning in humans","volume":"429","author":"Seymour","year":"2004","journal-title":"Nature"},{"key":"2021073021062488200_R56","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/j.1538-7305.1948.tb01338.x","article-title":"A mathematical theory of communication","volume":"27","author":"Shannon","year":"1948","journal-title":"The Bell System Technical Journal"},{"key":"2021073021062488200_R57","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/hbm.10046","article-title":"Modulation of activity in temporal cortex during generation of inner speech","volume":"16","author":"Shergill","year":"2002","journal-title":"Human Brain Mapping"},{"key":"2021073021062488200_R58","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuroimage.2008.03.061","article-title":"Threshold-free cluster enhancement: Addressing problems of smoothing, threshold dependence and localisation in cluster inference","volume":"44","author":"Smith","year":"2009","journal-title":"Neuroimage"},{"key":"2021073021062488200_R59","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1037\/0096-3445.117.1.34","article-title":"Pragmatics of measuring recognition memory: Applications to dementia and amnesia","volume":"117","author":"Snodgrass","year":"1988","journal-title":"Journal of Experimental Psychology: General"},{"key":"2021073021062488200_R60","doi-asserted-by":"crossref","first-page":"72","DOI":"10.2307\/1412159","article-title":"The proof and measurement of association between two things","volume":"15","author":"Spearman","year":"1904","journal-title":"American Journal of Psychology"},{"key":"2021073021062488200_R61","doi-asserted-by":"crossref","first-page":"2799","DOI":"10.1016\/j.cortex.2013.04.002","article-title":"Dissociable fronto-striatal effects of dopamine D2 receptor stimulation on cognitive versus motor flexibility","volume":"49","author":"Stelzel","year":"2013","journal-title":"Cortex"},{"key":"2021073021062488200_R62","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"key":"2021073021062488200_R63","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tins.2012.02.001","article-title":"How schema and novelty augment memory formation","volume":"35","author":"van Kesteren","year":"2012","journal-title":"Trends in Neurosciences"},{"key":"2021073021062488200_R64","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1037\/a0019791","article-title":"Task switching: Interplay of reconfiguration and interference control","volume":"136","author":"Vandierendonck","year":"2010","journal-title":"Psychological Bulletin"},{"key":"2021073021062488200_R65","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1006\/nimg.1995.1023","article-title":"Analysis of fMRI time-series revisited\u2014Again","volume":"2","author":"Worsley","year":"1995","journal-title":"Neuroimage"},{"key":"2021073021062488200_R66","doi-asserted-by":"crossref","first-page":"14040","DOI":"10.1523\/JNEUROSCI.1176-13.2013","article-title":"Working memory and anticipatory set modulate midbrain and putamen activity","volume":"33","author":"Yu","year":"2013","journal-title":"Journal of Neuroscience"}],"container-title":["Journal of Cognitive Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/direct.mit.edu\/jocn\/article-pdf\/29\/2\/298\/1952311\/jocn_a_01040.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/direct.mit.edu\/jocn\/article-pdf\/29\/2\/298\/1952311\/jocn_a_01040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T02:34:51Z","timestamp":1627698891000},"score":1,"resource":{"primary":{"URL":"https:\/\/direct.mit.edu\/jocn\/article\/29\/2\/298\/28612\/Frontostriatal-Contribution-to-the-Interplay-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,1]]},"references-count":66,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,1]]},"published-print":{"date-parts":[[2017,2,1]]}},"URL":"https:\/\/doi.org\/10.1162\/jocn_a_01040","relation":{},"ISSN":["0898-929X","1530-8898"],"issn-type":[{"value":"0898-929X","type":"print"},{"value":"1530-8898","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,2]]},"published":{"date-parts":[[2017,2,1]]}}}