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The model is shown to combine the computational economy of integrate-and-fire modeling and the physiological interpretability of conductance-based modeling. It is therefore a good candidate for affordable computational studies of neuromodulation in large networks.<\/jats:p>","DOI":"10.1162\/neco_a_01065","type":"journal-article","created":{"date-parts":[[2018,1,30]],"date-time":"2018-01-30T21:36:27Z","timestamp":1517348187000},"page":"987-1011","source":"Crossref","is-referenced-by-count":10,"title":["Robust Modulation of Integrate-and-Fire Models"],"prefix":"10.1162","volume":"30","author":[{"given":"Tomas","family":"Van Pottelbergh","sequence":"first","affiliation":[{"name":"Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Drion","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Computer Science, University of Li\u00e8ge, Li\u00e8ge 4000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolphe","family":"Sepulchre","sequence":"additional","affiliation":[{"name":"Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"281","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1993.sp019794"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00686.2005"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.167007"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0610368104"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00471.2015"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0031-14.2015"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041806"},{"key":"B8","first-page":"1923","author":"Drion G.","year":"2015","journal-title":"Proceedings of the 54th IEEE Conference on Decision and Control"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1516400112"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4195-08.2009"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(61)86902-6"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1137\/120875016"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1137\/13092263X"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00804.2017"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003040"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1126\/science.1149639"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.01.026.2009"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.14.030191.000351"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1936.0012"},{"key":"B20","volume-title":"Ionic channels of excitable membranes","author":"Hille B.","year":"2001","edition":"3"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1952.sp004764"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1109\/TNN.2003.820440"},{"key":"B23","author":"Izhikevich E. 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