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We used offline continuous theta burst stimulation to assess the effect of transient inhibition of the right pre-SMA on the decision processes in a free-response two-alternative forced-choice task within the drift diffusion model framework. Participants became more cautious and set higher decision thresholds following right pre-SMA inhibition compared with inhibition of the control site (vertex). Increased decision thresholds were accompanied by an accuracy bias with no effects on post-error choice behavior. Participants also exhibited higher drift rates as a result of pre-SMA inhibition compared with the vertex inhibition. These results, in line with the striatal theory of speed\u2013accuracy tradeoff, provide evidence for the functional role of pre-SMA activity in decision threshold modulation. Our results also suggest that pre-SMA might be a part of the brain network associated with the sensory evidence integration.<\/jats:p>","DOI":"10.1162\/jocn_a_01134","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T14:01:45Z","timestamp":1491573705000},"page":"1433-1444","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":26,"title":["Inhibition of Pre\u2013Supplementary Motor Area by Continuous Theta Burst Stimulation Leads to More Cautious Decision-making and More Efficient Sensory Evidence Integration"],"prefix":"10.1162","volume":"29","author":[{"given":"Tu\u011f\u00e7e","family":"Tosun","sequence":"first","affiliation":[{"name":"Ko\u00e7 University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilara","family":"Berkay","sequence":"additional","affiliation":[{"name":"University of 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