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Specifically, we focus on how to build an interdisciplinary paradigm to investigate the effects of taking on a role on an actor's sense of self and present methods to quantify interpersonal coordination at different levels (brain, physiology, behavior) as pairs of actors rehearse an extract of a play prepared for live performance. Participants were six actors from Flute Theatre, rehearsing an extract from Shakespeare's A Midsummer Night's Dream. Sense of self was measured in terms of the response of the pFC to hearing one's own name (compared with another person's name). Interpersonal coordination was measured using wavelet coherence analysis of brain signals, heartbeats, breathing, and behavior. Findings show that it is possible to capture an actor's pFC response to their own name and that this response is suppressed when an actor rehearses a segment of the play. In addition, we found that it is possible to measure interpersonal synchrony across three modalities simultaneously. These methods open the way to new studies that can use wearable neuroimaging and hyperscanning to understand the neuroscience of social interaction and the complex social\u2013emotional processes involved in theatrical training and performing theater.<\/jats:p>","DOI":"10.1162\/jocn_a_01912","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T20:22:42Z","timestamp":1663618962000},"page":"2215-2236","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":20,"title":["Exploring Theater Neuroscience: Using Wearable Functional Near-infrared Spectroscopy to Measure the Sense of Self and Interpersonal Coordination in Professional Actors"],"prefix":"10.1162","volume":"34","author":[{"given":"Dwaynica A.","family":"Greaves","sequence":"first","affiliation":[{"name":"Goldsmiths University of London, United Kingdom"},{"name":"University College London, United 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