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This progress has allowed researchers to advance from the scientific goals of description and explanation to prediction and control. Resulting knowledge promises to improve human health and well-being. As an alternative to the extremes of reductive versus emergent approaches, however, we propose a middle way of \u201cexpansion.\u201d This expansionist approach promises to leverage the specific spatial localization, temporal precision, and directed connectivity of central neural components to ultimately link levels of analysis.<\/jats:p>","DOI":"10.1162\/jocn_a_01952","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T19:59:43Z","timestamp":1670356783000},"page":"383-387","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":2,"title":["Disentangling the Skeins of Brain"],"prefix":"10.1162","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7669-426X","authenticated-orcid":true,"given":"Brian","family":"Knutson","sequence":"first","affiliation":[{"name":"Stanford 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